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Tenectase 20mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Mar 2026 | 11:05 AM (IST)
Tenectase 20mg Injection belongs to a group of medicines called thrombolytic agents. It is used in the emergency treatment of ischemic stroke, which occurs when a blood vessel to your brain becomes blocked by a blood clot. This medicine helps to dissolve the clot and restore blood flow to your brain.
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General Information

Contains

Tenecteplase (20mg)

Marketer

Gennova Biopharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Tenectase 20mg Injection image
Tenectase 20mg Injection image

Product introduction

Tenectase 20mg Injection is given as an injection directly into a vein under the supervision of a doctor. It prevents any further damage to the brain and may even help to save your life. Your heart rate, blood pressure, and other vital signs will be monitored closely after the administration of this medicine. Your doctor may also start some other medicines to prevent the formation of new blood clots after treatment with this medication.

The most common side effect of this medicine is bleeding. It may cause injection site bleeding, nosebleeds, blood in the stool, blood in the urine, or gastrointestinal bleeding. While on treatment with this medicine, you should be careful while shaving, cutting nails, or using sharp objects.

This medicine is not suitable for everyone. Let your doctor know beforehand if you have any active bleeding from any site, recent head injury or bleeding in the brain, bleeding disorder or tendency to bleed easily, uncontrolled high blood pressure, or had any recent major surgery. Be sure to tell your doctor if you have been taking any blood thinners recently.

Uses of Tenectase Injection

Benefits of Tenectase Injection

Prevention of Ischemic stroke
Tenectase 20mg Injection is sometimes called a “clot-buster” because it dissolves harmful blood clots that cause strokes (if they are in the brain). This helps the blood flow freely around your body thereby reducing the damage caused by and the future risk of stroke. It should be given as soon as possible after the onset of stroke.

Side effects of Tenectase Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tenectase
  • Injection site bleeding
  • Nosebleeds
  • Blood in stool
  • Blood in urine
  • Gastrointestinal bleeding

How to use Tenectase Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tenectase Injection works

Tenectase 20mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Quick tips

  • Tenectase 20mg Injection is used to treat acute ischaemic stroke within 3 hours of onset of symptoms.
  • It is given as an injection into the vein under the supervision of a doctor.
  • It may increase your risk of bleeding. Inform your doctor immediately if you notice bleeding at the injection site, nose bleed, and blood in urine.
  • Continue with your diet and exercise along with previously prescribed medications for heart attack.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tenectase 20mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Tenectase 20mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Tenectase 20mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

NOT RELEVANT
Not relevant, as Tenectase 20mg Injection is intended for use in hospitalized patients.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Tenectase 20mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Tenectase 20mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Tenectase with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apixaban (Oral Route)

Do not consume Apixaban with Tenecteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Tenecteplase may increase the effect of Apixaban.
Moderate

Tranexamic Acid (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Tranexamic Acid may block the action of Tenecteplase.
Moderate

Tirofiban (Injection Route)

Do not consume Tirofiban with Tenecteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Dabigatran Etexilate (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Dasatinib (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may change the treatment accordingly.

Frequently asked questions

Tenectase 20mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Tenectase 20mg Injection.
Tenectase 20mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Yes, Tenectase 20mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Tenectase 20mg Injection can interact with several medicines. If you are already taking Tenectase 20mg Injection, do not take any other medicine without talking to your doctor.
Tenectase 20mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Tenectase 20mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Plasminogen Activators- Thrombolytics

References

  1. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 382-84.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1326.
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User feedback

Others
50%
Heart attack
50%
Excellent
54%
Average
33%
Poor
12%
No Side Effect
100%
With food
100%
Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gennova Biopharmaceuticals Ltd
Address: EMCURE HOUSE T-184MIDC BHOSARI PUNE MH 411026 IN

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Tenectase 20mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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