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Talaz LA 300mg Injection 1
Talaz LA 300mg Injection 2
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Talaz LA 300mg Injection

Olanzapine (300mg)
Genuine
Authenticity Assured
Prescription
required
Talaz LA 300mg Injection is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Sep 2026 | 01:01 AM (IST)
₹46.5 MRP ₹51.5610% off 
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Tolaz LA 300mg/vial Convenience Kit
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Talaz LA 300mg Injection
Talaz LA 300mg Injection
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Tolaz LA 300mg/vial Convenience Kit
Tolaz LA 300mg/vial Convenience Kit
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General Information

The content is shown in English
Talaz LA 300mg Injection 1
Talaz LA 300mg Injection 2

Product introduction

Talaz LA 300mg Injection is generally administered by a doctor or a nurse, typically in a hospital or clinical setting. Make sure to follow all your doctor’s instructions. Get the injection in the dose and duration as advised by your doctor. This medication must not be stopped suddenly without talking to your doctor, as it may worsen your symptoms.


Some common side effects of this medicine include dryness in the mouth, increased appetite, sleepiness, hard or infrequent stools, and restlessness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


However, this medicine may increase your weight, blood sugar, and cholesterol levels, but modifying your lifestyle by having a healthy diet and exercising regularly can reduce these side effects. You should be cautious, as in rare cases it may cause serious side effects like very high blood sugar levels or seizures.

Uses of Talaz LA Injection

Benefits of Talaz LA Injection

Treatment of Mania
Mania means extremely excited or elevated mood. Talaz LA 300mg Injection helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Talaz LA 300mg Injection will ensure that you have a better social life and are able to do daily activities more comfortably.
Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Talaz LA 300mg Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Talaz LA Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Talaz LA
  • Constipation
  • Weight gain
  • Dizziness
  • Headache
  • Akathisia (inability to stay still)
  • Postural hypotension (low blood pressure)
  • Personality changes
  • Sedation

How to use Talaz LA Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Talaz LA Injection works

Talaz LA 300mg Injection is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts, and behavior. It blocks dopamine (D₂) and serotonin (5-HT₂A) receptors in the brain, helping to balance these chemicals and reduce symptoms of schizophrenia and mania. Additionally, it interacts with other receptors, such as histamine and adrenergic receptors, which may contribute to its sedative effects.

All substitutes for Talaz LA 300mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Talaz LA 300mg Injection is less likely to cause heart and movement problems as compared to other similar medicines.
  • Use caution while driving or doing anything that requires concentration, as Talaz LA 300mg Injection can cause dizziness and sleepiness.
  • Talaz LA 300mg Injection may increase your weight, blood sugar, and cholesterol. Eat healthy, exercise regularly, and monitor your blood levels regularly.
  • To lower the chance of feeling dizzy, rise slowly if you have been sitting or lying down.
  • Do not stop taking Talaz LA 300mg Injection without talking to your doctor first, as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Talaz LA 300mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Talaz LA 300mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Talaz LA 300mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Talaz LA 300mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Talaz LA 300mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Talaz LA 300mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Talaz LA with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Olanzapine.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Haloperidol (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Haloperidol (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Pimozide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

The treatment of anxiety with Talaz LA 300mg Injection is not an approved indication. Talaz LA 300mg Injection has been studied for the treatment of anxiety disorders, but the results have not been very convincing. However, it can be used along with anxiolytics in anxiety disorders for better results.
No, Talaz LA 300mg Injection is not a sleeping pill. It belongs to the atypical antipsychotic class of medicines. It is used to treat schizophrenia and mania.
Talaz LA 300mg Injection should be avoided during pregnancy and should only be given if the benefits outweigh the risks. Using Talaz LA 300mg Injection during the last 3 months of pregnancy may cause unwanted symptoms in the unborn baby. These symptoms include shaking, muscle stiffness and/or weakness, sleepiness, agitation, breathing problems, and difficulty feeding.
You should not stop taking Talaz LA 300mg Injection without consulting your doctor. This is because sudden discontinuation of the medicine may cause unpleasant side effects, which include sweating, unable to sleep, tremors, anxiety or nausea, and vomiting. To avoid such effects, your doctor will reduce the dose gradually before stopping the treatment.
Yes, smoking interferes with the working of Talaz LA 300mg Injection, causing an increase in its metabolism. One should avoid alcohol while taking Talaz LA 300mg Injection since it may cause more drowsiness. However, if you are a smoker, then your doctor may increase your dose depending on your response to treatment.
The treatment of anxiety with Talaz LA 300mg Injection is not an approved indication. Talaz LA 300mg Injection has been studied for treatment of anxiety disorders but the results have not been very convincing. However, it can be used along with anxiolytics in anxiety disorders for better results.
No, Talaz LA 300mg Injection is not a sleeping pill. It belongs to the atypical antipsychotic class of medicines. It is used to treat schizophrenia. Schizophrenia is a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions. Talaz LA 300mg Injection also helps with bipolar disorder (manic depressive disorder). It is a disease that causes episodes of depression, mania, and other abnormal moods.
Talaz LA 300mg Injection may start showing initial improvement within 1-2 week of starting. However, for full benefits it may take about 4-6 weeks. You should continue taking it and consult your doctor in case you feel that Talaz LA 300mg Injection is not helping you.
Talaz LA 300mg Injection can cause serious side effects which include increased risk of death in elderly people who are confused, have memory loss and have lost touch with reality (dementia-related psychosis). It is important to know that it may increase blood sugar levels in diabetics and also in patients who never had diabetes. Furthermore, it may cause weight gain and high fat levels in the blood which is more common in teenagers.
Talaz LA 300mg Injection should be avoided during pregnancy and should only be given if benefits outweigh the risk. Using Talaz LA 300mg Injection during last 3 months of pregnancy may cause unwanted symptoms in the unborn baby. These symptoms include shaking, muscle stiffness and/or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding.
You should not stop taking Talaz LA 300mg Injection without consulting your doctor. This is because sudden discontinuation of the medicine may cause unpleasant side effects which include sweating, unable to sleep, tremor, anxiety or nausea, and vomiting. To avoid such effects, your doctor will reduce the dose gradually before stopping the treatment.
Yes, smoking interferes with working of Talaz LA 300mg Injection causing an increase in its metabolism. One should avoid alcohol while taking Talaz LA 300mg Injection since it may cause more drowsiness. However, if you are a smoker then your doctor may increase your dose depending on your response to treatment.

Fact Box

Chemical Class

Benzodiazepines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

  1. Stahl SM, editor. Olanzapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 485-92.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1013-16.
  3. Olanzapine. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2013 [revised 22 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  5. Olanzapine [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2002. [Accessed 28 Mar. 2023] (online) Available from:
  6. Olanzapine [FDA Label]. Indianapolis, IN: Lilly USA, LLC; 2025. [Accessed 10 Mar. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
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