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Tafmate 25mg Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 13 Oct 2025 | 04:22 PM (IST)
Tafmate 25mg Tablet is used in the treatment of chronic hepatitis B virus (HBV) infection. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.
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Tafmate 25mg Tablet
Tafmate 25mg Tablet
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General Information

The content is shown in English
Tafmate 25mg Tablet image
Tafmate 25mg Tablet image

Product introduction

Tafmate 25mg Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses, and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. It is important to keep taking them until your doctor tells you it is safe to stop.


Common side effects of this medicine include headache, diarrhea, nausea, joint pain, abdominal pain, and indigestion. Please consult your doctor if it persists for a longer duration. These are usually not serious, but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.


Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol, as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes if you are HIV positive. Talk to your doctor about safe ways, like condoms, to prevent HIV transmission during sex.

Benefits of Tafmate Tablet

Treatment of Hepatitis B virus (HBV) infection
Chronic hepatitis B virus infection is a serious liver infection that has been there for at least 6 months and is still not cured. Tafmate 25mg Tablet helps treat this infection effectively. It lowers the chances of complications, such as new infections, and improves one’s quality of life. If this infection is not treated, it can lead to severe liver damage, which can cause other life-threatening problems, such as liver failure, or may also be fatal.

Side effects of Tafmate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tafmate
  • Headache
  • Diarrhea
  • Nausea
  • Fatigue
  • Abdominal pain
  • Cough
  • Back pain
  • Indigestion
  • Joint pain

How to use Tafmate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tafmate 25mg Tablet is to be taken with food.

How Tafmate Tablet works

Tafmate 25mg Tablet is an antiviral medication. It prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Quick tips

  • Take it with food, as this increases the absorption of the medicine into the body.
  • Tafmate 25mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus, and blood cells in your blood.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tafmate 25mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Tafmate 25mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Tafmate 25mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

UNSAFE
Tafmate 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Tafmate 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tafmate 25mg Tablet may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Tafmate 25mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tafmate 25mg Tablet may not be needed in these patients. Please consult your doctor.

Interaction with drugs

Taking Tafmate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Fosphenytoin (Injection Route)

Do not use Tenofovir Alafenamide with Fosphenytoin. If concurrent use is essential, talk to your doctor. Fosphenytoin may reduce blood levels of Tenofovir Alafenamide.
Severe

Oxcarbazepine (Oral Route)

Do not use Tenofovir Alafenamide with Oxcarbazepine. If concurrent use is essential, talk to your doctor. Oxcarbazepine may reduce blood levels of Tenofovir Alafenamide.
Severe

Phenobarbitone (Injection Route)

Do not use Tenofovir Alafenamide with Phenobarbitone. If concurrent use is essential, talk to your doctor. Phenobarbitone may reduce blood levels of Tenofovir Alafenamide.
Severe

Phenobarbitone (Oral Route)

Do not use Tenofovir Alafenamide with Phenobarbitone. If concurrent use is essential, talk to your doctor. Phenobarbitone may reduce blood levels of Tenofovir Alafenamide.
Severe

Phenytoin (Injection Route)

Do not use Tenofovir Alafenamide with Phenytoin. If concurrent use is essential, talk to your doctor. Phenytoin may reduce blood levels of Tenofovir Alafenamide.

Frequently asked questions

In case of HIV-1 infection, Tafmate 25mg Tablet may reduce the risk of passing the virus to others, but the chances of infecting others persist. However, in the case of HBV infection, Tafmate 25mg Tablet has not proven to reduce the risk of transmitting the virus to others. Therefore, patients with both HIV-1 infection and HBV infection should practice safe sex and should not share dirty needles.
Tafmate 25mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
You should take Tafmate 25mg Tablet in the dose and duration advised by your doctor. Tafmate 25mg Tablet works best when taken with meals or just afterwards. However, taking it without food does not reduce its effectiveness. If you have any doubts, consult your doctor.
Duration of treatment will depend on the severity of HBV infection. You will need to take periodic blood tests to keep a check on the viral load and number of T cells. Your doctor will then decide the duration of the medicine accordingly. In some cases, treatment is required lifelong.
If vomiting occurs within 1 hour of taking Tafmate 25mg Tablet, then you should take another dose. However, if you vomit more than an hour after taking Tafmate 25mg Tablet, then you need not take another dose. Consult your doctor if you have vomiting every time you take Tafmate 25mg Tablet or if the vomiting persists for a longer duration.
If you forget to take Tafmate 25mg Tablet within 12 hours of the time you usually take it, take Tafmate 25mg Tablet with food as soon as possible and resume the normal dosing schedule. However, if it has been more than 12 hours since you took the medicine and it is almost time for the next dose, skip the missed dose and simply resume the usual dosing schedule.

Fact Box

Chemical Class

Nucleotide analog

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: RSL Bioscience Pvt Ltd
Address: B-57, First Floor, Amar Colony, Nangloi, New Delhi-110041.India

Vendor Details

Country of origin: India
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