Synstim 50mg Injection
Prescription RequiredProduct introduction
Synstim 50mg Injection is an anti-cancer drug used in the treatment of ovarian cancer and a type of cancer of bone marrow called multiple myeloma. It may also be used to treat other conditions, as determined by the doctor.
Synstim 50mg Injection is administered by a doctor or a nurse into the vein. Do not self administer this medicine at home. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes skin more sensitive towards sunlight, wear protective clothing or use sunscreen.
The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells) and hair loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Inform your doctor if you observe signs of infections such as fever, chills, body ache or if you have unusual bruising or bleeding and bleeding gums or blood in your urine or stool.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Synstim Injection
Benefits of Synstim Injection
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Synstim 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Synstim Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Synstim
- Hair loss
- Low blood platelets
- Diarrhea
- Decreased white blood cell count
- Nausea
- Vomiting
- Stomatitis (Inflammation of the mouth)
- Anemia (low number of red blood cells)
How to use Synstim Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Synstim Injection works
Synstim 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Synstim 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Synstim 50mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Synstim 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Synstim 50mg Injection may cause side effects that could affect your ability to drive.
Kidney
CAUTION
Synstim 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Synstim 50mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
What if you forget to take Synstim Injection?
If you missed a dose of Synstim 50mg Injection, consult your doctor. It is important not to miss your dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Synstim 50mg Injection should be taken as per dose and duration suggested by the doctor.
Fact Box
Chemical Class
Phenylalanine derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating Agents
Interaction with drugs
Taking Synstim with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not use Melphalan with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) is essential, ensure a gap of At
Do not use Melphalan with Purified Vi Polysaccharide Typhoid Vaccine. If Purified Vi Polysaccharide Typhoid Vaccine is essential, ensure a gap of At least 6 months after discontinu
Do not consume Filgrastim from 24 hours before or 24 hours after taking Melphalan. Melphalan may reduce the efficacy of Filgrastim.
Do not use Melphalan with Cholera Vaccine (Inactivated). If Cholera Vaccine (Inactivated) is essential, ensure a gap of At least 6 months after discontinuing Melphalan. Please cons
Do not consume Pegfilgrastim from 24 hours before or 24 hours after taking Melphalan. Melphalan may reduce the efficacy of Pegfilgrastim.
Patient concerns
FAQs
What is Synstim 50mg Injection usually given for?
Synstim 50mg Injection is used to treat certain cancers, mainly multiple myeloma and ovarian cancer. Doctors may use it alone or with other cancer medicines, depending on the treatment plan.<br>
Who should not receive Synstim 50mg Injection?
Individuals should not receive Synstim 50mg Injection if they are allergic to melphalan or its ingredients, are not able to safely receive medicines that suppress the bone marrow, or are experiencing severe infections or already have dangerously low blood counts. Your doctor will check these before starting treatment.<br>
Why do doctors monitor blood counts so closely with Synstim 50mg Injection?
Synstim 50mg Injection can significantly lower white cells, red cells, and platelets, which may increase the risk of infection, anemia, and bleeding. This medicine can sometimes be delayed, so monitoring continues for weeks after each dose.<br>
Can Synstim 50mg Injection affect my risk of infections?
Yes. Because Synstim 50mg Injection weakens the immune system, you may be more likely to get infections or have infections become serious quickly. Fever, chills, sore throat, or flu-like symptoms should be reported immediately.<br>
What serious side effects of Synstim 50mg Injection need immediate medical attention?
Serious side effects of Synstim 50mg Injection can include unusual bleeding or bruising, trouble breathing, fever, or signs of infection, severe tiredness, allergic reactions such as rash, swelling, or difficulty breathing. These symptoms can signal bone marrow suppression or severe hypersensitivity, and you should seek immediate medical attention if you experience any of them.<br>
Can Synstim 50mg Injection cause long-term complications?
Synstim 50mg Injection may increase the risk of secondary cancers, especially leukemia, months, or years later. This is a known but uncommon risk with many chemotherapy medicines. Doctors use the lowest effective dose to reduce this risk.<br>
Is Synstim 50mg Injection safe for people with kidney problems?
Kidney function affects how Synstim 50mg Injection is cleared from the body. People with kidney impairment may have stronger side effects, so doctors often use lower doses and monitor kidney tests closely.<br>
Why do I need to stay well-hydrated during Synstim 50mg Injection treatment?
During Synstim 50mg Injection treatment, hydration supports kidney function and helps your body handle the breakdown products from cancer cell destruction, reducing the risk of complications like kidney strain. Your doctor and care team may give IV fluids if needed.<br>
Can Synstim 50mg Injection affect my fertility?
Yes. Synstim 50mg Injection may reduce fertility in both men and women. Patients may be offered sperm or egg preservation options before starting treatment. This conversation usually happens early in the cancer-care process.<br>
What precautions should I follow after getting Synstim 50mg Injection?
After getting Synstim 50mg Injection, your care team may advise avoiding sick contacts, watching for fever or bleeding, reporting skin changes or rashes, and keeping all blood-test appointments. These help detect complications early and keep treatment safe.<br>
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 860-61.
- Mephalan. Dublin, Ireland: Aspen; 2004 [revised Aug. 2014]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Zydus Lifesciences Ltd
Address: Zydus Corporate Park, 4Th Floor, B Wing, Plot No 103, Near Nirma University,S G Highway, Ahmedabad, 382481 / Scheme No. 63, Survey No. 536, Khoraj(Gandhinagar), Near Vaishnodevi Circle, Ahmedabad - 382481, Gujarat.
Country of origin: India
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₹2754
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MRP₹2807 2% OFF
1.0 Injection in 1 vial
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