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Synep 10mg Injection

Phenylephrine (10mg)
Genuine
Authenticity Assured
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Synep 10mg Injection is used to treat hypotension (low blood pressure) which occurs during anesthesia or due to any medicine. It helps to maintain normal level of blood pressure.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 24 Sep 2025 | 12:58 PM (IST)
₹180 MRP ₹196.889% off 
 
 
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General Information

The content is shown in English
Synep 10mg Injection image
Synep 10mg Injection image

Product introduction

Synep 10mg Injection is given under the supervision of healthcare professionals. You should not self-administer this medicine at home. The dose and duration depends on the seriousness of your condition. You should have your injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Common side effects of this medicine include nausea and vomiting, and headache. Consult with your doctor if any of these side effects persist and do not go away with time. Before taking this medicine, you should let your doctor know of all the other medicines you are taking, have any heart, liver, or kidney disease. Pregnant or breastfeeding mothers should consult their doctor before using this medicine.

Uses of Synep Injection

Benefits of Synep Injection

Low blood pressure
Synep 10mg Injection is used in adults and children to relieve low blood pressure which may occur during an operation or after an injury. It is injected by a doctor or a nurse into a vein (intravenously), a muscle (intramuscularly), or directly under the skin (subcutaneously). Its effectiveness depends on the way it is administered and the effect may last from 20 minutes to 2 hours. This medicine helps to bring back the blood pressure within normal range and therefore prevents any serious complications that might have otherwise followed.

How to use Synep Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Synep Injection works

Synep 10mg Injection is an blood-pressure increasing medication. It works on the receptors on blood vessels and causes them to contract and narrow. This raises the low blood pressure.

All substitutes for Synep 10mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Synep 10mg Injection is given to raise low blood pressure which may occur during surgery.
  • Synep 10mg Injection is always given by a doctor or nurse and should never be self-administered.
  • Do not use this medicine without a doctor's advice if you are pregnant or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Synep 10mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Synep 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Synep 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

SAFE
Synep 10mg Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Synep 10mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Synep 10mg Injection may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advised for dose adjustment.
Liver

Liver

CAUTION
Synep 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Synep 10mg Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Synep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Phenylephrine. If concurrent use is essential, please consult your doctor.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Phenylephrine. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Phenylephrine. Please consult your doctor.
Severe

Selegiline (Oral Route)

Do not consume Selegiline with Phenylephrine. If concurrent use is essential, your doctor may monitor your blood pressure frequently.
Moderate

Linezolid (Oral Route)

Do not consume Linezolid with Phenylephrine. If concurrent use is essential, please consult your doctor. They may monitor your blood pressure frequently.
Moderate

Linezolid (Injection Route)

Do not consume Linezolid with Phenylephrine. If concurrent use is essential, please consult your doctor. They may monitor your blood pressure frequently.

Frequently asked questions

Synep 10mg Injection is a medicine given in hospitals to quickly raise blood pressure in adults when it drops too low, usually during surgery under anesthesia.
Individuals should not receive Synep 10mg Injection if they are allergic to it or any of its ingredients. Always tell your doctor about allergies, past reactions, or sensitivities to similar medicines before use.
Yes, Synep 10mg Injection can cause the heart to slow down (bradycardia), reduce blood flow from the heart, or worsen conditions like chest pain (angina), heart failure, or pulmonary hypertension. Patients with heart problems need careful monitoring.
Serious side effects of Synep 10mg Injection include dangerously high blood pressure, irregular heartbeat, chest pain, breathing problems, kidney problems, and tissue damage at the injection site if the medicine leaks outside the vein.
Yes, if the medicine leaks outside the vein while receiving Synep 10mg Injection, it may cause severe skin or tissue damage, including tissue death (necrosis). The injection site must always be checked to ensure the medicine flows properly.
Yes, Synep 10mg Injection may reduce blood flow to organs like the intestines, kidneys, or extremities, especially in patients with blood vessel diseases. This can lead to organ damage if not monitored.
Patients with kidney disease may be more sensitive to Synep 10mg Injection and require lower doses, while those with severe liver disease may respond less and require higher doses. Careful dose adjustments are needed.

Fact Box

Chemical Class

1-Hydroxy-4-Unsubstituted Benzenoids Derivative

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Sympathomimetics- Alpha-1 (Nasal)

References

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1110.
  3. Phenylephrine. King William Street, London: Amdipharm UK Limited; 1999 [revised 20 Nov. 2018]. [Accessed 01 Apr. 2019] (online) Available from:
  4. Phenylephrine. Chesterfield, MO: Eclat Pharmaceuticals; 1954. [Accessed 01 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Molekule India Pvt Ltd
Address: CRIMPAGE CORPORATION, 3RD FLOOR, PLOT NO. 57, STREET NO. 17, MIDC, MAROL, ANDHERI (EAST), MUMBAI MH 400093 IN , - , .

Vendor Details

Country of origin: India
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