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Sunixar 25 Capsule

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Jan 2026 | 10:15 AM (IST)
Sunixar 25 Capsule is a medicine used in the treatment of kidney cancer and gastrointestinal stromal tumor. It works by blocking specific enzymes that promote the growth of cancer cells. This way it shrinks the tumor and slows down its progression.
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Sunixar 25 Capsule is currently sold out
Same composition alternative:
Sutib 25 Capsule
₹3591₹3942
Available alternative from Glenmark Pharmaceuticals
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Sunixar 25 Capsule
Sunixar 25 Capsule
strip of 7 capsules
₹721
₹749
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Same composition
Sutib 25 Capsule
Sutib 25 Capsule
bottle of 28 capsules
by Glenmark Pharmaceuticals Ltd
Get by 17 Apr
₹3591
₹128.25 per capsule

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General Information

The content is shown in English
Sunixar 25 Capsule image
Sunixar 25 Capsule image
Sunixar 25 Capsule image
Sunixar 25 Capsule image
Sunixar 25 Capsule image
Sunixar 25 Capsule image

Product introduction

Sunixar 25 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Common side effects of this medicine include weakness, diarrhea, nausea, vomiting, taste change, and decreased appetite. The doctor may advise for regular monitoring of blood pressure and thyroid gland function while taking this medicine. It may decrease blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, if you are diabetic then it is important to check your blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or bleeding disorder. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Sunixar Capsule

Kidney cancer
Kidney cancer is a type of cancer that begins in the cells of the kidneys and can grow and spread if not treated. Sunixar 25 Capsule works by blocking specific proteins that help cancer cells grow and multiply. This slows the progression of the disease and helps reduce tumor size, improving overall outcomes for patients with advanced kidney cancer
Gastrointestinal stromal tumour
Gastrointestinal stromal tumour is a rare cancer that forms in the digestive tract, usually the stomach or small intestine. Sunixar 25 Capsule is used when the tumor cannot be surgically removed or has spread, especially after resistance to other treatments like imatinib. It targets abnormal enzymes in the cancer cells, slowing or stopping their growth and helping to manage the tumor more effectively.

Side effects of Sunixar Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sunixar
  • Decreased appetite
  • Mucositis
  • High blood pressure
  • Hand-foot syndrome
  • Bleeding disorder
  • Nausea
  • Vomiting
  • Weakness
  • Fatigue
  • Diarrhea
  • Taste change

How to use Sunixar Capsule

Take this medicine in the dose and duration as advised by your doctor. Sunixar 25 Capsule may be taken with or without food.

How Sunixar Capsule works

Sunixar 25 Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.

Quick tips

  • Sunixar 25 Capsule is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • Monitoring of thyroid gland function is required while taking this medicine.  Inform your doctor if you notice symptoms of weight gain, dry skin, and hair.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Inform your doctor about the consumption of Sunixar 25 Capsule before going for surgical procedure.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sunixar 25 Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Sunixar 25 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Sunixar 25 Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Sunixar 25 Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Sunixar 25 Capsule may cause dizziness during the treatment. Do not drive or operate machineries if you experience this while on treatment with the medicine.
Kidney

Kidney

CAUTION
Sunixar 25 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Sunixar 25 Capsule in patients with liver disease.

Interaction with drugs

Taking Sunixar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Sparfloxacin (Oral Route)

Do not consume Sparfloxacin with Sunitinib.
Life-threatening

Ranolazine (Oral Route)

Do not consume Ranolazine with Sunitinib.
Life-threatening

Sildenafil (Oral Route)

Do not consume Sildenafil with Sunitinib.
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Sunitinib.
Life-threatening

Escitalopram Oxalate (Oral Route)

Do not consume Escitalopram Oxalate with Sunitinib.

Frequently asked questions

You should take Sunixar 25 Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Sunixar 25 Capsule, as the chances of side effects may be more.
During treatment with Sunixar 25 Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Sunixar 25 Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.
Sunixar 25 Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Sunixar 25 Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.
There are no generics available for Sunixar 25 Capsule. Sunixar 25 Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.
There are no studies that support the use of Sunixar 25 Capsule with other chemotherapy medicines. For example, Sunixar 25 Capsule is used in Gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel, when imatinib (another anticancer medicine) no longer works or the patient cannot take imatinib.
Yes, Sunixar 25 Capsule may decrease your blood sugar levels. Therefore, if you are a diabetic, you need to be extra careful since your blood sugar levels may become so low that you may become unconscious. Keep a regular check on the blood sugar levels, based on which your dose of anti-diabetics may be changed.
Generally, Sunixar 25 Capsule is known to cause an increase in blood pressure. Therefore, it is important that you keep a regular check on your blood pressure levels. Inform your doctor if you have severe headache, dizziness, lightheadedness or change in vision. Your doctor may prescribe a medicine to treat the increase blood pressure or may stop your treatment temporarily till your blood pressure returns to normal.
You should take Sunixar 25 Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Sunixar 25 Capsule, as the chances of side effects may be more.
During treatment with Sunixar 25 Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Sunixar 25 Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.
Sunixar 25 Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Sunixar 25 Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.
There are no studies that support the use of Sunixar 25 Capsule with other chemotherapy medicines. For example, Sunixar 25 Capsule is used in Gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel, when imatinib (another anticancer medicine) no longer works or the patient cannot take imatinib.
Yes, Sunixar 25 Capsule may decrease your blood sugar levels. Therefore, if you are a diabetic, you need to be extra careful since your blood sugar levels may become so low that you may become unconscious. Keep a regular check on the blood sugar levels, based on which your dose of anti-diabetics may be changed.
Generally, Sunixar 25 Capsule is known to cause an increase in blood pressure. Therefore, it is important that you keep a regular check on your blood pressure levels. Inform your doctor if you have severe headache, dizziness, lightheadedness or change in vision. Your doctor may prescribe a medicine to treat the increase blood pressure or may stop your treatment temporarily till your blood pressure returns to normal.
There are no generics available for Sunixar 25 Capsule. Sunixar 25 Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.

Fact Box

Chemical Class

Indolines

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1304.
  4. Sunitinib malate [Prescribing Information]. New York, New York: Pfizer Inc.; 2021. [Accessed 25 Oct. 2023] (online) Available from:
  5. Sunitinib malate. Sandwich, Kent: Pfizer Limited; 2006 [revised Feb. 2019]. [Accessed 27 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

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Country of origin: India
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