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Sodium Stibogluconate Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 10 Apr 2026 | 10:57 AM (IST)
Sodium Stibogluconate Injection is an antibiotic. It is used in the treatment of kala-azar (a parasitic disease spread by the bite of infected sand flies). It inhibits the growth of the parasite and kills it, thus relieving your infection.
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General Information

The content is shown in English
Sodium Stibogluconate Injection image
Sodium Stibogluconate Injection image

Product introduction

Sodium Stibogluconate Injection is given as an injection into a vein (intravenous) or muscle (intramuscular). Your doctor will decide which one is best for you. It is administered by a healthcare professional. Kindly do not self-administer. Avoid skipping any doses and finish the full course of treatment even if you feel better.

Some people may experience vomiting, headache, nausea, diarrhea, abdominal pain, pain in the muscle and joints, and tiredness as the side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. Please consult your doctor if these side effects persist for a longer duration. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue, or face, shortness of breath, or breathing problems.

You should not take this medicine if you are allergic to any of its ingredients. Special care should be taken in people with kidney, liver, or heart problems while taking this medicine. Inform your doctor if you have been treated for kala-azar earlier or have sores in your mouth, nose, or throat. Your doctor may advise for an electrocardiogram (ECG) to check how well your heart works, before and during your treatment.

Uses of Sodium Stibogluconate Injection

Benefits of Sodium Stibogluconate Injection

Kala-azar
Sodium Stibogluconate Injection is an antibiotic medicine and is used to treat kala-azar, a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected sand flies. It kills the infection-causing parasite and stops the further spread of the infection. This medicine is given by a doctor or nurse and should not be self-administered. Refrain from taking any other medicines along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Sodium Stibogluconate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sodium Stibogluconate
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Tiredness
  • Muscle pain
  • Joint pain

How to use Sodium Stibogluconate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sodium Stibogluconate Injection works

Sodium Stibogluconate Injection is an antibiotic. It inhibits the growth of the parasite and kills it, thus relieving your infection

Quick tips

  • Sodium Stibogluconate Injection is given as an injection into veins or muscle by a healthcare professional.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • You may be monitored with ECG to check for heart function before starting the treatment.
  • Inform your doctor if you experience shortness of breath, rash, itching and swelling of face or tongue.
     

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sodium Stibogluconate Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Sodium Stibogluconate Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Sodium Stibogluconate Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Sodium Stibogluconate Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Sodium Stibogluconate Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Sodium Stibogluconate Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Sodium Stibogluconate Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Sodium Stibogluconate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Sodium Stibogluconate.
Severe

Thioridazine (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Pimozide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Haloperidol (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Sodium Stibogluconate Injection is used to treat certain types of leishmaniasis (a disease caused by the bite of certain sandflies), such as visceral leishmaniasis (a disease affecting the internal organs), cutaneous leishmaniasis (a disease affecting the skin) or mucosal leishmaniasis (a disease affecting the nose, mouth or throat).
Use of Sodium Stibogluconate Injection should be avoided in patients who are allergic to Sodium Stibogluconate Injection or any of its components. However, if you are not aware of any allergy or if you are using Sodium Stibogluconate Injection for the first time, consult your doctor.
Before starting treatment with Sodium Stibogluconate Injection, tell your doctor if you have any other health problems, like kidney or heart problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are taking any other medicines or if you are pregnant or breastfeeding.
Sodium Stibogluconate Injection should be administered either into a vein (intravenously) or into a muscle (intramuscularly), under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Sodium Stibogluconate Injection.
Sodium Stibogluconate Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Sufficient information regarding the use of this medicine during pregnancy is not available. If leishmaniasis is not treated during pregnancy it may lead to congenital leishmaniasis in the newborn. Some studies suggest that the use of Sodium Stibogluconate Injection during pregnancy may be harmful for the development of the fetus (baby). Therefore, Sodium Stibogluconate Injection is advised only if the benefits of the medicine outweigh the risks involved with its use. If you are planning to conceive, are pregnant, or breastfeeding, inform your doctor before taking Sodium Stibogluconate Injection.

Fact Box

Chemical Class

Dicarboxylic acid derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Anti-Leishmaniasis

Related lab tests

References

  1. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1435-36.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Albert David Ltd
Address: D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (WB) / 5/11, D. Gupta Lane, Kolkata 700 050, India

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Country of origin: India
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