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Sobicare 500 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Sobicare 500 Tablet is used for the management of metabolic acidosis associated with conditions such as chronic kidney disease (CKD), acute renal failure, diabetic ketoacidosis, severe diarrhea, or shock. It helps delay CKD progression and improve overall survival.
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Sobicare 500 Tablet is currently sold out
Same composition alternative:
Dosmiford 500mg Tablet
₹22.2₹32.81
31% cheaper alternative available
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Sobicare 500 Tablet
Sobicare 500 Tablet
strip of 10 tablets
₹32.2
₹35.63
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Same composition
Dosmiford 500mg Tablet
Dosmiford 500mg Tablet
strip of 10 tablets
Sodium Bicarbonate (500mg)
by Leeford Healthcare Ltd
Get in 60 mins
₹22.2
₹1.89 per tablet

₹18.9

order for
₹1200

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General Information

Contains

Sodium Bicarbonate (500mg)

Marketer

Mactif Pharma

Storage

Store below 30°C
The content is shown in English
Sobicare 500 Tablet image
Sobicare 500 Tablet image
Sobicare 500 Tablet image
Sobicare 500 Tablet image

Product introduction

Sobicare 500 Tablet relieves irritation by producing carbon dioxide, which neutralizes the acid present in the stomach. It also increases the pH of blood and urine, thereby correcting acid indigestion, heartburn. Additionally, it helps in the removal of toxic substances from the body in certain types of poisoning.


Sobicare 500 Tablet may be taken with or without food in a dose and duration as advised by the doctor. Excessive intake may cause an electrolyte imbalance, leading to unwanted side effects. Keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back and your condition may worsen.


Common side effects of this medicine include high sodium levels, cerebral edema, alkalosis, and hypokalemia. Let your doctor know if any of these side effects persist or get worse. They may be able to help by adjusting the dosage or by prescribing you an alternate medicine.


It is important to consult a doctor before taking Sobicare 500 Tablet if you are suffering from stomach and kidney disease. Let your doctor also know about all other medications you are taking, as some may affect, or be affected by, this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Uses of Sobicare Tablet

  • Management of Metabolic acidosis

Benefits of Sobicare Tablet

Management of Metabolic acidosis
Sobicare 500 Tablet helps manage metabolic acidosis, a condition where the body produces too much acid or cannot remove it effectively, leading to a decrease in blood pH. This often occurs in people with chronic kidney disease, diabetic ketoacidosis, or severe dehydration, and can cause fatigue, shortness of breath, and muscle weakness. Sobicare 500 Tablet acts as an alkalinizing agent that neutralizes excess acid and restores the body’s normal pH balance. Correcting this imbalance improves breathing, relieves discomfort related to acid buildup.

Side effects of Sobicare Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sobicare
  • Increased sodium level in blood
  • Brain swelling
  • Alkalosis
  • Decreased potassium level in blood

How to use Sobicare Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sobicare 500 Tablet may be taken with or without food.

How Sobicare Tablet works

Sobicare 500 Tablet works primarily by providing a source of bicarbonate ions to the body. Sobicare 500 Tablet neutralizes the acidity in the stomach, providing relief from the discomfort of acid reflux or heartburn. It can help temporarily increase the pH of the blood, making it less acidic. This property can be useful in certain medical situations, such as metabolic acidosis, where the body becomes too acidic due to conditions like kidney dysfunction or severe dehydration. Sobicare 500 Tablet may also help in cases where the urine needs to be less acidic, such as when trying to promote the excretion of certain drugs or when managing certain urinary tract conditions.

All substitutes for Sobicare 500 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Dosmiford 500mg Tablet

by Leeford Healthcare Ltd
₹2.22/tablet
31% cheaper
<h3 class=bodySemiBold>Dosmiford 500mg Tablet</h3>

Nodosis Tablet

by Steadfast Medishield Pvt Ltd
₹3.13/tablet
3% cheaper
<h3 class=bodySemiBold>Nodosis Tablet</h3>

Sobisis 500mg Tablet

by La Renon Healthcare Private Limited
₹3.93/tablet
22% costlier
<h3 class=bodySemiBold>Sobisis 500mg Tablet</h3>

Nodosis GST Tablet

by Steadfast Medishield Pvt Ltd
₹3.89/tablet
21% costlier
<h3 class=bodySemiBold>Nodosis GST Tablet</h3>

Sobisis EC 500 Tablet

by La Renon Healthcare Private Limited
₹4.24/tablet
32% costlier
<h3 class=bodySemiBold>Sobisis EC 500 Tablet</h3>

Quick tips

  • Take Sobicare 500 Tablet at least 1 to 2 hours before or after other medications, as it may affect their absorption.
  • Avoid taking it with large meals regularly, as excessive use can lead to rebound acidity.
  • Avoid Sobicare 500 Tablet, if you show signs of appendicitis or inflammed bowel (such as lower abdominal pain, cramping, bloating, nausea, vomiting). Please consult your doctor.
  • Do not use it as a long-term solution for heartburn or acidity without medical supervision.
  • Monitor sodium intake if you have high blood pressure, kidney issues, or are on a salt-restricted diet.
  • Dissolve the Sobicare 500 Tablet completely in water before consuming to reduce the risk of stomach discomfort.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sobicare 500 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Sobicare 500 Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Sobicare 500 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Sobicare 500 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Sobicare 500 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Sobicare 500 Tablet in patients with liver disease.

Interaction with drugs

Taking Sobicare with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Ofloxacin (Oral Route)

To take Ofloxacin, ensure a gap of at least 6 hours before or after taking Sodium Bicarbonate. Sodium Bicarbonate may reduce the efficacy of Ofloxacin.
Moderate

Chloroquine (Oral Route)

Ensure a gap of at least 4 hours between taking Chloroquine and Sodium Bicarbonate.
Moderate

Ursodeoxycholic Acid (Oral Route)

Ensure a gap of at least 2 hours between taking Ursodeoxycholic Acid and Sodium Bicarbonate.
Moderate

Azithromycin (Oral Route)

Do not consume Azithromycin with Sodium Bicarbonate. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Sodium Bicarbonate may reduce blood levels of Azithromycin.
Moderate

Sparfloxacin (Oral Route)

To take Sparfloxacin, ensure a gap of at least 6 hours before or after taking Sodium Bicarbonate. Sodium Bicarbonate may reduce the efficacy of Sparfloxacin.

Frequently asked questions

Medical-grade baking soda (present in Sobicare 500 Tablet) includes medical-grade purity and quality control, precise dosing in medical formulations, professional oversight of treatment, and specific medical packaging. However, regular baking soda is mostly used for cooking and baking. It helps the baked product rise and be fluffy. Always use the prescribed form rather than kitchen baking soda.
You can take Sobicare 500 Tablet for heartburn when symptoms occur, while for chronic conditions, you should take it as prescribed by your doctor. It is usually taken between meals, and it is better not to take it within 2 hours of other medications. Follow specific instructions for your condition.
You should seek medical attention if you experience serious side effects of Sobicare 500 Tablet such as severe stomach pain, swelling of feet or ankles, unusual weakness, slow breathing, and mood changes. These could indicate serious complications.
Individuals should exercise extra caution if they have high blood pressure, heart problems, kidney disease, liver problems, and are on a salt-restricted diet. They should consult their doctor before use.
You should only use Sobicare 500 Tablet for long-term use under medical supervision. Regular monitoring may be needed in this case. Blood tests might be required, and dosage may need adjustment over time. Always discuss duration with your doctor.

Fact Box

Chemical Class

Organic carbonic acids

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Antacids

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1069.
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  3. Sodium Bicarbonate [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Provate Limited. [Accessed 01 Aug. 2023]. (online) Available from:
  4. Sodium Bicarbonate [Product Label]. Mehatpur, India: Stanford Laboratories Private Limited. [Accessed 06 Aug. 2023]. (online) Available from:
  5. Leeford: Sodium Bicarbonate [Product Information]. [Accessed 27 Oct. 2025]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mactif Pharma
Address: no. 113, 1st floor, tirupati complex, krishna nagar, ahmedabad-380001, gujarat, india / LG/7 Kautilya apartment Near Hetvi Tower Anandnagar Road Ahmedabad 380015

Vendor Details

Country of origin: India

Lab tests offered by us

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