Simavir 250mg Tablet is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex virus infections, shingles, and genital herpes infection. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection.

Simavir 250mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It may be taken with or without food, but it is better to take it at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule, to avoid overdose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

Some side effects of this medicine include headache, dizziness, vomiting, nausea, fatigue, and fever. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Simavir Tablet

Benefits of Simavir Tablet

In Herpes labialis

Herpes labialis, commonly known as cold sores, is a viral infection that primarily affects the lip. Symptoms typically include a burning pain followed by small blisters or sores. The first attack may also be accompanied by fever, sore throat, and enlarged lymph nodes. Simavir 250mg Tablet can speed up healing of herpes labialis and also prevent recurrence of the sores.

In Herpes Simplex Virus Infections

Simavir 250mg Tablet is an antiviral medicine. It slows the growth and spread of the herpes virus in the body. It will not cure herpes and neither it prevents passing on the infection to others. However, it can speed up healing of the sores and decrease the symptoms such as tingling, pain, burning, itching. Follow your doctor’s instructions carefully to get maximum benefit.

In Shingles

Shingles is a viral infection that causes a painful rash. Simavir 250mg Tablet can shorten the length and severity of shingles. It is most effective if you start taking it as soon as possible after the rash appears. Keeping the immune system healthy is the best way to prevent shingles. Maintaining good hygiene is another way of preventing shingles.

In Genital herpes infection

Genital herpes infection is a common sexually transmitted infection marked by genital pain and sores. It can affect both men and women. Symptoms include pain, itching and irritation. Simavir 250mg Tablet helps in treating the symptoms effectively and also prevents multiplication of the infection causing virus.

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Side effects of Simavir Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Simavir

Headache
Dizziness
Nausea
Rash
Abdominal pain
Itching
Abnormal liver function tests
Increased lipase in the blood
Elevated levels of serum amylase

How to use Simavir Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simavir 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Simavir Tablet works

Simavir 250mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Simavir 250mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Simavir 250mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Simavir 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Simavir 250mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
.

Kidney

CAUTION

Simavir 250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Simavir 250mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Simavir 250mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Simavir 250mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Simavir 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Simavir Tablet?

If you miss a dose of Simavir 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Simavir 250mg Tablet

₹38.0/Tablet

Penvir 250 Tablet

Hetero Drugs Ltd

₹48.17/tablet

27% costlier

Virovir 250 Tablet

FDC Ltd

₹56.5/tablet

49% costlier

Microvir 250 Tablet

Micro Labs Ltd

₹55.33/tablet

46% costlier

Famcimac 250 Tablet

Macleods Pharmaceuticals Pvt Ltd

₹51.5/tablet

36% costlier

Famnova 250mg Tablet

Signova Pharma Pvt Ltd

₹39.5/tablet

4% costlier

View all substitutes

Fact Box

Chemical Class

Nucleoside analog

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral (Non-HIV) drugs

Interaction with drugs

Taking Simavir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Probenecid (Oral Route) Moderate

Probenecid may slow down the removal of Famciclovir through the kidneys. If concurrent use is essential, watch out for symptoms such as sedation, nausea, dizziness, fatigue or con... More

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Oral Route) Moderate

Famciclovir may reduce the efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). Ensure a gap of at least 48 hours after discontinuing Famciclovir before taking ... More

Favipiravir (Oral Route) Mild

Famciclovir may reduce blood levels of Favipiravir. Talk to your doctor if you notice any unusual symptoms.

View all drug interactions

Patient concerns

How to treat Herpes treatment sir?? Its came to me on sonta right side only, please help me sir

Dr. Souvik Sardar

Dermatology

Hello PATIENT a picture.Herpes simplex and herpes zoster r different and have different dosage

Treatment of Herpes and precautions

Dr. Sunil Sekhri

Diabetology

Herpes is of two types Herpes Simplex and Herpes Zooster. Treatment requires correct diagnosis. Let me know your symptoms and if you can send me the clinical findings of your Doctor

FAQs

Does Simavir 250mg Tablet prevent transmission of infection to others?

No, you can infect other people, even while you are being treated with Simavir 250mg Tablet. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.

Is Simavir 250mg Tablet effective?

Simavir 250mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Simavir 250mg Tablet too early, the symptoms may return or worsen.

Can I stop taking Simavir 250mg Tablet when I feel better?

No, do not stop taking Simavir 250mg Tablet without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.

What should I tell my doctor before starting treatment with Simavir 250mg Tablet?

Before starting treatment with Simavir 250mg Tablet, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.

What are the serious side effects of Simavir 250mg Tablet?

Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.

Do elderly patients need to be more careful while taking Simavir 250mg Tablet?

Older adults (over age 65 years) tend to experience more side effects when taking Simavir 250mg Tablet. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Simavir 250mg Tablet, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.

What if I forget to take a dose of Simavir 250mg Tablet?

If you forget a dose of Simavir 250mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

What can happen if somebody takes more than the recommended dose of Simavir 250mg Tablet accidentally?

Accidental, repeated overdoses of oral Simavir 250mg Tablet over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.

Can I get resistant to Simavir 250mg Tablet treatment?

Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Simavir 250mg Tablet. If you are not responding to Simavir 250mg Tablet, the possibility of drug resistance should be checked.

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Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Varicella Zoster IgG

Varicella Zoster IgM

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1601-602.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 847-48.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 531-32.
Famciclovir. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2009 [revised 24 Aug. 2018]. [Accessed 28 Jan. 2019] (online) Available from:
Famciclovir. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1994 [revised Apr. 2013] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

Marketer details

Name: Henry Pharmaceuticals

Address: Devkinandan Basement , Tekdi, Ulhasnagar 1, Mumbai CST Area, Mumbai-400001, Maharashtra, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.