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Signolol 40mg Tablet TR

Propranolol (40mg)

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Signolol 40mg Tablet TR is a medicine used to prevent angina (chest pain) and migraine, and manage pheochromocytoma (a rare adrenal gland tumor). It works by slowing the heart rate and relaxing blood vessels, helping to reduce strain on the heart and improve blood flow.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 26 Aug 2026 | 01:05 AM (IST)

₹35

₹35.06

10 tablet tr

Get by Monday, 31 August

Gurgaon

Payment, Returns & Expiry

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Available

Free Return

within 7 days

Expiry after

Dec, 2028

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General Information

Contains

Propranolol (40mg)

Marketer

Sigmund Promedica

Storage

Store below 30°C

The content is shown in English

Product introduction

Take Signolol 40mg Tablet TR in the dose and duration prescribed by your doctor. It will depend on what you are being treated for and how you respond to the medicine. You should always take it as prescribed by the doctor. It can be taken with or without food. You should keep taking it even if you feel well, as you are still getting the benefits. If you stop taking it suddenly, your condition may worsen.

The most common side effects of Signolol 40mg Tablet TR include tiredness, dizziness, weakness, cold fingers or toes, and stomach pain. You may also experience nausea, vomiting, and diarrhea. Talk to your doctor if the side effects bother you or do not go away. Most side effects are short-lived and improve as your body gets used to the medicine.

You should not use Signolol 40mg Tablet TR if you have asthma, very slow or uneven heartbeats, or a serious heart condition, including heart failure. Talk to your doctor before taking it if you have kidney or liver problems or chronic obstructive pulmonary disease (COPD). In terms of lifestyle, alcohol may affect the way this medicine works and should be avoided. You should not drive if this medicine makes you feel dizzy. Ask your doctor whether it is safe to take this medicine if you are pregnant or breastfeeding.

Uses of Signolol Tablet TR

Prevention of Angina (heart-related chest pain)
Migraine
Treatment of Pheochromocytoma
Arrhythmia
Heart attack
Hypertension (high blood pressure)
Anxiety
Tremors
Glaucoma
Heart Failure
Prevention of migraine

Benefits of Signolol Tablet TR

Prevention of Angina (heart-related chest pain)
Signolol 40mg Tablet TR relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Treatment of Pheochromocytoma
While carrying out surgery for the removal of pheochromocytoma, there is a risk of abnormally high blood pressure. Signolol 40mg Tablet TR blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heartbeat with less force thereby lowering your blood pressure. It is used for the immediate reduction of very high blood pressure (hypertensive emergency). Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.

Prevention of migraine
Signolol 40mg Tablet TR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Side effects of Signolol Tablet TR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Signolol

Nausea
Vomiting
Diarrhea
Abdominal pain
Decreased appetite

How to use Signolol Tablet TR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Signolol 40mg Tablet TR may be taken with or without food.
Avoid Signolol 40mg Tablet TR with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.

How Signolol Tablet TR works

Signolol 40mg Tablet TR contains propranolol, a beta blocker. It works by affecting the body’s response to nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for the heart to pump blood around the body. This prevents arrhythmias. It also widens the blood vessels in the body for better blood flow, thereby preventing angina as well as migraine. Propranolol helps block the effects of the chemical messengers, namely, adrenaline and noradrenaline, that are produced by the brain and are responsible for increasing your heart rate, which makes you feel anxious. This way it helps with anxiety. While treating pheochromocytoma, Signolol 40mg Tablet TR may be given to block the action of high-adrenaline hormones, to lower the risk of developing dangerously high blood pressure during surgery for removing the tumor.

Quick tips

Signolol 40mg Tablet TR may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration, as Signolol 40mg Tablet TR can cause dizziness and sleepiness.
Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain, or sudden shortness of breath, as these may be symptoms of heart failure.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Signolol 40mg Tablet TR.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Signolol 40mg Tablet TR during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Signolol 40mg Tablet TR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Signolol 40mg Tablet TR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Signolol 40mg Tablet TR is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Signolol 40mg Tablet TR should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Signolol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Aminophylline (Oral Route)

Do not consume Aminophylline with Propranolol.

Life-threatening

Theophylline (Oral Route)

Do not use Propranolol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Life-threatening

Theophylline (Injection Route)

Do not use Propranolol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Severe

Arformoterol (Inhalation Route)

Do not use Propranolol with Arformoterol if you have asthma or COPD. Propranolol may reduce efficacy of Arformoterol.

Severe

Bambuterol (Oral Route)

Do not use Propranolol with Bambuterol if you have asthma or COPD. Propranolol may reduce efficacy of Bambuterol.

Frequently asked questions

My doctor has prescribed Signolol 40mg Tablet TR even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?

Yes, it is possible that your doctor prescribed Signolol 40mg Tablet TR for chest pain (angina). Signolol 40mg Tablet TR is a beta-blocker that is used to lower high blood pressure, prevent angina, treat or prevent heart attacks, or reduce your risk of heart problems following a heart attack.

Can Signolol 40mg Tablet TR be used in asthmatics?

No, Signolol 40mg Tablet TR cannot be used in asthmatics. This is because using Signolol 40mg Tablet TR in asthma patients can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any episodes of difficulty breathing, before starting treatment with Signolol 40mg Tablet TR.

Can I stop taking Signolol 40mg Tablet TR as my chest pain is under control?

No, you should not stop taking Signolol 40mg Tablet TR suddenly because that may worsen your angina or may cause a heart attack. Tell your doctor, and if there is a need to stop Signolol 40mg Tablet TR, your doctor will reduce your dose gradually over a few weeks.

Does Signolol 40mg Tablet TR relieve anxiety?

Yes, Signolol 40mg Tablet TR helps relieve the symptoms of anxiety such as irritability, restlessness, excessive worry, lack of concentration, racing or unwanted thoughts, fatigue, insomnia (lack of sleep), palpitations (irregular heart rate), or trembling. The dose and duration of taking Signolol 40mg Tablet TR will be suggested by your doctor, depending on whether your symptoms are a recurring problem or occur only in stressful conditions. However, Signolol 40mg Tablet TR is usually given for the short-term treatment of anxiety. If you have any doubts, consult your doctor.

What other lifestyle changes should I make while taking Signolol 40mg Tablet TR?

Lifestyle changes play a major role in keeping you healthy if you are taking Signolol 40mg Tablet TR. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation, or take up a hobby. Ensure that you have a sound sleep every night, as this also helps reduce stress levels and helps keep your blood pressure normal.

Stop smoking and alcohol consumption, as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and eat a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Signolol 40mg Tablet TR and to keep yourself healthy.

I have been on Indomethacin for several months. Will it be a problem if I start taking Signolol 40mg Tablet TR along with it?

Yes, indomethacin may interfere with the working of Signolol 40mg Tablet TR and make it less effective. As a result, your blood pressure may increase. Speak to your doctor, who will prescribe you a different medicine to control blood pressure.

Fact Box

Chemical Class

Naphthalene derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Non-Selective Beta-Blockers (NSBBs)

Related lab tests

Kidney Function Test

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 320.
Opie LH. β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 28-29.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 175-76.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1162-63.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
National Health Service: Propranolol [Drug Information]. 2024. [Accessed 17 Mar. 2025] (online) Available from:

User feedback

Patients taking Signolol 40mg Tablet TR

Once A Day

89%

Twice A Day

11%

What are you using Signolol Tablet TR for?

Anxiety

57%

Migraine

29%

Heart attack

14%

How much was the improvement?

Average

67%

Poor

33%

What were the side-effects while using Signolol 40mg Tablet TR?

Fatigue

20%

Headache

20%

Dizziness

20%

Constipation

20%

No Side Effect

20%

How do you take Signolol Tablet TR?

With food

50%

With or without food

50%

Please rate Signolol 40mg Tablet TR on price

Not Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sigmund Promedica
Address: 30-22-118, First Floor, Eluru Road,Seetharampuram,Vijayawada 520 002,Andhra Pradesh

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Signolol 40mg Tablet TR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Home

Cardiac

Beta Blocking Agents Plain

Signolol 40mg Tablet TR

Signolol 40mg Tablet TR

Payment, Returns & Expiry

Cash on delivery

Free Return

Expiry after

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Signolol Tablet TR

Benefits of Signolol Tablet TR

Side effects of Signolol Tablet TR

How to use Signolol Tablet TR

How Signolol Tablet TR works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Theophylline (Oral Route)

Theophylline (Injection Route)

Arformoterol (Inhalation Route)

Bambuterol (Oral Route)

Frequently asked questions

My doctor has prescribed Signolol 40mg Tablet TR even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?

Can Signolol 40mg Tablet TR be used in asthmatics?

Can I stop taking Signolol 40mg Tablet TR as my chest pain is under control?

Does Signolol 40mg Tablet TR relieve anxiety?

What other lifestyle changes should I make while taking Signolol 40mg Tablet TR?

I have been on Indomethacin for several months. Will it be a problem if I start taking Signolol 40mg Tablet TR along with it?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Signolol 40mg Tablet TR

What are you using Signolol Tablet TR for?

How much was the improvement?

What were the side-effects while using Signolol 40mg Tablet TR?

How do you take Signolol Tablet TR?

Please rate Signolol 40mg Tablet TR on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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