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Scool 50 Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 22 Jan 2026 | 03:21 PM (IST)
Scool 50 Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It is also used to treat bipolar disorders.
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Scool 50 Tablet
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General Information

The content is shown in English
Scool 50 Tablet image
Scool 50 Tablet image

Product introduction

Scool 50 Tablet may be taken without food or with light meals. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness or seizures.

Some common side effects of this medicine include decreased hemoglobin levels in the blood, increased triglycerides level in blood, decreased cholesterol level in blood, headache, extrapyramidal symptoms, dry mouth, and withdrawal symptoms. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

You should be cautious while using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Benefits of Scool Tablet

Treatment of Mania
Mania means extremely excited or elevated mood. Scool 50 Tablet helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Scool 50 Tablet will ensure that you have a better social life and are able to do daily activities more comfortably.
Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Scool 50 Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Scool Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Scool
  • Dizziness
  • Constipation
  • High blood pressure
  • Fatigue
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dryness in mouth
  • Dyslipidemia
  • Sleepiness

How to use Scool Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Scool 50 Tablet is to be taken on an empty stomach.

How Scool Tablet works

Scool 50 Tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Quick tips

  • You have been prescribed Scool 50 Tablet for the treatment of schizophrenia and mania.
  • It is less likely to cause heart problems and movement disorders than other antipsychotics.
  • It may take 4 to 6 weeks to see treatment effects. Keep taking it as prescribed.
  • Use caution while driving or doing anything that requires concentration as Scool 50 Tablet can cause dizziness and sleepiness.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking it without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Scool 50 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Scool 50 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Scool 50 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Scool 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Scool 50 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Scool 50 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Scool with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Quetiapine.
Life-threatening

Dronedarone (Oral Route)

Do not consume Dronedarone with Quetiapine. If concurrent use is essential, watch out for symptoms of Quetiapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Quetiapine accordingly. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Pimozide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Quetiapine.

Frequently asked questions

Scool 50 Tablet helps to correct chemical imbalances in the brain. It acts on various chemical messengers in the brain like dopamine and serotonin. It prevents the excessive activity of dopamine, helping to treat symptoms of schizophrenia and mania.
Scool 50 Tablet can make you feel sleepy, but it is not used as a sleeping pill. Scool 50 Tablet is approved for the treatment of symptoms of schizophrenia. It prevents as well as treats episodes of mania and depression in bipolar disorder. It is also used with other medicines to treat depression.
You may start seeing an improvement within a week of starting Scool 50 Tablet but full benefits may take about 4-6 weeks to appear.
Scool 50 Tablet has not been approved for the treatment of anxiety; however, your doctor may prescribe it for anxiety. Some studies suggest its use in post-traumatic stress disorder, generalized anxiety disorder, and anxiety associated with mood disorders.
Scool 50 Tablet can cause drowsiness. So, do not drive, operate machinery or do anything dangerous until you know how Scool 50 Tablet affects you. Do not drink alcohol while taking Scool 50 Tablet as it may worsen the drowsiness. Avoid getting dehydrated or over-exposure to heat.
No, you should not stop taking Scool 50 Tablet without consulting your doctor. Suddenly stopping it may cause nausea, vomiting, headache, diarrhea, dizziness, irritability and inability to sleep. If you feel better, consult your doctor who will gradually reduce the dose before completely stopping it.
Yes, weight gain is a common side effect of Scool 50 Tablet. If you feel you are gaining weight, consult your doctor or a nutritionist who will suggest you a diet and some exercise to help you manage your weight.
Take Scool 50 Tablet exactly as advised by your doctor. Do not split, chew or crush the tablets. Swallow the tablet whole with a glass of water. Do not take it with food. It is advised to take this medicine for at least one hour before a meal or at bedtime. Do not take grapefruit while taking Scool 50 Tablet as it may affect the working of this medicine.
Scool 50 Tablet helps to correct chemical imbalances in the brain. It acts on various chemical messengers in the brain like dopamine and serotonin. It prevents the excessive activity of dopamine, helping to treat symptoms of schizophrenia and mania.
Scool 50 Tablet can make you feel sleepy, but it is not used as a sleeping pill. Scool 50 Tablet is approved for the treatment of symptoms of schizophrenia. It prevents as well as treats episodes of mania and depression in bipolar disorder. It is also used with other medicines to treat depression.
You may start seeing an improvement within a week of starting Scool 50 Tablet but full benefits may take about 4-6 weeks to appear.
Scool 50 Tablet has not been approved for the treatment of anxiety; however, your doctor may prescribe it for anxiety. Some studies suggest its use in post-traumatic stress disorder, generalized anxiety disorder, and anxiety associated with mood disorders.
Scool 50 Tablet can cause drowsiness. So, do not drive, operate machinery or do anything dangerous until you know how Scool 50 Tablet affects you. Do not drink alcohol while taking Scool 50 Tablet as it may worsen the drowsiness. Avoid getting dehydrated or over-exposure to heat.
No, you should not stop taking Scool 50 Tablet without consulting your doctor. Suddenly stopping it may cause nausea, vomiting, headache, diarrhea, dizziness, irritability and inability to sleep. If you feel better, consult your doctor who will gradually reduce the dose before completely stopping it.
Yes, weight gain is a common side effect of Scool 50 Tablet. If you feel you are gaining weight, consult your doctor or a nutritionist who will suggest you a diet and some exercise to help you manage your weight.
Take Scool 50 Tablet exactly as advised by your doctor. Do not split, chew or crush the tablets. Swallow the tablet whole with a glass of water. Do not take it with food. It is advised to take this medicine for at least one hour before a meal or at bedtime. Do not take grapefruit while taking Scool 50 Tablet as it may affect the working of this medicine.

Fact Box

Chemical Class

Dibenzothiazepines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Name: Shatayushi Healthcare Pvt Ltd
Address: arvinda ghosh marg, ramdaspeth, akola, maharashtra 444001

Vendor Details

Country of origin: India
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