Saglipol 2.5 Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Saglipol 2.5 Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.

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Saxagliptin (2.5mg)

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General Information

Contains

Saxagliptin (2.5mg)

Marketer

Medipol Pharmaceuticals India Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Saglipol Tablet

Type 2 diabetes mellitus

Benefits of Saglipol Tablet

Type 2 diabetes mellitus
Saglipol 2.5 Tablet belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It helps increase the amount of insulin your body produces after a meal and to stop your body releasing too much glucose (sugar) into your blood. This way it lowers the blood glucose levels in your body. It is usually taken once a day and has relatively few common side effects.
Lowering blood glucose levels is an essential part of managing diabetes. Controling the blood glucose level helps prevent serious complications of diabetes such as kidney damage, blindness, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed for long-term benefits.

Side effects of Saglipol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Saglipol

Peripheral edema
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
Upper respiratory tract infection
Urinary tract infection
Headache

How to use Saglipol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Saglipol 2.5 Tablet may be taken with or without food.

How Saglipol Tablet works

Saglipol 2.5 Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

All substitutes for Saglipol 2.5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Onglyza 2.5mg Tablet

by AstraZeneca

₹41.07/tablet

26% costlier

Zaxaglit 2.5mg Tablet

by Chemo Healthcare Pvt Ltd

₹33.4/tablet

3% costlier

Quick tips

Saglipol 2.5 Tablet should be taken at the same time every day since this helps you remember to take it.
Be careful while driving or operating machinery until you know how Saglipol 2.5 Tablet affects you.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Saglipol 2.5 Tablet

Pregnancy

SAFE IF PRESCRIBED

Saglipol 2.5 Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Saglipol 2.5 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CAUTION

Saglipol 2.5 Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

Kidney

CAUTION

Saglipol 2.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is recommended for dose adjustment.

Liver

SAFE IF PRESCRIBED

Saglipol 2.5 Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Saglipol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Moderate

Amisulpride (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Saxagliptin.

Moderate

Amisulpride (Injection Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Saxagliptin.

Moderate

Aripiprazole (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Aripiprazole may reduce the efficacy of Saxagliptin.

Frequently asked questions

Does Saglipol 2.5 Tablet cause any weight loss (reduction)?

No, Saglipol 2.5 Tablet neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Saglipol 2.5 Tablet is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.

What is the benefit of using Saglipol 2.5 Tablet with insulin?

Saglipol 2.5 Tablet when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.

Are there any contraindications to the use of Saglipol 2.5 Tablet?

Yes, the use of Saglipol 2.5 Tablet is contraindicated in some conditions like a history of allergy to Saglipol 2.5 Tablet, any ingredients of this drug or to any other drug of the same class. Saglipol 2.5 Tablet should also be avoided in patients with a history of pancreatitis.

Is it beneficial to use Saglipol 2.5 Tablet with glipizide?

Yes, it is beneficial to take Saglipol 2.5 Tablet and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.

Can Saglipol 2.5 Tablet be used with other diabetes medicines?

Yes, Saglipol 2.5 Tablet can be used alone or in combination with other diabetes medicines, along with proper diet and exercise.

Can the use of Saglipol 2.5 Tablet cause hypoglycemia (low blood sugar)?

Usually, Saglipol 2.5 Tablet does not cause hypoglycemia when used alone in diabetes. However, it may cause low blood sugar when combined with other medicines like insulin and sulfonylureas.

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1264.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1248-49.
Saxagliptin. Princeton, New Jersey: Bristol-Myers Squibb Company; 2009. [Accessed 12 Mar. 2019] (online) Available from:
Saxagliptin. Macclesfield, Cheshire: AstraZeneca UK Limited; 2018. [Accessed 12 Mar. 2019] (online) Available from:
Saxagliptin [Summary of Product Characteristics]. Södertälje, Sweden; AstraZeneca AB. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [FDA Prescribing Information]. Wilmington, DE; AstraZeneca Pharmaceuticals LP; 2015. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [EMC Label]. Luton, UK; AstraZeneca UK Limited; 2021. [Accessed 09 Feb. 2022] (online) Available from:
Saxagliptin [Prescribing Informataion]. Princeton, NJ: Bristol-Myers Squibb Company; 2009. [Accessed 20 Feb. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medipol Pharmaceuticals India Pvt Ltd
Address: 128/5, Swiss House, Vishwas Nagar, Delhi 110032 Delhi, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Saglipol 2.5 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Saglipol Tablet

Benefits of Saglipol Tablet

Side effects of Saglipol Tablet

How to use Saglipol Tablet

How Saglipol Tablet works

All substitutes for Saglipol 2.5 Tablet

Onglyza 2.5mg Tablet

Zaxaglit 2.5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Asparaginase (Injection Route)

Amisulpride (Oral Route)

Amisulpride (Injection Route)

Aripiprazole (Oral Route)

Frequently asked questions

Does Saglipol 2.5 Tablet cause any weight loss (reduction)?

What is the benefit of using Saglipol 2.5 Tablet with insulin?

Are there any contraindications to the use of Saglipol 2.5 Tablet?

Is it beneficial to use Saglipol 2.5 Tablet with glipizide?

Can Saglipol 2.5 Tablet be used with other diabetes medicines?

Can the use of Saglipol 2.5 Tablet cause hypoglycemia (low blood sugar)?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests