Rofiplag 5mg Injection

Tirofiban (5mg)

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Rofiplag 5mg Injection is a blood thinner which prevents formation of harmful blood clots. It helps to prevent a heart attack in patients presenting with severe chest pain due to a sudden decrease in blood flow to the heart.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Apr 2026 | 04:05 PM (IST)

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General Information

Contains

Tirofiban (5mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Rofiplag 5mg Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long term treatment even after this injection.

Common side effects of this medicine include headaches, hematoma, nausea, ecchymosis, postoperative bleeding, and blood in stool or urine. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool.

This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are breastfeeding and about all the other medications that you are taking regularly.

Uses of Rofiplag Injection

Prevention of Heart attack
Unstable angina

Benefits of Rofiplag Injection

Prevention of Heart attack
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

Side effects of Rofiplag Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rofiplag

Headache
Nausea
Hematoma
Ecchymosis (discoloration of the skin resulting from bleeding underneath)
Postoperative bleeding
Blood in stool
Blood in urine

How to use Rofiplag Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Rofiplag Injection works

Rofiplag 5mg Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Quick tips

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Rofiplag 5mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Rofiplag 5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Rofiplag 5mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Rofiplag 5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Rofiplag 5mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Rofiplag 5mg Injection is unsafe to use in patients with liver disease and should be avoided.
Use of Rofiplag 5mg Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Rofiplag with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Tirofiban. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Moderate

Ticagrelor (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Moderate

Rivaroxaban (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Aceclofenac (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Aceclofenac (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Can the use of Rofiplag 5mg Injection increase the risk of bleeding?

Yes, Rofiplag 5mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

What medicines should I avoid while taking Rofiplag 5mg Injection?

Rofiplag 5mg Injection can interact with several medicines. Do not take any medicine without talking to your doctor.

When will I feel better after taking Rofiplag 5mg Injection?

Rofiplag 5mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Rofiplag 5mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Fact Box

Chemical Class

Phenylalanine derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Glycoprotein IIb/IIIa Inhibitors

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 871-72.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 355.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1369-70.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Tirofiban hydrochloride monohydrate. Uxbridge, UK: Correvio UK Ltd.; 1999 [03 Dec. 2014]. [Accessed 24 Jan. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Rofiplag 5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Rofiplag 5mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Rofiplag Injection

Benefits of Rofiplag Injection

Side effects of Rofiplag Injection

How to use Rofiplag Injection

How Rofiplag Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apixaban (Oral Route)

Ticagrelor (Oral Route)

Rivaroxaban (Oral Route)

Aceclofenac (Oral Route)

Aceclofenac (Injection Route)

Frequently asked questions

Can the use of Rofiplag 5mg Injection increase the risk of bleeding?

What medicines should I avoid while taking Rofiplag 5mg Injection?

When will I feel better after taking Rofiplag 5mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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