RIZact 5 MD Tablet

Rizatriptan (5mg)

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required

RIZact 5 MD Tablet is used in the treatment of acute attacks of migraine. It relieves the symptoms of migraine and prevents the attack from becoming worse. This medicine helps by narrowing the blood vessels, thereby relieving migraine headaches.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 May 2026 | 05:59 PM (IST)

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General Information

Contains

Rizatriptan (5mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

RIZact 5 MD Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better and if you have missed a dose, take it as soon as you remember. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly.

Side effects associated with the use of this medicine include dry mouth, sensation of heaviness, nausea, weakness, and paresthesia (tingling or pricking sensation). However, these are usually temporary and usually resolve on their own. Please consult your doctor if these do not subside or worry you.

It may also cause sleepiness at the beginning of your treatment, so do not drive, operate machinery, until you know how this medicine affects you. This medicine may cause changes in your mood and you may feel depressed, therefore, regular monitoring of behavior is important. Pregnant or breastfeeding mothers should consult their doctor before taking this medicine.

Inform your doctor if you are suffering from any heart problems, as the use of RIZact 5 MD Tablet is contraindicated in some heart diseases. Regular monitoring of blood pressure is required while taking this medicine. Consult your doctor and stop this medicine if you develop severe chest or stomach pain, bloody diarrhea, or significantly high blood pressure, after taking this medicine.

Uses of RIZact Tablet MD

Acute migraine headache

Benefits of RIZact Tablet MD

Acute migraine headache
Migraine is a type of headache that causes intense throbbing pain, often with nausea and sensitivity to light or sound. RIZact 5 MD Tablet is used during a migraine attack to relieve headache, ease associated symptoms, and help patients return to normal activities faster.

Side effects of RIZact Tablet MD

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of RIZact

Dizziness
Dryness in mouth
Heaviness
Nausea
Sleepiness
Weakness

How to use RIZact Tablet MD

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. RIZact 5 MD Tablet may be taken with or without food.

How RIZact Tablet MD works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. RIZact 5 MD Tablet works by constricting (narrowing) these blood vessels, thereby relieving the migraine headaches.

Quick tips

You have been prescribed RIZact 5 MD Tablet for treatment of migraine headaches.
Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get enough sleep and avoid stress
It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Notify your doctor if your migraine occurs more often after starting the medication.
Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
Inform your doctor if you have a history of heart disease or stroke.
This medication does not prevent migraine attacks from happening.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with RIZact 5 MD Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

RIZact 5 MD Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of RIZact 5 MD Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

RIZact 5 MD Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

RIZact 5 MD Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of RIZact 5 MD Tablet in patients with liver disease.

Interaction with drugs

Taking RIZact with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Selegiline (Oral Route)

Do not consume Rizatriptan with Selegiline. If Rizatriptan is essential, ensure a gap of at least 24 hours after discontinuing Selegiline. Please consult your doctor.

Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.

Life-threatening

Tranylcypromine (Oral Route)

Tranylcypromine may raise blood levels of Rizatriptan. Tranylcypromine may raise blood levels of Rizatriptan.

Severe

Ziprasidone (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines accordingly.

Severe

Linezolid (Oral Route)

Do not consume Linezolid with Rizatriptan. If concurrent use is essential, watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them.

Frequently asked questions

What should I tell my doctor before taking RIZact 5 MD Tablet?

Before taking RIZact 5 MD Tablet, you should tell your doctor if you have heart disease, high blood pressure, diabetes, liver or kidney disease or a family history of heart disease. You should also inform your doctor if you smoke, have had your menopause, or are a man aged 40 years or more. Let your doctor know if your headache is associated with dizziness, difficulty in walking, lack of coordination or weakness in the leg and arm. Your doctor should also know if you are taking medicines to treat depression such as sertraline, escitalopram oxalate, fluoxetine, venlafaxine, or duloxetine. It is also important to inform your doctor if you have had short-lived chest pain and tightness.

What are the symptoms of RIZact 5 MD Tablet overdose?

Taking an overdose of RIZact 5 MD Tablet may cause fainting, dizziness, slow heartbeat, change in electrical activity of the heart, vomiting and inability to retain urine or stools.

What are the symptoms of headache caused due to medication overuse?

If you are having frequent or daily headaches despite (or because of) the regular use of headache medications, it is suggestive of medication overuse headache. You should consult your doctor who may discontinue the medication for sometime.

Can RIZact 5 MD Tablet be used for the prevention of migraine attacks?

No, RIZact 5 MD Tablet is not used for the prevention of migraine attacks. It should only be used where a clear diagnosis of migraine has been established.

What triggers migraine attacks?

Migraine may be triggered by several factors. Some of the common triggers are caffeine withdrawal, changes in hormone levels during menstruation or with the use of birth control pills. Migraine also gets triggered with changes in sleep patterns, such as not getting enough sleep, drinking alcohol, missing meals, or smoking. Rigorous exercise or other physical stress, loud noises or bright lights, odors or perfumes, or exposure to smoke and stress and anxiety may also act as a trigger.

Does migraine run in families?

Migraines may run in families. Migraines occur more often in women than men. It has been noticed that some women, but not all, have fewer migraines when they are pregnant.

Can RIZact 5 MD Tablet increase my blood pressure?

Yes, RIZact 5 MD Tablet can cause an increase in blood pressure. However, it is does not occur in everyone. But, you should keep a check on your blood pressure during therapy with RIZact 5 MD Tablet.

How do I know migraine attack is about to start?

Some people develop aura before getting a migraine attack. It may include visual problems, such as seeing flashing lights, zig-zag patterns or blind spots, numbness, dizziness, or a tingling sensation like pins and needles, or feeling off balance. You may also have difficulty speaking and loss of consciousness, although this is unusual.

Can I take RIZact 5 MD Tablet with propranolol?

Yes, you can take propranolol and RIZact 5 MD Tablet together. However, since Propranolol may cause an increase in levels of RIZact 5 MD Tablet, so you should take 5 mg dose of RIZact 5 MD Tablet and not 10 mg.

When should I start taking the medicines used to prevent migraine?

Medicines for prevention of migraine are usually used if you have tried avoiding possible triggers but are still experiencing migraines. You may also be prescribed these medicines if you experience very severe migraine attacks, or if your attacks happen frequently.

Can RIZact 5 MD Tablet cause liver damage?

No, RIZact 5 MD Tablet does not cause liver damage, but you should let your doctor know if you have any liver problem, before taking RIZact 5 MD Tablet.

How soon should I take RIZact 5 MD Tablet when attack starts?

Once your migraine headache has started, take RIZact 5 MD Tablet as soon as possible. Do not use it to prevent an attack. Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Fact Box

Chemical Class

Tryptamine derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Triptans (5-HT1B/1D Agonists)

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1229-30.
Rizatriptan. Haarlem, The Netherlands: MERCK SHARP & DOHME B.V; 2018. [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rizatriptan. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Rizatriptan benzoate [Product Label]. Whitehouse Station, NJ: Merck & CO., Inc.; 2007. [Accessed 20 Feb. 2024] (online) Available from:
Rizatriptan benzoate [Product Label]. Hyderabad, Telangana: Aurobindo Pharma Ltd.; 2025. [Accessed 06 Nov. 2025] (online). Available from:

User feedback

Patients taking RIZact 5 MD Tablet

Once A Day

93%

Twice A Day

Twice A Week

What are you using RIZact Tablet MD for?

Acute migraine headache

88%

Others

12%

How much was the improvement?

Excellent

48%

Average

38%

Poor

14%

What were the side-effects while using RIZact 5 MD Tablet?

No Side Effect

40%

Dizziness

30%

Sleepiness

20%

Dryness in mouth

10%

How do you take RIZact Tablet MD?

With or without food

67%

With food

33%

Please rate RIZact 5 MD Tablet on price

Average

44%

Not Expensive

28%

Expensive

28%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Neuro Cns

Anti Migraine Preparations

RIZact 5 MD Tablet

RIZact 5 MD Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of RIZact Tablet MD

Benefits of RIZact Tablet MD

Side effects of RIZact Tablet MD

How to use RIZact Tablet MD

How RIZact Tablet MD works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Selegiline (Oral Route)

Tapentadol (Nasal Route)

Tranylcypromine (Oral Route)

Ziprasidone (Oral Route)

Linezolid (Oral Route)

Frequently asked questions

What should I tell my doctor before taking RIZact 5 MD Tablet?

What are the symptoms of RIZact 5 MD Tablet overdose?

What are the symptoms of headache caused due to medication overuse?

Can RIZact 5 MD Tablet be used for the prevention of migraine attacks?

What triggers migraine attacks?

Does migraine run in families?

Can RIZact 5 MD Tablet increase my blood pressure?

How do I know migraine attack is about to start?

Can I take RIZact 5 MD Tablet with propranolol?

When should I start taking the medicines used to prevent migraine?

Can RIZact 5 MD Tablet cause liver damage?

How soon should I take RIZact 5 MD Tablet when attack starts?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking RIZact 5 MD Tablet

What are you using RIZact Tablet MD for?

How much was the improvement?

What were the side-effects while using RIZact 5 MD Tablet?

How do you take RIZact Tablet MD?

Please rate RIZact 5 MD Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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