Author Details
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
29 Nov 2023 | 06:59 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Rifaxia 400 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Rifaxia 400 Tablet is an antibiotic that treats hepatic encephalopathy, a condition in which the liver fails to remove harmful toxins from the blood, leading to brain damage. It is also used to treat infectious diarrhea. It works by killing and stopping the growth of harmful bacteria in the intestines.

This medicine can be used alone or in combination with other medicines. It may be taken with or without food, preferably at the same time, each day. It should be used in the dose and duration as advised by the doctor. Take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like vomiting, headache, dizziness, nausea, rashes, joint pain, and depression. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away. Your urine may become reddish in color due to this medicine. But, it is normal and harmless.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine.

Uses of Rifaxia Tablet

  • Treatment of Hepatic encephalopathy
  • Treatment of Infectious diarrhea

Benefits of Rifaxia Tablet

In Treatment of Hepatic encephalopathy

Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems and loss of consciousness. Symptoms include agitation, confusion, muscle problems, difficulty in speaking, and sometimes, coma. Rifaxia 400 Tablet lowers the levels of ammonia-producing bacteria in the blood which has harmful effects on the brain. If taken as prescribed, this medicine can improve your brain function and reduce symptoms associated with hepatic encephalopathy.

In Treatment of Infectious diarrhea

Infectious diarrhea is a condition characterized by the sudden onset of loose or watery stools caused by harmful microorganisms in the digestive system. Rifaxia 400 Tablet helps treat infectious diarrhea by targeting and stopping the growth of harmful bacteria in the intestines. This medicine interferes with the bacteria's ability to make important proteins they need to survive and multiply. This helps to get rid of the bad bacteria causing the infection, which in turn reduces the diarrhea and helps you feel better.

Side effects of Rifaxia Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rifaxia

  • Dizziness
  • Nausea
  • Peripheral edema
  • Ascites (accumulation of fluid in the abdominal cavity)
  • Fatigue
  • Depression
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Joint pain
  • Rash
  • Muscle pain

How to use Rifaxia Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifaxia 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Rifaxia Tablet works

Rifaxia 400 Tablet is an antibiotic. It works by killing the ammonia-producing bacteria in the digestive tract. This treats your infection and relieves symptoms of hepatic encephalopathy (agitation, confusion, muscle problems). This also helps reduce the recurrence of episodes of hepatic encephalopathy.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rifaxia 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Rifaxia 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Rifaxia 400 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Rifaxia 400 Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Rifaxia 400 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rifaxia 400 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Rifaxia 400 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Rifaxia 400 Tablet may be needed. Please consult your doctor.

What if you forget to take Rifaxia Tablet?

If you miss a dose of Rifaxia 400 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Rifaxia 400 Tablet
₹29.4/Tablet
Rexigut 400mg Tablet
Leeford Healthcare Ltd
₹28.5/tablet
3% cheaper
₹37.1/tablet
26% costlier
Rifamycid 400mg Tablet
German Remedies
₹37.9/tablet
29% costlier
Rifagut 400 Tablet
Sun Pharmaceutical Industries Ltd
₹37.9/tablet
29% costlier
₹45.5/tablet
55% costlier

Quick tips

  • Rifaxia 400 Tablet reduces the risk of overt hepatic encephalopathy (HE) recurrence in patients with liver disease.
  • It may cause reddish discoloration of urine. This is normal and harmless.
  • Stop taking Rifaxia 400 Tablet and inform your doctor if you have severe diarrhea during or after using Rifaxia 400 Tablet.
  • Finish the full course of the medication, even if you feel better.

Fact Box

Chemical Class
Rifamycin derivatives
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
RNA polymerase inhibitors- Rifamycins

Patient concerns

arrow
hepatic encephalopathy fro 12 October
Dr. Saurav Arora
Homeopathy
Dear sir as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.
Jaundice liver cirrhosis. Hepatic encephalopathy and ascites not edema with Sodium 107. Can we use tolvaptone?
Dr. Gurpreet Singh
Physician
Sir consult a hepatologist
arrow

FAQs

Q. Should I take Rifaxia 400 Tablet with food?

Yes, Rifaxia 400 Tablet can be taken orally with or without food with a glass of water. Take it as prescribed by your doctor for the exact period of time.

Q. What does Rifaxia 400 Tablet do for the liver?

In liver disease, there is an increased growth of bacteria in the intestine which increases the load of toxins travelling through the body. This further increases the possibility of toxins reaching the brain which can cause abnormal brain function. Rifaxia 400 Tablet slows down the growth of bacteria in the gut, decreasing the symptoms in cases of liver disease.

Q. Can Rifaxia 400 Tablet cause weight gain?

Usually Rifaxia 400 Tablet does not cause weight gain. However, in case you feel there is an increase in weight, you should consult your doctor to determine the reason of weight gain.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1215-16.
  2. Rifaximin [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2015. [Accessed 05 Aug. 2023] (online) Available from:External Link
  3. CiplaMed. Rifaximin [Prescribing Information]. [Accessed 05 Aug. 2023] (online) Available from:External Link

Marketer details

Name: Chemo Biological
Address: Chemo Biological, A-50, G. T. Karnal Road, Industrial Area, Near Azadpur Metro Station, Opposite Hans Cinema, Delhi - 110033, India
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

294
Inclusive of all taxes
MRP310  5% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me
Available options
Available options
Same salt composition:Rifaximin (400mg)
https://onemg.gumlet.io/epf1dtoymcv3sbkzuspl.png
Same salt composition
https://onemg.gumlet.io/qkdhgo7ram1mle08cya9.png
Verified by doctors
https://onemg.gumlet.io/ehvn8wef9oaoewteak8d.png
Popularly bought
https://onemg.gumlet.io/xnv1s7snefeql2hkalfr.png
Trusted quality
Why buy these from 1mg?question-mark

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.