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Regubeat 100mg Tablet

Disopyramide (100mg)
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Regubeat 100mg Tablet is a medicine used to treat arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. This helps to maintain a regular and steady heartbeat.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 27 Aug 2026 | 01:03 AM (IST)
₹33 MRP ₹35.838% off 
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Regubeat 100mg Tablet image
Regubeat 100mg Tablet image

Product introduction

Regubeat 100mg Tablet should be taken regularly as advised by the doctor. You may take it without food, but it is better to take this medicine at a fixed time. This medicine should not be stopped abruptly without consulting the doctor, as this can worsen your condition. Regular follow-up with your doctor is advised while using this medicine.


Side effects like constipation, dryness in the mouth, urinary retention, and blurred vision may be seen in some patients. This medicine may also lead to worsening of heart function and low blood pressure in patients with preexisting heart disease. Your doctor may advise regular monitoring of blood sugar levels and kidney function while you are taking this medicine.


This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any heart, liver, or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it.

Uses of Regubeat Tablet

Benefits of Regubeat Tablet

Arrhythmia
Arrhythmia is a condition in which the heart beats irregularly, too fast, or too slow, which can affect blood flow and increase the risk of complications. Regubeat 100mg Tablet helps restore a normal heart rhythm, ensuring that the heart pumps blood properly. This improves overall heart function and reduces symptoms such as palpitations, dizziness, and shortness of breath.

Side effects of Regubeat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Regubeat
  • Constipation
  • Dryness in mouth
  • Urinary hesitancy

How to use Regubeat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Regubeat 100mg Tablet is to be taken on an empty stomach.

How Regubeat Tablet works

Regubeat 100mg Tablet is an anti-arrhythmic medication. It works by blocking abnormal electrical signals in the heart to correct an irregular heartbeat to a normal rhythm.

Quick tips

  • Regubeat 100mg Tablet may cause dizziness. Do not drive or perform activities that require mental focus until you know how it affects you.
  • Do not start any medicine, including prescription or over-the-counter medicine, without informing your doctor, as they may alter Regubeat 100mg Tablet levels in your body.
  • Your doctor may get blood tests done to check your sodium and potassium levels, kidney function, and lung function before starting treatment with this medicine.
  • Your doctor may regularly monitor your blood sugar level while you are taking this medicine.
  • Inform your doctor if you experience a slow or fast heart rate, chest pain, or shortness of breath.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Regubeat 100mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Regubeat 100mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Regubeat 100mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Regubeat 100mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Regubeat 100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Regubeat 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Regubeat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Disopyramide. If concurrent use is essential, please consult your doctor.
Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Disopyramide.
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Disopyramide.
Life-threatening

Fluconazole (Oral Route)

Do not consume Fluconazole with Disopyramide.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Disopyramide.

Frequently asked questions

Regubeat 100mg Tablet is a medicine used to treat serious types of irregular heartbeats (called ventricular arrhythmias). These are heart rhythm problems that start in the lower chambers of your heart and can be life-threatening if not treated.
Individuals should not take Regubeat 100mg Tablet if they have cardiogenic shock (a condition where the heart suddenly can't pump enough blood to meet the body’s needs). It should also be avoided in those with second- or third-degree heart block without a pacemaker (a problem with the heart’s electrical signals), or congenital QT syndrome (a genetic condition that affects heart rhythm). Additionally, anyone allergic to disopyramide or any other ingredients in Regubeat 100mg Tablet should not use it.
You should call your doctor right away if you experience serious side effects of Regubeat 100mg Tablet. These may include low blood pressure, a very fast or slow heartbeat (which could indicate a dangerous heart rhythm), or trouble urinating (a possible sign of urinary blockage). Other symptoms include dry mouth, blurred vision, or constipation, which may result from anticholinergic side effects—when a drug blocks certain nerve signals. Watch for signs of heart failure as well, such as swelling in the legs, shortness of breath, or sudden weight gain.
Yes, Regubeat 100mg Tablet may cause low blood sugar (hypoglycemia), especially in people with diabetes. Symptoms include sweating, shakiness, confusion, and feeling very hungry. If you have diabetes, check your blood sugar regularly and talk to your doctor about adjusting your medication.
Before starting Regubeat 100mg Tablet, you should tell your doctor if you have any heart condition (especially heart block, heart failure, or history of arrhythmia), diabetes, glaucoma (eye condition with high pressure), enlarged prostate or trouble urinating, and kidney or liver problems. This helps your doctor decide if Regubeat 100mg Tablet is safe for you.
Your doctor may advise you a follow-up for a proper health assessment. However, you may perform daily checks such as pulse rate/regularity, weight (for fluid retention), urine output and blood pressure. Report it to the doctor in case of any fluctuation.
Yes, Regubeat 100mg Tablet may cause dry mouth in some individuals. Dry mouth is a common side effect of Regubeat 100mg Tablet. You may try candy or chewing gum to manage excessive dry mouth.
No, never stop taking Regubeat 100mg Tablet on your own as it may worsen the condition. Your doctor may assess your response to the Regubeat 100mg Tablet and severity of the condition and may taper the dose of Regubeat 100mg Tablet. Typical tapering of dose over 2-4 weeks with continuous cardiac monitoring is essential.
Yes, Regubeat 100mg Tablet may cause low blood pressure. Low blood pressure (hypotension) is the most common side effect of Regubeat 100mg Tablet treatment. Your doctor may monitor your blood pressure closely and may advise you to do so.
Yes, Regubeat 100mg Tablet may cause constipation. Constipation is a common side effect of Regubeat 100mg Tablet. You may include a fibre-rich diet to manage constipation. However, if this side effect bothers your well-being, ask your doctor for specific treatment.

Fact Box

Chemical Class

Pheniramines

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Class I Antiarrhythmics

References

  1. Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 839.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 419-20.
  3. Hume JR, Grant AO. Agents used in cardiac arrhythmias: Disopyramide (Subgroup 1A). In: Katzung BG, masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi: Tata McGraw Hill; 2009. pp. 238-39.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 15 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Disopyramide. [Accessed 15 Mar. 2019] (online) Available from:
  6. Disopyramide phosphate [Product Information]. Peapack, NJ: Greenstone LLC; 2019. [Accessed 03 Apr. 2025] (online) Available from:
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User feedback

Thrice A Day
40%
Once A Day
30%
Twice A Day
25%
Alternate Day
5%
Arrhythmia
80%
Others
20%
Excellent
71%
Average
29%
No Side Effect
83%
Blurred vision
17%
With or without food
67%
With food
33%
Average
39%
Not Expensive
33%
Expensive
28%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India
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