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MBA, MBBS
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Rani 150mg Tablet

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SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Rani 150mg Tablet is used to treat and prevent peptic ulcer disease, GERD, and acidity, including conditions caused by excessive gastric acid secretion such as hypersecretory states, NSAID-related gastric injury, stress-related mucosal damage, and prevention of acid aspiration in high-risk patients.

Rani 150mg Tablet helps promote the healing of stomach and intestinal ulcers and prevents them from recurring. It is also commonly prescribed to prevent heartburn and ulcers caused by the use of painkillers. Take it exactly as prescribed by your doctor. The dose and duration depend on your condition and response to treatment, so follow your doctor’s instructions carefully.


This medicine usually provides relief from indigestion and heartburn within a few hours, and it may only be needed for short-term use when symptoms occur. However, if you are taking it to prevent ulcers or manage ongoing acid-related conditions, your doctor may advise longer use. Taking it regularly can help prevent symptoms from returning. You can also support your treatment by eating smaller, more frequent meals and avoiding spicy or fatty foods.


Most people do not experience side effects while taking this medicine. However, common ones may include headache, constipation, diarrhea, or mild drowsiness. These effects are usually temporary and improve as your body adjusts to the medicine. Consult your doctor if they persist or cause discomfort.


Before starting Rani 150mg Tablet, inform your doctor if you have liver or kidney problems, as your dose may need adjustment. Also, tell your doctor about any other medicines you are taking, since some may interact with this one. Rani 150mg Tablet is generally considered safe during pregnancy and breastfeeding when prescribed by a doctor. Avoid alcohol, as it can increase stomach acid and worsen your symptoms.


Uses of Rani Tablet

Benefits of Rani Tablet

In Management of Peptic ulcer disease

Rani 150mg Tablet helps treat and prevent peptic ulcers, including duodenal ulcers, benign gastric ulcers, and post-operative ulcers, and is used for maintenance therapy to prevent recurrence. It is also used to prevent re-bleeding in patients with a history of bleeding peptic ulcers. It lowers stomach acid levels and allows ulcerated tissue in the stomach or intestine to heal effectively, reducing irritation and pain. This supports recovery and helps prevent ulcer recurrence when taken as directed by your doctor.

In Treatment of Gastroesophageal reflux disease (Acid reflux)

Rani 150mg Tablet is used in the treatment and long-term management of gastro-oesophageal reflux disease, including cases with reflux esophagitis, to relieve symptoms and promote healing of the esophageal lining. It reduces excess acid production in the stomach, which helps prevent acid from flowing back into the food pipe. This eases heartburn, acidity, and discomfort after meals and improves overall comfort when used regularly as prescribed.

In Control Acidity

Rani 150mg Tablet helps control conditions associated with excessive stomach acid production, including acid hypersecretory states such as Zollinger–Ellison syndrome, NSAID-associated gastric and duodenal injury, and stress-related mucosal damage in seriously ill patients. It is also used in high-risk situations to reduce gastric acidity for the prevention of acid aspiration during anesthesia. It works by reducing acid levels and protecting the stomach lining, reducing irritation and helping prevent acid-related complications.

Side effects of Rani Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rani

  • Headache
  • Gastrointestinal disturbance
  • Diarrhea

How to use Rani Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rani 150mg Tablet may be taken with or without food.

How Rani Tablet works

Rani 150mg Tablet works by blocking histamine H2 receptors on the acid-producing cells of the stomach. This reduces both basal and stimulated secretion of gastric acid, lowering the volume and acidity of stomach contents. By decreasing acid production, ranitidine helps relieve acid-related symptoms and allows irritated or ulcerated areas of the stomach and esophagus to heal.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rani 150mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Rani 150mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Rani 150mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Rani 150mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Rani 150mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Rani 150mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

What if you forget to take Rani Tablet?

If you miss a dose of Rani 150mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Rani 150mg Tablet
₹0.51/Tablet
Retiva Tablet
Leeford Healthcare Ltd
₹1.01/tablet
98% costlier
Monorin 150 Tablet
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₹1.16/tablet
127% costlier
Aciloc 150 Tablet
Cadila Pharmaceuticals Ltd
₹1.56/tablet
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Rantac 150 Tablet
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₹1.54/tablet
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R-Loc 150 Tablet
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₹1.58/tablet
210% costlier

Quick tips

  • If you are also taking other medications to treat acidity (e.g., antacid), take them 2 hours before or after taking Rani 150mg Tablet.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Rani 150mg Tablet for 2 weeks as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney disease, as the dose of your medicine may need to be adjusted.
  • Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class
Heterocyclic amines
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Histamine Type-2 Receptor Antagonists (H2 Blockers)

Interaction with drugs

Taking Rani with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Ranitidine may reduce blood levels of Pazopanib. Ranitidine may reduce blood levels of Pazopanib. Avoid concomitant use. Please consult with your doctor for safer alternative of Ra... More
Ranitidine may reduce blood levels and efficacy of Dasatinib. Ranitidine may reduce blood levels and efficacy of Dasatinib. Do not consume Dasatinib with Ranitidine.
To take Cefpodoxime Proxetil, ensure a gap of at least 2 hours before taking Ranitidine. Ranitidine may reduce blood levels of Cefpodoxime Proxetil.
Talk to your doctor if you notice any unusual symptoms. Although the likelihood is low, concurrent use may cause a slow heart rate.
Talk to your doctor if you notice any unusual symptoms. Concurrent use may potentially alter the blood levels of both medications.

Patient concerns

Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often
Dr. Vijay Verma
ENT
it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

User feedback


FAQs

Is Rani 150mg Tablet effective?

Rani 150mg Tablet would be effective only if used for the right indication in the dose and the duration as advised by the doctor. In case you do not find any change in your condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.

What are the dos and don’ts while taking Rani 150mg Tablet?

Avoid taking aspirin and other painkillers used to treat arthritis, period pain, or headache. These medicines may irritate the stomach and make your condition worse. Contact your doctor who may suggest other medicines. Avoid coffee, tea, cocoa, and cola drinks because these contain ingredients that may irritate your stomach. Eat smaller, more frequent meals. Eat slowly and chew your food carefully. Try not to rush while having meals. You should stop or cut down on smoking.

Can I take alcohol with Rani 150mg Tablet?

Alcohol does not interfere with the working of Rani 150mg Tablet. However, you should avoid taking alcohol as it may further damage the stomach, delaying your recovery.

How long does it take for Rani 150mg Tablet to start working?

Rani 150mg Tablet starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.

Can I take Rani 150mg Tablet empty stomach?

Rani 150mg Tablet may be taken with or without food. It can be taken once daily before bedtime or twice daily in the morning and before bedtime, as recommended.

What are the serious side effects of Rani 150mg Tablet?

Rani 150mg Tablet may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, hoarseness, and difficulty in breathing or swallowing. Another serious symptom may be swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs. Inform your doctor in case you notice any of the mentioned symptoms.

Is Rani 150mg Tablet safe for long-term use?

There is limited data available on whether Rani 150mg Tablet can be used for the long term or not, but it is a relatively safe medicine. You should take it for the duration advised by your doctor. Do not take over-the-counter Rani 150mg Tablet for longer than 2 weeks unless advised by your doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ranitidine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Ranitidine hydrochloride [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals; 2022. [Accessed 25 Jul. 2024] (online) Available from: External Link
  4. Ranitidine [Product Monograph]. Laval, Québec: Pro Doc Ltée; 2018. [Accessed 17 Jan. 2026] (online) Available from: External Link

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