Quinine Dihydrochloride 300mg Injection
Prescription Required
Product introduction
Quinine Dihydrochloride 300mg Injection is an antiparasitic medicine, used for the treatment of malaria. It may also be used to treat and prevent nighttime leg cramps. It works by killing the malaria-causing parasite and stops the infection from spreading.
Quinine Dihydrochloride 300mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Take measures to reduce the chance of being bitten by mosquitoes like using insect repellent creams on parts of your body, not covered by clothing. Spray mosquito repellent to kill any mosquitoes that may have entered rooms despite screening. Wear light-colored and covered clothing when you are outside after sunset.
Some people may experience vomiting, deafness, headache, and dizziness as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. Please consult your doctor if these side effects do not resolve or persist for a longer duration.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. It may cause blurring of vision. Therefore, regular eye examinations are recommended while on treatment with this medicine. When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.
Quinine Dihydrochloride 300mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Take measures to reduce the chance of being bitten by mosquitoes like using insect repellent creams on parts of your body, not covered by clothing. Spray mosquito repellent to kill any mosquitoes that may have entered rooms despite screening. Wear light-colored and covered clothing when you are outside after sunset.
Some people may experience vomiting, deafness, headache, and dizziness as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. Please consult your doctor if these side effects do not resolve or persist for a longer duration.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. It may cause blurring of vision. Therefore, regular eye examinations are recommended while on treatment with this medicine. When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.
Uses of Quinine Dihydrochloride Injection
Benefits of Quinine Dihydrochloride Injection
In Malaria
Quinine Dihydrochloride 300mg Injection is an antimalarial medicine and is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes). However, this medicine should not be used to prevent malaria or to treat severe cases of malaria. This medicine is given by a doctor or nurse and should not be self-administered. Refrain from taking any other medicines or antacids along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.
Side effects of Quinine Dihydrochloride Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Quinine Dihydrochloride
- Vomiting
- Deafness
- Headache
- Dizziness
- Injection site reactions (pain, swelling, redness)
How to use Quinine Dihydrochloride Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Quinine Dihydrochloride Injection works
Quinine Dihydrochloride 300mg Injection is an antiparasitic medication which treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Quinine Dihydrochloride 300mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Quinine Dihydrochloride 300mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Quinine Dihydrochloride 300mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Quinine Dihydrochloride 300mg Injection may cause side effects which could affect your ability to drive.
Quinine Dihydrochloride 300mg Injection may affect your vision and cause vertigo (dizziness or spinning sensation) which may affect your ability to drive.
Quinine Dihydrochloride 300mg Injection may affect your vision and cause vertigo (dizziness or spinning sensation) which may affect your ability to drive.
Kidney
CAUTION
Quinine Dihydrochloride 300mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Quinine Dihydrochloride 300mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Quinine Dihydrochloride 300mg Injection should be used with caution in patients with liver disease. Dose adjustment of Quinine Dihydrochloride 300mg Injection may be needed. Please consult your doctor.
What if you forget to take Quinine Dihydrochloride Injection?
If you miss a dose of Quinine Dihydrochloride 300mg Injection, consult your doctor.
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Quick tips
- Quinine Dihydrochloride 300mg Injection helps in the treatment of malaria.
- Do not drive or do anything that requires mental focus until you know how Quinine Dihydrochloride 300mg Injection affects you.
- Have regular eye tests done while you are taking this medicine. Stop taking Quinine Dihydrochloride 300mg Injection and immediately inform your doctor if you notice any changes in your vision.
- Inform your doctor if you develop a rash or ringing in your ears.
- It can cause lowering of blood sugar level. Inform your doctor if you experience symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Fact Box
Chemical Class
Cinchona alkaloid
Habit Forming
No
Therapeutic Class
ANTI MALARIALS
Action Class
Antimalarial- others
Interaction with drugs
Taking Quinine Dihydrochloride with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Pimozide with Quinine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Haloperidol with Quinine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Amiodarone with Quinine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Escitalopram Oxalate with Quinine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Quinine.
Patient concerns
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FAQs
Who should not use Quinine Dihydrochloride 300mg Injection?
Use of Quinine Dihydrochloride 300mg Injection should be avoided in patients who are allergic to Quinine Dihydrochloride 300mg Injection or any of its components. However, if you are not aware of any allergy or if you are using Quinine Dihydrochloride 300mg Injection for the first time, consult your doctor.
What should I tell my doctor before starting treatment with Quinine Dihydrochloride 300mg Injection?
Before starting treatment with Quinine Dihydrochloride 300mg Injection, inform your doctor if you have any other health conditions like kidney or heart-related problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Also, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant or breastfeeding.
Is Quinine Dihydrochloride 300mg Injection safe?
Quinine Dihydrochloride 300mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
How long does it take for malaria symptoms to show?
Symptoms of malaria can develop as quickly as 7 days after you are being bitten by an infected mosquito. Typically, the time between being infected and the appearance of symptoms (incubation period) is 7 to 18 days. However, in some cases it can take up to one year for the symptoms to develop. Initial symptoms of malaria are flu-like which include feeling hot and shivery, muscle pains, vomiting, headaches and diarrhea.
How can you prevent yourself from getting malaria?
Malaria can be avoided by taking the right approach towards prevention. Avoid mosquito bites by covering your arms and legs, using mosquito net and insect repellent. Check with your doctor whether you need to take malaria prevention tablets. If you do, make sure you take the right antimalarial tablets at the right dose, and finish the proper course of treatment. Seek immediate medical advice from the doctor if you have malaria symptoms.
How is Quinine Dihydrochloride 300mg Injection administered?
Quinine Dihydrochloride 300mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Quinine Dihydrochloride 300mg Injection.
Can I take Quinine Dihydrochloride 300mg Injection if I have kidney disease?
Quinine Dihydrochloride 300mg Injection should be used with caution in patients having an impaired kidney function. Do not self medicate and avoid its use. If the impairment is very severe then the use of this medicine should be avoided. Therefore, inform your doctor before taking Quinine Dihydrochloride 300mg Injection.
Can I take Quinine Dihydrochloride 300mg Injection when I am pregnant?
No, the use of Quinine Dihydrochloride 300mg Injection is not recommended during pregnancy as it may harm your unborn baby. Seek proper advice from your doctor on using this medicine, if you are pregnant.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Vinetz JM, Clain J, Bounkeua V, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1405-407.
- Rosenthal PJ. Antiprotozoal Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 905-906.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1188.
- WHO Model Prescribing Information: Drugs Used in Parasitic Diseases. 1995. PP 38-41. [Accessed 08 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Merck Ltd
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India
Country of origin: India
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