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Cinkona 300mg Injection

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Ipca Laboratories Ltd

Composition for Cinkona 300mg Injection

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Primary uses of Cinkona 300mg Injection

Malaria, Cerebral malaria
MRP
9
1 ml in 1 vial
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Medicine Overview of Cinkona Injection

uses

Uses of Cinkona Injection

Cinkona 300mg Injection is used in the treatment of malaria and Cerebral malaria.
uses

Cinkona Injection side effects

Common

Nausea, Abdominal pain, Blurred vision, Changes in color vision, Dizziness, Face redness, Headache, Altered heart rate, Increased sweating, Ringing in ear, Vertigo, Vomiting.

uses

How to use Cinkona Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cinkona Injection works

Cinkona 300mg Injection is a weak base that reaches high concentration within the malarial parasite and causes accumulation of toxic heme pigment, which kills it.

In Depth Information on Cinkona Injection

Expert advice for Cinkona Injection

  • Take this medication with meals to minimize chances of stomach upset.
  • Tell your doctor if you have any heart problems related to irregular rhythm of heartbeats or any liver or kidney disorder.
  • Seek immediate medical attention if you experience unexplained bleeding or bruising as quinine may decrease platelet count in blood (thrombocytopenia).
  • You should regularly check the blood glucose levels during the treatment with quinine.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not take if allergic to quinine or any of its ingredients or mefloquine or quinidine.
  • Avoid if Patients have prolonged QT interval (disordered electrical activity of heart leading to heart disorders).
  • Avoid if Patients is suffering from glucose-6-phosphate dehydrogenase deficiency (a hereditary disorder affecting red blood cells).
  • Do not take if suffering from myasthenia gravis (a rare disorder characterized by severe muscle weakness).
  • Avoid if Patients has optic neuritis (inflammation of the eye nerve causing visual disorders).
  • Do not take if Patients have history of blackwater fever (a complication of malaria), thrombotic thrombocytopenic purpura (a rare blood disorder) or thrombocytopenia (abnormally low number of platelets in blood).
  • Avoid if Patients is suffering from tinnitus (ringing in ears) or hematuria (blood in the urine).
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Cinkona Injection related warnings
Special precautions for Cinkona Injection
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Cinkona 300mg Injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Cinkona 300mg Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Cinkona 300mg Injection may affect your vision and cause vertigo (dizziness or spinning sensation) which may affect your ability to drive.
Kidney
CAUTION
Cinkona 300mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Cinkona 300mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Cinkona 300mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cinkona 300mg Injection may be needed. Please consult your doctor.

Patient Concerns

Frequently asked questions about Cinkona Injection

Frequently asked questions about Quinine

Yes. Cinkona is used in certain cases to prevent and treat night leg cramps which regularly disrupt sleep
No. Cinkona is not indicated for use in neurological conditions like restless leg syndrome. It is used in certain cases to prevent and treat night leg cramps
Q. Is quinine an alkaloid/ a stimulant/ a diuretic?
Quinine is an alkaloid obtained from bark of the cinchona tree. It is not a stimulant (i.e. does not stimulate the brain or any mental functions) or a diuretic (does not increase urine output)
Q. Can you take quinine with warfarin?
Taking warfarin with quinine may increase risk of unexplained bleeding or bruising as quinine may decrease platelet count in blood (thrombocytopenia). Please inform your doctor about all medications you are taking currently before starting quinine treatment
No. Cinkona does not prevent malaria. It is used for the treatment of malaria (caused by parasite Plasmodium falciparum) which is resistant to multiple drugs including chloroquine.
Severely interacts with other drugs like
Taking Cinkona with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Cinkona with Digoxin
SERIOUS
Medicines with composition Digoxin: Digon, Cardioxin, Lanoxin, Sangoxin, Digitran, Digoxin, Celoxin, Dixin
Cinkona with Lafutidine
MINOR
Medicines with composition Lafutidine: Lafter, Lafudac, Lafty, Lafukem, Lafaxid, Laciloc, Lafumac, Swiftin, Laftid, Histolaf, Lafjoy, Lafadin, Futaden
Cinkona with Cimetidine
MINOR
Medicines with composition Cimetidine: Acitak, Cimetiget, Tymidin, Ulciban
Cinkona with Roxatidine
MINOR
Medicines with composition Roxatidine: Rotane, Zorpex
Cinkona with Nizatidine
MINOR
Medicines with composition Nizatidine: Axid
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