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Propeg 200mg Capsule is a medicine used in the treatment of treat breast cancer, endometriosis, and endometrial cancer. The medicine helps to slow down the growth and multiplication of cancer cells.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)
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Propeg 200mg Capsule image
Propeg 200mg Capsule image

Product introduction

Propeg 200mg Capsule should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.

Common side effects of this medicine include headache, dizziness, weakness, weight gain, irregular menstrual cycle, and abdominal pain. Most of these are temporary and go away as soon as the body adjusts to the treatment. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. You should also inform the doctor immediately if it causes severe headaches, swelling in one leg, pain on breathing, or changes in vision or hearing.

Before taking this medicine you should let your doctor know if you ever had any problem like unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems. You should also inform the doctor about all other medicines that you are taking. Pregnant and breastfeeding women should not take this medicine.

Benefits of Propeg Capsule

Treatment of Abnormal uterine bleeding
Propeg 200mg Capsule is a synthetic progestin that replicates the effect of a natural female hormone called progesterone. It slows the growth of the lining of the womb before menstruation, which reduces the bleeding during menstruation. If heavy periods become such a problem that they interfere with your everyday life, then try taking things a little easier on those days. Some women find that relaxation techniques or yoga help them feel more relaxed and reduce stress. Getting a lot of exercise can also help.
Treatment of Endometriosis
Propeg 200mg Capsule contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. You should use the medicine as prescribed for it to be effective. Avoid any stress and follow your doctor’s instructions carefully. Improving weight and nutrition may be recommended in females with eating disorders or malnutrition to get the maximum benefit from Propeg 200mg Capsule.
Endometrial cancer
Propeg 200mg Capsule is a synthetic hormone which replicates the effect of a natural female hormone called progesterone. It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc. This medicine interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer. It may also have a direct effect on the cancer to stop its growth.

Side effects of Propeg Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Propeg
  • Headache
  • Abdominal pain
  • Weakness
  • Dizziness
  • Irregular menstrual cycle
  • Nervousness
  • Weight gain

How to use Propeg Capsule

Take this medicine in the dose and duration as advised by your doctor. Propeg 200mg Capsule may be taken with or without food.

How Propeg Capsule works

Propeg 200mg Capsule is a hormone. It works by decreasing the levels of certain hormones required by cancer cells to grow. It may also interact with other hormones or have a direct effect on the cancer to stop it growing.

Quick tips

  • Propeg 200mg Capsule is used for the treatment of cancer in the breast, kidney (in men and women) and in the lining of the womb (endometrial cancer).
  • Stop taking Propeg 200mg Capsule and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, pain on breathing, sudden changes in your vision or hearing, or yellowing of your skin or whites of your eyes.
     
  • Use a non-hormonal method of contraception such as condoms to prevent pregnancy while you are taking this medication.
  • Do not take Propeg 200mg Capsule if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Propeg 200mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Propeg 200mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Propeg 200mg Capsule does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Propeg 200mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Propeg 200mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Propeg with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Letrozole (Oral Route)

Do not consume Letrozole with Medroxyprogesterone acetate if you have or had breast cancer. If essential, consult your doctor.
Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Phenobarbitone (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Phenobarbitone may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Phenobarbitone (Injection Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Phenobarbitone may reduce the efficacy of Medroxyprogesterone acetate.
Severe

Lorlatinib (Oral Route)

Do not consume Lorlatinib with Medroxyprogesterone acetate. Lorlatinib may reduce blood levels of Medroxyprogesterone acetate.

Frequently asked questions

Propeg 200mg Capsule contains Medroxyprogesterone, which is similar to the natural progesterone produced by your body. It is used in the treatment of breast cancer and endometrial cancer. It is also helpful in the treatment of cancer of the kidneys in men and women. Propeg 200mg Capsule helps to slow down the growth and multiplication of cancer cells, thereby helping in recovery.
You should take Propeg 200mg Capsule strictly as per the advice of your doctor. The dosage and duration of the Propeg 200mg Capsule will vary on the medical condition you are being treated for. Your doctor may monitor you closely during your treatment with Propeg 200mg Capsule.
If you miss a dose, you should take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue the usual dosing schedule.
The common side effects of Propeg 200mg Capsule include vomiting, constipation, feeling sick, change in appetite, mood swings, weight fluctuation, and unusual vaginal bleeding or spotting. If any of the side effects persist, you should check with your doctor.
Depo-Provera is an injection form of Medroxyprogesterone which is used as a contraceptive injection for women. Whereas, Propeg 200mg Capsule is an oral form of Medroxyprogesterone and is not used as a contraceptive. Instead, it is used in treating breast cancer, endometrial cancer and cancer of the kidneys.
Propeg 200mg Capsule is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Progestins (First generation)

Related lab tests

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Unimarck Healthcare Ltd
Address: 128, HPSIDC . Inds. Area , baddi -173205(H.P)

Vendor Details

Country of origin: India
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