Promez 20 mg Capsule


Overview

Uses of Promez Capsule
Promez 20 mg Capsule is used in the treatment of acidity, peptic ulcer disease and gastroesophageal reflux disease (acid reflux).
Promez Capsule side effects
Common
  • Headache
  • Stomach pain
  • Nausea
  • Flatulence
  • Diarrhoea
How to use Promez Capsule
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Promez 20 mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Promez Capsule works
Promez 20 mg Capsule is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
Promez Capsule related warnings
Alcohol
CAUTION
Pregnancy
WEIGH RISKS VS BENEFITS
Promez 20 mg Capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Promez 20 mg Capsule is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Promez 20 mg Capsule may cause dizziness and visual disturbances. This may affect your driving ability.
Kidney
SAFE
Promez 20 mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Promez 20 mg Capsule is recommended.
Liver
Promez 20 mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Promez 20 mg Capsule may be needed. Please consult your doctor.
A lower dose may be advised in patients with liver disease and who have to take this medicine for a long time.
What if you miss a dose of Promez Capsule?
If you miss a dose of Promez 20 mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Promez 20 mg Capsule
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Expert Advice

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  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • You have been prescribed Promez 20 mg Capsule to reduce stomach acid and heal stomach ulcers.
  • Take it one hour before the meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.

Interaction with Drugs

Taking Promez with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Mgmax
SERIOUS
Brand(s): Risure
SERIOUS
Brand(s): Panik
SERIOUS
Brand(s): Dizapam
SERIOUS
Brand(s): Eurolam, Tenzo
SERIOUS
Brand(s): Psycopan
SERIOUS
Brand(s): Clopinorm
SERIOUS
Brand(s): Stoin
MODERATE
Brand(s): Methosis
MODERATE
Brand(s): Zuroxy, Roxilim, Rox Thro
MINOR

Patient Concerns

Questions Related to Promez

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Now I am taking esomeprazole-40mg once in the morning in empty stomach. What is the best medicine in ayurveda for acidity?What should be best medicine in stead of allopathic?
Dr. Aanchal Maheshwari
Ayurveda
there are a lotbof medicines to cure acidity in Ayurveda. syrup smllapitta mishran 10 ml thrice before meal, and powder anago 1 spoon befre meal twice. Anago powder is my self prepared medicine and is very effective. follow a healthy lifestyle, avoid junk spicy oily food
I have acidity &lots of gases problemsI am waiting. Thanku
Dr. Pushkar Mani
Diabetes Specialist
take RABEKIND DSR twice daily 1 hour before breakfast and 1 hour before dinner for 4 weeksTab ZINCOVIT once daily after breakfast for 4 weeksSyrup ULGEL 10ml twice daily with meals for 2 weeks
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Do you have any questions related to Promez 20 mg Capsule?

FAQs

Q. Can I take Promez with domperidone?
Promez can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Rabeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Q. What are the various conditions in which the use of Promez is contraindicated?
Use of Promez is contraindicated if you are allergic to this medicine or any other medicine belonging to the same class of drugs. Also, do not take Promez if you are already taking a medicine containing nelfinavir (used for the treatment of HIV infection).
Q. What if I miss my dose of Promez?
If you miss a dose of Promez, take it as soon as you remember and the next dose as scheduled. However, if it is almost the time for your next dose, skip the missed dose and take your next dose and then follow the regular schedule. Do not take double the dose.
Q. Can I take Promez along with oral contraceptive pills (birth control pills)?
Promez can be safely taken with oral contraceptive pills (birth control). They do not affect each other's action and no harmful effects have been seen when they are used together.
Q. What is Promez?
Promez belongs to the group of medicines known as proton pump inhibitors (PPIs). This drug decreases the acid production in your stomach and is indicated for the treatment of conditions caused by excess acid secretion in the stomach.
Q. Can Promez cause subacute cutaneous lupus erythematosus?
Promez has been reported to cause subacute cutaneous lupus erythematosus in many studies. Common signs and symptoms of this disease include painful joints, tiredness, weakness, rash, fever, anemia, mouth ulcers, hair loss, and many others and these may get aggravated again and again. Talk to your doctor if you experience these side effects as you may need to discontinue this medicine.
Q. Can I take Promez with ondansetron?
Ondansetron is an anti-emetic medicine which helps in relieving nausea (feeling sick) or vomiting. No harmful effects have been seen when Promez is used with ondansetron. So, these two medicines can be taken together.
Q. Can Promez cause lactose intolerance?
Lactose intolerance has been reported with the use of Promez in some patients. Many Promez preparations contain lactose as an ingredient. This is a digestive problem in which the patient cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.
Q. Can I take Promez with Vitamin E?
Promez can be taken with vitamin E. The combinations seems to have a beneficial effect in terms of better maintenance of moderate to severe esophagitis. However, there are not many studies or reports on this subject. Talk to your doctor for more information on this.
Q. Can I take Promez with levosulpiride?
Promez can be safely taken with levosulpiride as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Levosulpiride works by increasing the gut motility and Promez decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
Q. Does Promez use increase the risk of clostridium difficile infection?
Use of proton pump inhibitors (PPIs) like Promez may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD) as reported in few studies and informed by the US FDA as well. A possibility of CDAD can be there in patients taking PPIs and developed diarrhea that does not improve.
Q. Can Promez be used in cancer patients?
Promez can be taken by cancer patients as prescribed by a doctor. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with Promez.
Q. For how long can Promez be taken?
Take Promez for as long as advised by your doctor. The duration of taking Promez would vary depending on your condition. Do not stop taking this medicine without talking to your doctor.
Q. Can Promez cause calcium deficiency and osteoporosis?
Promez can cause osteoporosis (thinning of bones) as it decreases the calcium absorption leading to calcium deficiency. This leads to an increased risk of bone fractures on long-term use, like hip, wrist or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Take enough calcium and vitamin D to reduce the risk.
Q. What are the rare side effects of Promez?
Rare side effects seen with the use of Promez includes a decrease in white cells or platelets, allergic reactions, problems like blurred vision, wheezing, shortness of breath (bronchospasm), dry mouth, thrush, liver problems like jaundice, hair loss (alopecia), skin rash on exposure to sunshine, joint pains (arthralgia) or muscle pains (myalgia), severe kidney problems (interstitial nephritis), increased sweating and inflammation of the gut causing diarrhoea.
Q. How does Promez work?
Proton (acid) pumps are found on the stomach mucosa and they are responsible for secreting acid in the stomach. Promez works by blocking this gastric acid pump and this unique mechanism of action helps in decreasing the acid secretion in the stomach.
Q. Does Promez cause hepatitis B and can a patient of hepatitis take Promez?
Promez can rarely cause hepatitis with or without jaundice and very rarely it can lead to hepatic failure and encephalopathy in patients with the underlying liver disease. Promez does not cause hepatitis B or any other viral hepatitis. However, there are studies showing an increased occurrence of hepatic encephalopathy in hepatitis B patients using PPIs. These medicines should be used with caution in patients with the underlying liver disease.
Q. Does Promez increase chromogranin levels?
Use of proton pump inhibitors like Promez has been seen to be associated with an increase in chromogranin levels. This increase in chromogranin levels can be due to the effect of these drugs on enterochromaffin cells and this could also falsely increase the levels in patients with neuroendocrine tumours.
Q. Does Promez cause dementia?
Use of proton pump inhibitors like Promez has been recently linked with the development of dementia in elderly patients. As this risk of developing dementia is not confirmed, talk to your doctor for more information on this effect.
Q. Does Promez cause vitamin deficiencies?
Promez may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while Promez causes a decrease the gastric acid secretion. You may need to take vitamin B12 supplements from outside. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.
Q. Does Promez have an expiry date?
Yes, Promez does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Promez after the expiry date.
Q. What is the role of Promez before endoscopy in patients with gastrointestinal bleeding?
Promez before endoscopy in patients with gastrointestinal bleeding reduces the need for endoscopic therapy, the rate of post-endoscopy bleeding, and shortens hospital stays. Hence Promez is given before endoscopy in patients with gastrointestinal bleeding.
Q. Are there any withdrawal symptoms associated with the use of Promez?
There are no withdrawal symptoms seen when patients stop using Promez as it has no habit forming tendencies.
Q. Can Promez cause magnesium deficiency?
Promez can cause magnesium deficiency in the blood. Low magnesium levels is a rare side effect seen in patients treated with Promez for at least three months and in most cases after a year of therapy. The patient may have symptoms like tetany, arrhythmias, and seizures and may need to stop this medicine and take magnesium from outside. Magnesium levels should be tested at regular intervals in the patients taking Promez for a long duration.
Q. Is Promez a controlled substance?
Promez is not a controlled substance. It is available when prescribed by a doctor.
Q. Can Promez be used in cardiac patients?
Patients with cardiac disease can take Promez. However, Promez can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with an underlying cardiac disease. Patients taking Promez and digoxin may need to be monitored for digoxin toxicity. Promez decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored closely by a doctor.
Q. Can the use of Promez cause iron deficiency?
Use of Promez can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Promez.
Q. Is Promez a narcotic substance?
Promez is a not a narcotic substance and has not been reported to have any abuse potential. Promez does not get you high and does not cause any addiction as no withdrawal symptoms have been reported when you stop taking this drug.
Q. Is Promez available without a prescription as an over the counter product?
Promez is a prescription medicine and you can buy this drug by providing a doctor's prescription. Promez is not available as an over the counter (OTC) product.
Q. How is Promez metabolised in the body?
Promez is metabolized in the liver by the cytochrome P450 enzymes mainly CYP2C19. There could be an increase in the level of Promez in patients with underlying liver disease because of a decrease in its metabolism. However, the amount of drug does not increase if given once a day.
Q. Can Promez be used in stroke patients?
Promez can be used in stroke patients. There are studies suggesting that proton-pump inhibitors (PPIs) as a class are not associated with an increased short-term risk of recurrent stroke or death among older adults treated with clopidogrel after stroke.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.
Manufacturer/Marketer Address
3/A Gold Coin Complex, Joghpur Char Rasta, Ahmedabad - 380001
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