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Proapaci 60 Tablet

Apalutamide (60mg)

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Proapaci 60 Tablet is a medication used in the treatment of prostate cancer. It works by blocking the effects of testosterone on prostate cancer cells, which help slow down the growth and spread of prostate cancer. It is often used in combination with other therapies to treat prostate cancer.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)

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General Information

Contains

Apalutamide (60mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Proapaci 60 Tablet may be taken with or without food. However, always take it in the dose and duration prescribed by your doctor. Also, continue taking this medicine for as long as your doctor prescribes it, as missing a dose or stopping the treatment prematurely can reduce its effectiveness and may impact overall treatment outcomes.

Some common side effects of this medicine include fatigue, skin rash, hypertension, hot flush, arthralgia, diarrhea, falls, and weight loss. These side effects mostly occur at the initial stage of the treatment and usually disappear within a few days with continued treatment. However, let your doctor know if any of these side effects get worse or bother you. The doctor may also monitor you regularly to check the effectiveness of the medicine.

Proapaci 60 Tablet is not suitable for everyone. To make sure it is safe for you, let your doctor know if you have a known history of allergic reactions to any of the ingredients of this medicine or have any other pre-existing medical conditions. Also, inform the doctor if you are taking, have recently taken, or might take any other medicines. This medicine is also contraindicated in pregnant or breastfeeding women, as it can cause harm to the developing fetus or nursing baby.

Uses of Proapaci Tablet

Treatment of Prostate cancer

Benefits of Proapaci Tablet

Treatment of Prostate cancer
Proapaci 60 Tablet blocks the effects of testosterone on cancer cells, which in turn slows down the growth and spread of the cancer. It helps to control the cancer progression and improves the patient's overall condition and quality of life.

Side effects of Proapaci Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Proapaci

Decreased appetite
Increased risk of bone fractures
Joint pain
Diarrhea
Fatigue
Skin rash
High blood pressure
Flushing (sense of warmth in the face, ears, neck and trunk)
Fall
Weight loss

How to use Proapaci Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Proapaci 60 Tablet may be taken with or without food.

How Proapaci Tablet works

Prostate cancer cells depend on androgens to grow and survive. Even in cases where the cancer becomes resistant to standard hormonal therapies (castration-resistant), androgen receptors in the cancer cells continue to be active and promote cancer growth. Proapaci 60 Tablet targets these androgen receptors, blocks their activation, and prevents them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.

All substitutes for Proapaci 60 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

If you have ever experienced a seizure, you must inform your doctor.
If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
Inform your doctor if you have a history of cardiovascular problems.
Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
Attend all follow-up visits with your doctor as scheduled.
If you have ever experienced a seizure, you must inform your doctor!
If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
Inform your doctor if you have a history of cardiovascular problems.
Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
Attend all follow-up visits with your doctor as scheduled.
The doctor may monitor your liver function while you are on Proapaci 60 Tablet treatment, as it can affect liver enzymes.
You have been prescribed Proapaci 60 Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
Do not drive or do anything requiring concentration unless you know how Proapaci 60 Tablet affects you.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Proapaci 60 Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Proapaci 60 Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Proapaci 60 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Proapaci 60 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Proapaci 60 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Proapaci 60 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Proapaci 60 Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Proapaci with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Nevirapine (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Nevirapine.

Severe

Mifepristone (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Mifepristone.

Severe

Fenfluramine (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may reduce blood levels of Fenfluramine.

Severe

Aprepitant (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Aprepitant.

Severe

Isoflurane (Inhalation Route)

Concurrent use should be avoided. Please consult with your doctor.

Frequently asked questions

What is Proapaci 60 Tablet used for?

Proapaci 60 Tablet is used to treat certain types of prostate cancer that are still growing even when testosterone levels are low (called castration-resistant prostate cancer), or that have spread to other parts of the body but are still sensitive to testosterone (called metastatic castration-sensitive prostate cancer). It helps slow down cancer growth and lowers the risk of it spreading further.

Can Proapaci 60 Tablet be used alone for prostate cancer treatment?

Your doctor may prescribe Proapaci 60 Tablet along with another treatment that lowers testosterone, such as surgery to remove the testicles, or medicines that block testosterone production. Testosterone fuels prostate cancer growth, so this product works best when testosterone levels are kept low.

Who should not take Proapaci 60 Tablet?

Individuals should not take Proapaci 60 Tablet if they are allergic to it or any of its ingredients. People with a history of severe allergic reactions, seizures, or certain heart problems should inform their doctor before starting the treatment. This product is for men only and should not be used by women or children.

What are the serious side effects of Proapaci 60 Tablet I should watch out for?

Some serious side effects of Proapaci 60 Tablet may include seizures, fainting, falls, fractures, severe skin rash, or allergic reactions such as swelling and trouble breathing. If you experience any of these symptoms, get medical help right away.

Can Proapaci 60 Tablet cause skin reactions or rashes?

Yes, some people may develop skin rashes or allergic reactions while taking Proapaci 60 Tablet. Severe skin rashes may include redness, blisters, or peeling. Contact your doctor immediately if you notice these symptoms.

Does Proapaci 60 Tablet affect bone strength or increase fracture risk?

Yes, Proapaci 60 Tablet can make bones weaker, especially when used with testosterone-lowering treatments. This may increase the risk of falls or bone fractures. Your doctor may recommend supplements or lifestyle changes to protect your bone health.

Can women or children take Proapaci 60 Tablet?

No, Proapaci 60 Tablet is meant for adult men only. It should not be used by women or children. Women who are pregnant or may become pregnant should not handle crushed or broken product, as it may harm the unborn baby.

How does Proapaci 60 Tablet help improve survival in prostate cancer?

Proapaci 60 Tablet helps by blocking signals that drive prostate cancer cells to grow and spread. Clinical studies indicate that it may delay cancer progression and support survival in men with advanced prostate cancer when used as prescribed along with hormone therapy.

What regular monitoring is needed during Proapaci 60 Tablet?

Your doctor will monitor your blood pressure, liver function, thyroid levels, and bone health during Proapaci 60 Tablet treatment. Regular medical visits help ensure that the product is working effectively and that any side effects are managed early.

Fact Box

Chemical Class

Phenylimidazolidines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Androgen Receptor Antagonists

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Proapaci 60 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Proapaci 60 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Proapaci Tablet

Benefits of Proapaci Tablet

Side effects of Proapaci Tablet

How to use Proapaci Tablet

How Proapaci Tablet works

All substitutes for Proapaci 60 Tablet

Apatide 60mg Tablet

Apatide 60mg Tablet

Pryor Tablet

Aplet 60mg Tablet

Apnat 60mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Nevirapine (Oral Route)

Mifepristone (Oral Route)

Fenfluramine (Oral Route)

Aprepitant (Oral Route)

Isoflurane (Inhalation Route)

Frequently asked questions

What is Proapaci 60 Tablet used for?

Can Proapaci 60 Tablet be used alone for prostate cancer treatment?

Who should not take Proapaci 60 Tablet?

What are the serious side effects of Proapaci 60 Tablet I should watch out for?

Can Proapaci 60 Tablet cause skin reactions or rashes?

Does Proapaci 60 Tablet affect bone strength or increase fracture risk?

Can women or children take Proapaci 60 Tablet?

How does Proapaci 60 Tablet help improve survival in prostate cancer?

What regular monitoring is needed during Proapaci 60 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests