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Polymycetin Injection

Chloramphenicol (1gm)

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Polymycetin Injection is an antibiotic that fights bacteria. It is used to treat certain types of serious infections caused by bacteria when other antibiotics cannot be used. It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 23 Sep 2025 | 07:09 PM (IST)

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10 ml Injection

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General Information

Contains

Chloramphenicol (1gm)

Marketer

Scott Edil Pharmacia Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Polymycetin Injection is used to treat critically ill patients admitted to the hospital. It may be effective even when bacteria have developed resistance to other antibiotics. This medicine is given by drip or by direct injection into a vein, under the supervision of a doctor or nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you are prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like nausea, vomiting, diarrhea, taste change, or local redness and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you have liver or kidney problems or if you are allergic to any antibiotic. While using it, your doctor may advise some blood tests to monitor your blood cell counts. Pregnant and breastfeeding mothers should consult their doctor before using it.

Uses of Polymycetin Injection

Treatment of Severe bacterial infections

Benefits of Polymycetin Injection

Treatment of Severe bacterial infections
Polymycetin Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of the lungs (pneumonia) and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Polymycetin Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Polymycetin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Polymycetin

Vomiting
Nausea
Diarrhea
Taste change
Injection site reactions (pain, swelling, redness)

How to use Polymycetin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Polymycetin Injection works

Polymycetin Injection is an antibiotic which stops the growth of bacteria. It does so by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This does not directly kill the bacteria, but prevents them from increasing in numbers, and eventually clears up the infection.

All substitutes for Polymycetin Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor has prescribed Polymycetin Injection to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
The injection may be given into a muscle (intramuscularly) or into a vein (intravenously).
Your doctor may get blood tests done to check your blood cells before starting treatment and regularly thereafter.
Do not use Polymycetin Injection if you are pregnant, planning to conceive, or breastfeeding.
Inform your doctor if you have liver or kidney disease.
Your doctor has prescribed Polymycetin Injection to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
This can be taken either with or without food.
Your doctor may get blood tests done to check your blood cells before starting treatment and regularly thereafter.
Do not use Polymycetin Injection if you are pregnant, planning to conceive, or breastfeeding.
Inform your doctor if you have liver or kidney disease.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Polymycetin Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Polymycetin Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Polymycetin Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Polymycetin Injection may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Kidney

SAFE IF PRESCRIBED

Polymycetin Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Polymycetin Injection may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Polymycetin Injection in patients with liver disease. Please consult your doctor.

Interaction with drugs

Taking Polymycetin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Chloramphenicol. Please consult your doctor. Chloramphenicol may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Chloramphenicol may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Chloramphenicol may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Gliclazide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may monitor your diabetic control closely. Chloramphenicol may decrease the metabolism of Gliclazide.

Moderate

Glibenclamide (Oral Route)

Moderate

Glimepiride (Oral Route)

Frequently asked questions

How long does Polymycetin Injection takes to work?

Usually, Polymycetin Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

What if I don't get better after using Polymycetin Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Polymycetin Injection when my symptoms are relieved?

No, do not stop taking Polymycetin Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Fact Box

Chemical Class

Amphenicols

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Bacterial Protein Synthesis Inhibitors- Chloramphenicol

Related lab tests

Complete Blood Count

References

MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1526-29.
Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 802-803.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 244-25.
Chloramphenicol. Bristol, Tennessee: Monarch Pharmaceuticals; 2004. [Accessed 29 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Scott Edil Pharmacia Ltd
Address: Plot NO. 28/6, Industrial Area,Phase 2, Chandigarh (India)

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Polymycetin Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Polymycetin Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Polymycetin Injection

Benefits of Polymycetin Injection

Side effects of Polymycetin Injection

How to use Polymycetin Injection

How Polymycetin Injection works

All substitutes for Polymycetin Injection

Kemicetine 1gm Injection

Fencol 1gm Injection

Tromycetin 1gm Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Gliclazide (Oral Route)

Glibenclamide (Oral Route)

Glimepiride (Oral Route)

Frequently asked questions

How long does Polymycetin Injection takes to work?

What if I don't get better after using Polymycetin Injection?

Can I stop taking Polymycetin Injection when my symptoms are relieved?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests