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Poly-MxB Injection

Polymyxin B (500000IU)

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Poly-MxB Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It works by killing and stopping the growth of bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Apr 2026 | 01:19 PM (IST)

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5 ml Injection

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General Information

Contains

Polymyxin B (500000IU)

Marketer

Bharat Serums & Vaccines Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Poly-MxB Injection is given under the supervision of a healthcare professional. You should get the injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like anaphylactic reaction, kidney damage, neurotoxicity, fever, or pain, redness, and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.

Before starting treatment with this medicine, you should tell your doctor if you are allergic to any antibiotic or have any liver or kidney problems. Pregnant women should consult their doctor before using it. Your doctor may get regular blood tests done to monitor kidney function.

Uses of Poly Mxb Injection

Treatment of Severe bacterial infections

Benefits of Poly Mxb Injection

Treatment of Severe bacterial infections
Poly-MxB Injection is an antibiotic that works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections. This medicine is usually given as an injection by a doctor or nurse and should not be self-administered at home.

This medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Poly Mxb Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Poly Mxb

Anaphylactic reaction
Fever
Kidney damage
Neurotoxicity
Injection site reactions (pain, swelling, redness)

How to use Poly Mxb Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Poly Mxb Injection works

Poly-MxB Injection is an antibiotic. It kills bacteria by destroying the bacterial cell membrane.

All substitutes for Poly-MxB Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Poly-MxB Injection treats serious bacterial infections that have not responded to treatment with other antibiotics.
It is given by injection or drip (infusion) into a vein usually over 30-60 minutes.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Inform your doctor if it doesn't stop or if you find blood in your stools.
Your doctor may get regular blood tests done to monitor the level of the medicine in your blood.
Poly-MxB Injection treats serious bacterial infections that have not responded to treatment with other antibiotics.
It is given by injection or drip (infusion) into a vein usually over 30-60 minutes.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Your doctor may get regular blood tests done to monitor the level of the medicine in your blood.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Poly-MxB Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Poly-MxB Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Poly-MxB Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Poly-MxB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Poly-MxB Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Poly-MxB Injection in patients with liver disease.

Interaction with drugs

Taking Poly Mxb with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Vancomycin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.

Severe

Vancomycin (Oral Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.

Moderate

Capreomycin (Injection Route)

If concurrent use is essential, your doctor may monitor your blood pressure frequently.

Moderate

Atracurium (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required. Polymyxin B may increase the effect of Atracurium.

Frequently asked questions

What is Poly-MxB Injection? What is it used for?

Poly-MxB Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, soft tissues, heart and blood. It is commonly used to treat critically ill patients who are hospitalized.

How is Poly-MxB Injection administered?

Poly-MxB Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Poly-MxB Injection.

Is Poly-MxB Injection safe?

Poly-MxB Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What are the side effects of Poly-MxB Injection?

Some common side effects associated with Poly-MxB Injection include reduced urination, breathing problems, numbness, vertigo, blurred vision, facial redness, slurred speech and pain. However, these side effects are usually not bothersome and resolve in some time. If they persist for a longer duration or worry you, consult your doctor.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

OPHTHAL OTOLOGICALS

Action Class

Cell membrane active agent

Related lab tests

Complete Blood Count

References

MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1538-39.
Chambers HF, Deck DH. Miscellaneous Antimicrobial Agents; Disingectants, Antiseptics, & Sterilants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 878.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1133.
Polymyxin B. Bedford, Ohio: Ben Venue Laboratories, Inc.; 2011. [Accessed 28 Mar. 2019] (online) Available from:

User feedback

What are you using Poly Mxb Injection for?

Bacterial infections

60%

Others

20%

Severe bacterial infections

20%

How much was the improvement?

Excellent

50%

Average

50%

What were the side-effects while using Poly-MxB Injection?

Eye irritation

100%

How do you take Poly Mxb Injection?

Empty stomach

100%

Please rate Poly-MxB Injection on price

Not Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Poly-MxB Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Poly-MxB Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Poly Mxb Injection

Benefits of Poly Mxb Injection

Side effects of Poly Mxb Injection

How to use Poly Mxb Injection

How Poly Mxb Injection works

All substitutes for Poly-MxB Injection

Paxyb Injection

Polytuff 500000IU Injection

Poly-B Injection

Unipol B 500000IU Injection

Polyfic Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vancomycin (Injection Route)

Vancomycin (Oral Route)

Capreomycin (Injection Route)

Atracurium (Injection Route)

Frequently asked questions

What is Poly-MxB Injection? What is it used for?

How is Poly-MxB Injection administered?

Is Poly-MxB Injection safe?

What are the side effects of Poly-MxB Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

User feedback

What are you using Poly Mxb Injection for?

How much was the improvement?

What were the side-effects while using Poly-MxB Injection?

How do you take Poly Mxb Injection?

Please rate Poly-MxB Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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