Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
29 Nov 2023 | 07:00 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Pisi 20mg Tablet

Prescription Required

Product introduction

Pisi 20mg Tablet is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.

Pisi 20mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Pisi Tablet

Benefits of Pisi Tablet

In Pain relief

Pisi 20mg Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Pisi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pisi

  • Vomiting
  • Stomach pain
  • Nausea
  • Headache
  • Dizziness

How to use Pisi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pisi 20mg Tablet is to be taken with food.

How Pisi Tablet works

Pisi 20mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pisi 20mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Pisi 20mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pisi 20mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Pisi 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pisi 20mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Pisi 20mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Pisi 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pisi 20mg Tablet may be needed. Please consult your doctor.

What if you forget to take Pisi Tablet?

If you miss a dose of Pisi 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pisi 20mg Tablet
₹5.7/Tablet
₹6.65/tablet
17% costlier
₹11.4/tablet
100% costlier
Rowpax 20mg Tablet
Rowlinges Life Science
₹8.55/tablet
50% costlier
Odpar 20mg Tablet
Galaxy Biotech
₹10.4/tablet
82% costlier
Xicom 20mg Tablet
Medstry Biotech Pvt Ltd
₹8.36/tablet
47% costlier

Quick tips

  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Pisi 20mg Tablet helps relieve pain and swelling of various joints and muscles.
  • Take it with food to avoid stomach upset.
  • Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness. 

Fact Box

Chemical Class
Enolic acid Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)

Interaction with drugs

Taking Pisi with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Neil, Esulide
Life-threatening
Brand(s): Oxy Triactin, Sioril
Life-threatening
Brand(s): Pyregin, Alpagin, Novalgin RC
Life-threatening

Patient concerns

arrow
One of my teeth is sensitive. It some times pains
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief
fever and 2 months pregnant can take combiflan
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
No take Crocin for pain relief
arrow

FAQs

Q. What is the difference between Pisi 20mg Tablet and diclofenac?

Both Pisi 20mg Tablet and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pisi 20mg Tablet.

Q. What is the difference between Pisi 20mg Tablet and naproxen?

Both Pisi 20mg Tablet and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pisi 20mg Tablet.

Q. What is the difference between Pisi 20mg Tablet and meloxicam?

Both Pisi 20mg Tablet and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pisi 20mg Tablet.

Q. What is the difference between Pisi 20mg Tablet and ketoprofen?

Both Pisi 20mg Tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pisi 20mg Tablet. Ketoprofen gel also showed excellent tolerability.

Q. What is the difference between Pisi 20mg Tablet and tramadol?

Pisi 20mg Tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Q. What is the difference between Pisi 20mg Tablet and nimesulide?

Both Pisi 20mg Tablet and nimesulide are pain killers. However, Pisi 20mg Tablet is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Q. Can Pisi 20mg Tablet be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pisi 20mg Tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pisi 20mg Tablet.

Q. Are Pisi 20mg Tablet and aspirin same?

No. Pisi 20mg Tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Q. Can Pisi 20mg Tablet be used along with dexamethasone?

No. Pisi 20mg Tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.

Q. Can Pisi 20mg Tablet be used with methocarbamol?

Yes. Methocarbamol can be used with Pisi 20mg Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.

Q. Can Pisi 20mg Tablet be used along with paracetamol?

Yes. Paracetamol can be used with Pisi 20mg Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.

Q. Is Pisi 20mg Tablet a NSAID?

Yes. Pisi 20mg Tablet is a non-steroidal anti-inflammatory drug (NSAID).

Q. Is Pisi 20mg Tablet a sulfa drug?

Pisi 20mg Tablet is a sulphur containing compound. Pisi 20mg Tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Q. Is Pisi 20mg Tablet a blood thinner?

No. Pisi 20mg Tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Q. Is Pisi 20mg Tablet a muscle relaxant?

No. Pisi 20mg Tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Q. Is Pisi 20mg Tablet a narcotic?

No. Pisi 20mg Tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Q. Can Pisi 20mg Tablet be used in hypertension?

No. Pisi 20mg Tablet is not a medication to control hypertension. It is important to note that Pisi 20mg Tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.

Q. Can Pisi 20mg Tablet be used along with Losartan?

No. Pisi 20mg Tablet should not be combined with Losartan. It is important to note that Pisi 20mg Tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.

Q. Can Pisi 20mg Tablet be used with Lisinopril?

No. Pisi 20mg Tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.

Q. Can Pisi 20mg Tablet be used with calcium channel blocker?

Yes. Pisi 20mg Tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Q. Can Pisi 20mg Tablet be used with Tizanidine?

Yes, Pisi 20mg Tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Q. Why is beta cyclodextrin added to Pisi 20mg Tablet?

Yes. Pisi 20mg Tablet can be combined with beta-cyclodextrin. Research has shown that combining Pisi 20mg Tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Q. Are there any alternatives of Pisi 20mg Tablet?

Yes. There are alternatives to Pisi 20mg Tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Q. What are the contraindications for Pisi 20mg Tablet?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Q. Can Pisi 20mg Tablet be used in the treatment of allergy?

No. Pisi 20mg Tablet is not a drug to treat allergy. It is a pain killer.

Q. How long does Pisi 20mg Tablet work?

Pisi 20mg Tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Q. Can you get high by using Pisi 20mg Tablet?

No. Pisi 20mg Tablet is not known to cause high. It is a non-narcotic painkiller.

Q. Can Pisi 20mg Tablet be used to treat menstrual cramp?

Pisi 20mg Tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Q. Can I use Pisi 20mg Tablet for a migraine?

Pisi 20mg Tablet is not approved for the treatment of migraine. Research studies have shown that Pisi 20mg Tablet is effective in significantly decreasing the pain associated with migraine without aura.

Q. Is Pisi 20mg Tablet effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pisi 20mg Tablet as the cause of back pain can be different for different person.

Q. Is Pisi 20mg Tablet affective in gout management?

Yes. Pisi 20mg Tablet can be given for the treatment of acute gout. Research studies have shown Pisi 20mg Tablet to be highly effective in the treatment of acute gout.

Q. Can you donate blood when on the medication with Pisi 20mg Tablet?

Yes. You can donate blood when on Pisi 20mg Tablet. Do inform your doctor before donating blood.

Q. Can I use Pisi 20mg Tablet if I am a diabetic?

Pisi 20mg Tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pisi 20mg Tablet so taking piroxicam can lead to increased risk of renal failure by many folds.

Q. Can I use Pisi 20mg Tablet if I have a deranged renal function?

No. Pisi 20mg Tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Q. Can Pisi 20mg Tablet lead to skin reactions?

Yes. Pisi 20mg Tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Q. Can I use Pisi 20mg Tablet if I am pregnant?

No. Pisi 20mg Tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Q. Can I use Pisi 20mg Tablet if I have peptic ulcer disease?

No. Pisi 20mg Tablet is contraindicated in cases of active peptic ulcer disease. Pisi 20mg Tablet is known to cause gastric ulceration and bleeding.

Q. Can I use Pisi 20mg Tablet if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Can Pisi 20mg Tablet lead to difficulty in conception?

Yes. Pisi 20mg Tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Can Pisi 20mg Tablet be used with diuretics?

No. Pisi 20mg Tablet should not be used with diuretics. Pisi 20mg Tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can Pisi 20mg Tablet be used with lithium?

No. Pisi 20mg Tablet should not be used with lithium. Pisi 20mg Tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Q. Can Pisi 20mg Tablet be used with warfarin?

No. Pisi 20mg Tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Q. What increases the chances of getting a gastric ulcer when I am already taking Pisi 20mg Tablet?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pisi 20mg Tablet?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Q. What are the serious side effects of Pisi 20mg Tablet?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
  4. PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. ScienceDirect. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Piroxicam. Feb. 2015. [Accessed 02 Apr. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Evershine Lifesciences Pvt Ltd
Address: S. No. 33/1, 33 / 2, PWT, Near Shiwalik Garden, Manimajra, Chandigarh - 160101
Country of origin: India
Expires on or after: June, 2024

A licensed vendor partner from your nearest location will deliver Pisi 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

53.0160Get 12% OFF
46.17+ free shipping withCare Plan Logo
Inclusive of all taxes
This offer price is valid on orders above ₹1599. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹260. T&C apply.
10.0 tablets in 1 strip
Add to cart
Cash on delivery available
Earliest delivery by Saturday, 30 March
Delivering to:
110020, New DelhiDown Arrow Icon

Additional offers

Amazon Pay Later: Pay with Amazon Pay Later on Tata 1mg for Rs. 499 and more and earn cashback up to Rs. 300 with minimum cashback of Rs. 15. Offer ends 31st March'24.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.