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Piroxil 20mg Tablet DT

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Piroxil 20mg Tablet DT is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.

Piroxil 20mg Tablet DT should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.


Uses of Piroxil Tablet DT

Benefits of Piroxil Tablet DT

In Pain relief

Piroxil 20mg Tablet DT is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Piroxil Tablet DT

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Piroxil

  • Vomiting
  • Stomach pain
  • Nausea
  • Headache
  • Dizziness

How to use Piroxil Tablet DT

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Piroxil 20mg Tablet DT is to be taken with food.

How Piroxil Tablet DT works

Piroxil 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Piroxil 20mg Tablet DT.
Pregnancy
CONSULT YOUR DOCTOR
Piroxil 20mg Tablet DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Piroxil 20mg Tablet DT is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Piroxil 20mg Tablet DT may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Piroxil 20mg Tablet DT should be used with caution in patients with severe kidney disease. Dose adjustment of Piroxil 20mg Tablet DT may be needed. Please consult your doctor.
Liver
CAUTION
Piroxil 20mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Piroxil 20mg Tablet DT may be needed. Please consult your doctor.

What if you forget to take Piroxil Tablet DT?

If you miss a dose of Piroxil 20mg Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Piroxil 20mg Tablet DT
₹6.79/Tablet DT
₹5.7/tablet dt
16% cheaper
Mizocam Tablet DT
Leeford Healthcare Ltd
₹3.5/tablet dt
48% cheaper
Piroxinex 20mg Tablet DT
Intas Pharmaceuticals Ltd
₹6.25/tablet dt
8% cheaper
Doloforce -DT Tablet
Mankind Pharma Ltd
₹7.6/tablet dt
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₹6.9/tablet dt
2% costlier

Quick tips

  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Piroxil 20mg Tablet DT helps relieve pain and swelling of various joints and muscles.
  • Take it with food to avoid stomach upset.
  • Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
  • It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness. 

Fact Box

Chemical Class
Enolic acid Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)

Interaction with drugs

Taking Piroxil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of bleeding. Do not consume Acenocoumarol with Piroxicam. If concurrent use is essential, your doctor may monitor your treatment and adjust th... More
Concurrent use may result in fatal Methotrexate poisoning. Careful consideration is advised when taking Methotrexate with Piroxicam. Your doctor may monitor your treatment and adj... More
Concurrent use may increase the risk of serious damage to the kidneys. If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney ... More
Concurrent use may result in fatal Methotrexate poisoning. Careful consideration is advised when taking Methotrexate with Piroxicam. Your doctor may monitor your treatment and adj... More
Concurrent use may increase the risk of bleeding. Do not consume Phenindione with Piroxicam. If concurrent use is essential, your doctor may monitor your treatment and adjust the ... More

Patient concerns

arrow
One of my teeth is sensitive. It some times pains
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief
fever and 2 months pregnant can take combiflan
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
No take Crocin for pain relief
arrow

FAQs

What is the difference between Piroxil 20mg Tablet DT and diclofenac?

Both Piroxil 20mg Tablet DT and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piroxil 20mg Tablet DT.

What is the difference between Piroxil 20mg Tablet DT and naproxen?

Both Piroxil 20mg Tablet DT and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piroxil 20mg Tablet DT.

What is the difference between Piroxil 20mg Tablet DT and meloxicam?

Both Piroxil 20mg Tablet DT and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piroxil 20mg Tablet DT.

What is the difference between Piroxil 20mg Tablet DT and ketoprofen?

Both Piroxil 20mg Tablet DT and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piroxil 20mg Tablet DT. Ketoprofen gel also showed excellent tolerability.

What is the difference between Piroxil 20mg Tablet DT and tramadol?

Piroxil 20mg Tablet DT is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

What is the difference between Piroxil 20mg Tablet DT and nimesulide?

Both Piroxil 20mg Tablet DT and nimesulide are pain killers. However, Piroxil 20mg Tablet DT is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Can Piroxil 20mg Tablet DT be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piroxil 20mg Tablet DT or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piroxil 20mg Tablet DT.

Are Piroxil 20mg Tablet DT and aspirin same?

No. Piroxil 20mg Tablet DT and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can Piroxil 20mg Tablet DT be used along with dexamethasone?

No. Piroxil 20mg Tablet DT should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.

Can Piroxil 20mg Tablet DT be used with methocarbamol?

Yes. Methocarbamol can be used with Piroxil 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Piroxil 20mg Tablet DT be used along with paracetamol?

Yes. Paracetamol can be used with Piroxil 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Piroxil 20mg Tablet DT a NSAID?

Yes. Piroxil 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID).

Is Piroxil 20mg Tablet DT a sulfa drug?

Piroxil 20mg Tablet DT is a sulphur containing compound. Piroxil 20mg Tablet DT can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Is Piroxil 20mg Tablet DT a blood thinner?

No. Piroxil 20mg Tablet DT is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Is Piroxil 20mg Tablet DT a muscle relaxant?

No. Piroxil 20mg Tablet DT is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Is Piroxil 20mg Tablet DT a narcotic?

No. Piroxil 20mg Tablet DT is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Piroxil 20mg Tablet DT be used in hypertension?

No. Piroxil 20mg Tablet DT is not a medication to control hypertension. It is important to note that Piroxil 20mg Tablet DT decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piroxil 20mg Tablet DT.

Can Piroxil 20mg Tablet DT be used along with Losartan?

No. Piroxil 20mg Tablet DT should not be combined with Losartan. It is important to note that Piroxil 20mg Tablet DT decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxil 20mg Tablet DT.

Can Piroxil 20mg Tablet DT be used with Lisinopril?

No. Piroxil 20mg Tablet DT should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxil 20mg Tablet DT.

Can Piroxil 20mg Tablet DT be used with calcium channel blocker?

Yes. Piroxil 20mg Tablet DT can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Can Piroxil 20mg Tablet DT be used with Tizanidine?

Yes, Piroxil 20mg Tablet DT can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Why is beta cyclodextrin added to Piroxil 20mg Tablet DT?

Yes. Piroxil 20mg Tablet DT can be combined with beta-cyclodextrin. Research has shown that combining Piroxil 20mg Tablet DT with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Are there any alternatives of Piroxil 20mg Tablet DT?

Yes. There are alternatives to Piroxil 20mg Tablet DT. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

What are the contraindications for Piroxil 20mg Tablet DT?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can Piroxil 20mg Tablet DT be used in the treatment of allergy?

No. Piroxil 20mg Tablet DT is not a drug to treat allergy. It is a pain killer.

How long does Piroxil 20mg Tablet DT work?

Piroxil 20mg Tablet DT is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can you get high by using Piroxil 20mg Tablet DT?

No. Piroxil 20mg Tablet DT is not known to cause high. It is a non-narcotic painkiller.

Can Piroxil 20mg Tablet DT be used to treat menstrual cramp?

Piroxil 20mg Tablet DT is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Can I use Piroxil 20mg Tablet DT for a migraine?

Piroxil 20mg Tablet DT is not approved for the treatment of migraine. Research studies have shown that Piroxil 20mg Tablet DT is effective in significantly decreasing the pain associated with migraine without aura.

Is Piroxil 20mg Tablet DT effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Piroxil 20mg Tablet DT as the cause of back pain can be different for different person.

Is Piroxil 20mg Tablet DT affective in gout management?

Yes. Piroxil 20mg Tablet DT can be given for the treatment of acute gout. Research studies have shown Piroxil 20mg Tablet DT to be highly effective in the treatment of acute gout.

Can you donate blood when on the medication with Piroxil 20mg Tablet DT?

Yes. You can donate blood when on Piroxil 20mg Tablet DT. Do inform your doctor before donating blood.

Can I use Piroxil 20mg Tablet DT if I am a diabetic?

Piroxil 20mg Tablet DT in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Piroxil 20mg Tablet DT so taking piroxicam can lead to increased risk of renal failure by many folds.

Can I use Piroxil 20mg Tablet DT if I have a deranged renal function?

No. Piroxil 20mg Tablet DT should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Can Piroxil 20mg Tablet DT lead to skin reactions?

Yes. Piroxil 20mg Tablet DT is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Can I use Piroxil 20mg Tablet DT if I am pregnant?

No. Piroxil 20mg Tablet DT should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can I use Piroxil 20mg Tablet DT if I have peptic ulcer disease?

No. Piroxil 20mg Tablet DT is contraindicated in cases of active peptic ulcer disease. Piroxil 20mg Tablet DT is known to cause gastric ulceration and bleeding.

Can I use Piroxil 20mg Tablet DT if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can Piroxil 20mg Tablet DT lead to difficulty in conception?

Yes. Piroxil 20mg Tablet DT can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Piroxil 20mg Tablet DT be used with diuretics?

No. Piroxil 20mg Tablet DT should not be used with diuretics. Piroxil 20mg Tablet DT reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Can Piroxil 20mg Tablet DT be used with lithium?

No. Piroxil 20mg Tablet DT should not be used with lithium. Piroxil 20mg Tablet DT leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Can Piroxil 20mg Tablet DT be used with warfarin?

No. Piroxil 20mg Tablet DT should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What increases the chances of getting a gastric ulcer when I am already taking Piroxil 20mg Tablet DT?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Piroxil 20mg Tablet DT?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

What are the serious side effects of Piroxil 20mg Tablet DT?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
  4. PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  5. ScienceDirect. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Piroxicam. Feb. 2015. [Accessed 02 Apr. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link
  9. Piroxicam [Drug Label]. Mumbai, India: Pfizer Limited; 2022. [Accessed 06 Apr. 2024] (online) Available from: External Link

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