Medicine Overview of Piron Tablet
Piron 20mg Tablet is used in pain relief
. It relieves pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piron 20mg Tablet is to be taken with food.
Piron 20mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
In Depth Information on Piron Tablet
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
It should be taken with food or milk to avoid getting an upset stomach.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
Piron can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Piron Tablet related warnings
Taking Piroxicam with alcohol may increase your risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Piron 20mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Piron 20mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Piron 20mg Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Piron 20mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Piron 20mg Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Piron 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Piron 20mg Tablet may be needed. Please consult your doctor.
If you miss a dose of Piron 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Piron Tablet
Q. What is the difference between Piron and diclofenac?
Both Piron and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piron.
Q. What is the difference between Piron and naproxen?
Both Piron and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piron.
Q. What is the difference between Piron and meloxicam?
Both Piron and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piron.
Q. What is the difference between Piron and ketoprofen?
Both Piron and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piron. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Piron and tramadol?
Piron is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Piron and nimesulide?
Both Piron and nimesulide are pain killers. However, Piron is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piron or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piron.
No. Piron and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Piron be used along with dexamethasone?
No. Piron should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Piron be used with methocarbamol?
Yes. Methocarbamol can be used with Piron as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Piron be used along with paracetamol?
Yes. Paracetamol can be used with Piron as no serious side effects are known. Inform your doctor before starting any of the medication.
Yes. Piron is a non-steroidal anti-inflammatory drug (NSAID).
Piron is a sulphur containing compound. Piron can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
No. Piron is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
No. Piron is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
No. Piron is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
No. Piron is not a medication to control hypertension. It is important to note that Piron decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piron.
Q. Can Piron be used along with Losartan?
No. Piron should not be combined with Losartan. It is important to note that Piron decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piron.
Q. Can Piron be used with Lisinopril?
No. Piron should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piron.
Q. Can Piron be used with calcium channel blocker?
Yes. Piron can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Piron be used with Tizanidine?
Yes, Piron can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Yes. Piron can be combined with beta-cyclodextrin. Research has shown that combining Piron with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Yes. There are alternatives to Piron. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
No. Piron is not a drug to treat allergy. It is a pain killer.
Piron is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
No. Piron is not known to cause high. It is a non-narcotic painkiller.
Piron is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Piron is not approved for the treatment of migraine. Research studies have shown that Piron is effective in significantly decreasing the pain associated with migraine without aura.
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Piron as the cause of back pain can be different for different person.
Yes. Piron can be given for the treatment of acute gout. Research studies have shown Piron to be highly effective in the treatment of acute gout.
Yes. You can donate blood when on Piron. Do inform your doctor before donating blood.
Piron in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Piron so taking piroxicam can lead to increased risk of renal failure by many folds.
No. Piron should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Yes. Piron is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
No. Piron should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
No. Piron is contraindicated in cases of active peptic ulcer disease. Piron is known to cause gastric ulceration and bleeding.
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Yes. Piron can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Piron be used with diuretics?
No. Piron should not be used with diuretics. Piron reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Piron be used with lithium?
No. Piron should not be used with lithium. Piron leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Piron be used with warfarin?
No. Piron should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Severely interacts with other drugs like
Taking Piron with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Oxyphenbutazone: Sioril
Medicines with composition Nimesulide: Edil, Zelid, Nimusid, Neede, Nimujet, Twinease, Nyci, Nise, Nobel, Nimtus, Spinn, Nimbond, Nimbus, Redynise, Nizer, Denim Juicy, Pyrifen Gel, Hilid P, Nicip, Myonal, Nimtech, Nelsid, Nimusol, Curenim, Biogesic, Nulide, Angip, Nisel TD, NM, Nimeson, Nimutab, Pronim, Nimodol, Nimi Rapi, Relisulide, Nimprex, Zydol, I Nid, Nimdis, Mazic, Emsulide, Nimol, Nugesic, Nimeron, Pyrimide, Nimuvin, Jumolid, Nimeka, Nimotil, Bionim, Nimstal, Arsulide, Lupisulide, Nimusen, Nimcare, Nemu, Nimd, Nimcet, Supernim, Nimind CT, Ginim, Nimpus, Nalgis, Nimlodi, Nimmi, Zega, Unik Junior, Patalgin, Nimtaz, Doly, Numel, Needfast, Nimrod, Pyrestat, Subid, Vylid, Milenim, Nixia, Orange N, Nimupain, Gersulide, Nimdus, Doloflam, Knott, Neulab, Nex Kid, Nimik, Nimu, Olnim, Orthogesic, Novolid, Remulide, Nimind, Tremolide, Nimi, Zynimo, Auronim, Novogesic, Nimcell, Sidlide, Nimiz, Eusel, Nimeter, Nmd, Oflapoon, Resinim Plus, Arthorid, Mesulid, Nimaid, Nimcee, Nimdex, Nimobid, Nimoflam, Nimowen, Nimuspa, Niq, Nimulet, Nimisan, Nimrest, Gesnim, Nex MD, Nimopin, Toli, Flenim Plus, Nexmac, Nilide, Nex, Nimus, Nuleb, Pansulide RD, Redfast, Misogesic, Aglonim, Flenim MR, Instanim, Naba P, Nemunac, Nimugee, Spanim, New Nicip, Nimo P, Nimtop, Corfen NS, Mylid, Neosaid, Nimulid, Vylid ID, Nimumac, Minidol, Nilup, Nimek, Nimo, Pirodol, Niltel Fast, Dolonim, Enlide, Pyrisulide, Infanim, Dynalid, Nilpain, Nimecon, Nimutec, Nipace, Resinim, Ortinims, I Nid Aio, Nimace, Nimfast, Soonil, Denim Kid, Actinim, Nimogen, Nimos, Nimular, Geeflam, Kazolid, Numed, Painulide, Nuaid, Dolide, Nimeb, Nimogem, Nimujet Bcd, Nimvista, Nisulid, Aulin, Nimlin, Nimpic, Aurolide, Nicare, Nim, Nimbet, Nimitis, Nimcox, Embulide, Mangolide, Naba, Nemosif, Solide, Flenim, Genlide, Nimjet, Nimuwin, Nise Mdt, Anafebrin, Nimbid, Nimotrin, Nimcet Juicy, Arpinim, Jumolid Kid, Orange N Juicy, Ranter, Pazz, Neopar, Disnim, Nimulet Kid, Nide, Blisulide, Nimsa, Nimucon, Nimuda, Nisul, Nyde, Nimford, Neulite S, Nimopen, Nimez, Nimuflam, Takeaway, Nimtop P, Nimular SP, Denim, Nimica, Nimumed, Nimegesic, Nimotas CD, Nimotas Kid, Zonim, Nam, Ransulide, Nimulex, Neemact, Neosulide, Ladex, Nimax, Nimcart, Trulide, Nimuzen, Nemopar, Megagesic, Zenim, Nimter, Nizapas, Nemon, Azonim, Neemo, Nimoks, Nimsac, Namosid, Fonim, Nimip, Asilid, Nimtin, Sialid, Nesufen, Nimlid-MD, Sulid, Delnim, Nimley, Nimlak, Nimven
One of the following vendor pharmacies will deliver Piron 20mg Tablet: PMA, ARD, HTS, TNH, ZVP, SGC, NVL, OHM, BHM, ATP, SVH, RWP, HIP, SYN, HMP, NWP, MSD, AAR, KHC, BHP, IAD, AWS, OWP, RSS, NNP, KHH, RUS, SLN, MAP, OIP, EPS, FGH, MAM, HZF, TFP, BIO, SPD, SSA, OLT, EQN, SBL, JHC, BAP, BDN, WHL, ESY, DHR, JBT, DZY, IPL, AGT, SJP, ANT, BTM, TOM, BAL, SMN, PEN, RPP, PPR, EVP, RKS, JSL, KMC, DPL, UBL, SGH, WSI, BBS, MLC, GBL, SHD, SHC, GTC, USF, HEX, HGI, THP, AAY, HPC, BMJ, RDH, DPP, BSN, VRS, DVH, VJS, PTI, MDO, ADT, TRP, KIS, ABP, RJH, AYU, EMB, HAT, SWP, BLS, RSA, RDR, AVS, ATL, NNH, BLE, 9T9, DGN, STA, JIV, HSP, RHW, JVN, PNT, NDP, SWA, UMP, LHA, NTB, LCC, ZEL, QLF, RHL, NSL, PLT, DHP, NVY, MDH, HNP, NXG, GTK, RPI, SDM, P2P, QTM, GHR, NAS, SAF, MAX, JVO, AMR, BHS, MMS, DAO, PWN, VNS, BGS, HBV, PRN, CHP, ZPR, VDH, GPP, SVS, CLT, SRG, AYM, SBA, INC, SCH, PVP, DYG, MAK, DFP, ENP, LMS, GPT, MPC, GNC