Periset Injection

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)
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Introduction

Periset Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Periset Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you appropriate dose depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections. 

The most common side effects of taking this medicine include injection site pain, headache, and constipation. These symptoms should disappear when you stop taking the medicine.  But, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Periset Injection

Benefits of Periset Injection

In Nausea

Periset Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy in adults as well as children. This medicine helps you recover more comfortably from these treatments. Periset Injection is also effective at preventing nausea and vomiting after an operation. Periset Injection is given as an injection by a doctor, in the dose that is best for you, depending on the condition you are being treated for. Do not self-administer this medicine to avoid any undesirable side effects.

Side effects of Periset Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Periset

  • Headache
  • Constipation
  • Injection site pain

How to use Periset Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Periset Injection works

Periset Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Periset Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Periset Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Periset Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Periset Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Periset Injection is safe to use in patients with kidney disease. No dose adjustment of Periset Injection is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Periset Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Periset Injection?

If you miss a dose of Periset Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Periset Injection
₹12.81/Injection
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Domi UP 2mg Injection
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₹11.8/Injection
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Ranidom ON 2mg Injection
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Quick Tips

  • You have been prescribed Periset Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It is given as an injection into veins or as drip under the supervision of a doctor.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
  • It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin antagonists (5-HT3 antagonists)

Interaction with Drugs

Taking Periset with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Acicod, Montokuf, Codine Sulphate
SERIOUS
Brand(s): Parvodex
SERIOUS
Brand(s): Nalfy, Nacphin, Ruffy
SERIOUS
Brand(s): Wintal
SERIOUS

Patient Concerns

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SIR/MAM, I AM 5 MOnths pregnant.Taking periset MD ondensteron since 2nd months.Till date if I don't take medicine,too much vomiting starts. SO I HAVE TO CONTINUE.Is it safe to take it during pregnancy. I think my stomach habituated with this medicine. Pls suggest.I m feeling worried.
Dr. Megha Tuli
Obstetrics and Gynaecology
There is no dependence on this medicine. Do not worry. Very soon the vomiting will wean off and then you can leave the medicine.
What is side effect of primolut n
Dr. Megha Tuli
Obstetrics and Gynaecology
Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
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FAQs

Q. How quickly does Periset Injection work?

Periset Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Periset Injection?

The most common side effects of Periset Injection are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Q. Is Periset Injection a steroid?

No, Periset Injection is an antiemetic and not a steroid. Periset Injection is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Q. Does Periset Injection work for seasickness?

No, Periset Injection does not work for seasickness. This is because Periset Injection has very little effect on the nausea associated with motion sickness.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. MedlinePlus. Ondansetron. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Country of Origin: India

Expires on or after: July, 2021

A licensed vendor partner from your nearest location will deliver Periset Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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2 ml in 1 vial
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