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03 Jul 2020 | 05:13 PM (IST)
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Pentogra 40mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Pentogra 40mg Tablet is a medicine used to treat high blood pressure in the blood vessels that supply the lungs (pulmonary arterial hypertension). It relieves breathlessness and improves exercise capacity in men and women. This slows down the progression of your illness.

Pentogra 40mg Tablet belongs to a group of medicines known as phosphodiesterase type 5 (PDE 5) inhibitors. It may be taken on an empty stomach or with a meal, but it should be taken at a fixed time each day. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. Follow the advice of your doctor. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may lead to the worsening of your condition.

The most common side effects of this medicine are flushing (sense of warmth), headache, nosebleeds, blurred vision, indigestion, difficulty in sleeping, and rash. Talk to your doctor if any of the side effects bother you or do not go away.

This medicine can be dangerous to take along with medicines called nitrates (often given for chest pain). Do not take this medicine if you have severe heart or liver problems, if you have recently had a stroke or heart attack or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems. Pregnant or breastfeeding women should also consult their doctor before taking it. You should not drive if this medicine makes you feel dizzy. Avoid drinking alcohol while taking this medicine as it increases the chances of side effects.

Benefits of Pentogra Tablet

In Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain, and swelling in your ankles and legs. It is caused by the thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Pentogra 40mg Tablet belongs to a group of medicines called PDE5 inhibitors. It works by relaxing blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy. Take it regularly, as prescribed even if you think it is not working or if you feel better.

Side effects of Pentogra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentogra

  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache

How to use Pentogra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentogra 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pentogra Tablet works

Pentogra 40mg Tablet is a phosphodiesterase (PDE-5) inhibitor. It works by relaxing the blood vessels in your lungs thereby reducing the high blood pressure in the lungs. This allows your heart to work less to pump blood in your lungs.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pentogra 40mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Pentogra 40mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Pentogra 40mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Pentogra 40mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pentogra 40mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Pentogra 40mg Tablet is recommended.
However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated.
Liver
CAUTION
Pentogra 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Pentogra 40mg Tablet may be needed. Please consult your doctor.
There is limited information available on the use of Pentogra 40mg Tablet in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Pentogra 40mg Tablet is used to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
  • It can help improve your quality of life and exercise ability.
  • Pentogra 40mg Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Do not use other medicines (nitrates or nitroglycerin) when taking Pentogra 40mg Tablet as it could drop your blood pressure to a dangerous level.
  • Do not consume alcohol while taking Pentogra 40mg Tablet as that may increase the blood pressure-lowering effects of Pentogra 40mg Tablet.
  • Stop taking Pentogra 40mg Tablet and immediately inform your doctor if you notice loss of vision in one or both eyes or sudden loss of hearing with ringing sensation in your ear.
  • If you have an erection, which lasts continuously for more than 4 hours, stop taking Pentogra 40mg Tablet and contact your doctor immediately.
  • Do not stop taking the medication suddenly without talking to your doctor as that may lead to worsening of your symptoms.

Fact Box

Chemical Class
Benzenesulfonamide Derivative
Habit Forming
No
Therapeutic Class
SEX STIMULANTS REJUVENATORS

Interaction with Drugs

Taking Pentogra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Leonite, Isonit GTN, Nitrogal
LIFE-THREATENING
Brand(s): Isocrate, Cardicap, Sorbidine
LIFE-THREATENING
Brand(s): Monopark, Isotrate, Angitrate
LIFE-THREATENING
Brand(s): Lorandil
LIFE-THREATENING

Patient Concerns

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Hiii my wife having hurt patient ( pulmonary hypertension ) she's taking pulmonext 5mg tablet but this tablet is very costly for me of Rs. 1450/- 10tab. I want to know any another tablet available in same drugs with low price
Dr. Sfurti Mann
Internal Medicine
This can't be decided online Your doctor is the best judge about your patients pulmonary hypertension
Having high Pulmonary Atrial Hypertension
Dr. Nabajit Talukdar
Cardiology
What medicines r u on
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Do you have any questions related to Pentogra 40mg Tablet ?

FAQs

Q. Can I get Pentogra 40mg Tablet without a prescription?

No, you need a doctor's prescription to get Pentogra 40mg Tablet since it is a prescription medicine. Your doctor will prescribe it only if they judge that it would be beneficial for you.

Q. Can I take Pentogra 40mg Tablet with paracetamol?

Yes, Pentogra 40mg Tablet can be taken with paracetamol. No interactions between the 2 medicines or any harmful effects have been reported when they are used together.

Q. Can I take Pentogra 40mg Tablet for the rest of my life?

Pentogra 40mg Tablet is a prescription medicine and should only be taken for the duration that is advised by your doctor.

Q. Why is the use of Pentogra 40mg Tablet contraindicated with nitrates?

Use of Pentogra 40mg Tablet is harmful for patients taking nitrates or blood pressure-lowering medicines as their combined use can cause a severe fall in blood pressure, which can also result in death. However, if these medicines are to be taken together then it is advised to keep a time gap of 24 hours between the intake of Penegra and blood pressure-lowering medicines.

Q. Why does Pentogra 40mg Tablet cause a fall in blood pressure (hypotension)?

Pentogra 40mg Tablet has the property of relaxing the smooth muscle of the blood vessels and widening them which can cause a fall in blood pressure (hypotension). So, when used with blood pressure lowering medicines or nitrates, it can cause a severe fall in blood pressure, which could be fatal. Pentogra 40mg Tablet should not be taken if you are taking nitrates for chest pain or you have a history of heart attack or stroke in the past 6 months.

Q. Is Pentogra 40mg Tablet safe to use in patients with diabetes?

Yes, if prescribed by your doctor then Pentogra 40mg Tablet is safe to use in patients with diabetes.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 752-53.
  2. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 197.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1261-62.
  4. Drugs.com. Sildenafil. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Sildenafil. New York, New York: Pfizer; 1998 [revised Mar. 2014]. [Accessed 04 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

2F, Ameebazar, B/h, Jyotisangh Pattharkuwa, Relief Road, Ahmedabad - 380 001
Best Price
₹55.25
MRP65  Get 15% OFF
Valid only on the orders above ₹499
4 tablets in 1 strip
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