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Pbquin 300mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 14 Apr 2026 | 04:20 PM (IST)
Pbquin 300mg Tablet is an antiparasitic medicine, used for the treatment of malaria. It may also be used to treat and prevent nighttime leg cramps. It works by killing the malaria-causing parasite and stops the infection from spreading.
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Pbquin 300mg Tablet
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General Information

The content is shown in English
Pbquin 300mg Tablet image
Pbquin 300mg Tablet image

Product introduction

Pbquin 300mg Tablet should be used in the dose and duration as advised by your doctor. Take it with food to decrease the risk of stomach upset. Do not skip any doses and finish the full course of treatment even if you feel better. Take measures to reduce the chance of being bitten by mosquitoes like using insect repellent creams and mosquito repellent sprays.

Some people may experience vomiting, headache, and dizziness as side effects of this medicine. Please consult your doctor if these persist for a longer duration. Inform your doctor if you have a history of fits (seizures) or any problems with your kidney, heart, or liver.

Inform your doctor if you have diabetes as Pbquin 300mg Tablet can lower the sugar levels in the blood. If you are diabetic, monitor your blood sugar regularly. It may cause blurring of vision. Therefore, regular eye examinations are recommended while on treatment with this medicine. When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.

Uses of Pbquin Tablet

Benefits of Pbquin Tablet

Malaria
Pbquin 300mg Tablet is an antimalarial medicine and is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes). However, this medicine should not be used to prevent malaria or to treat severe cases of malaria. Take it only as prescribed and refrain from taking any other medicines or antacids along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.

Side effects of Pbquin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pbquin
  • Vomiting
  • Deafness
  • Headache
  • Dizziness
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Blurred vision
  • Nausea
  • Abdominal pain
  • Ringing in ear
  • Diarrhea
  • Vertigo
  • Increased sweating

How to use Pbquin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pbquin 300mg Tablet should be taken with or after food.

How Pbquin Tablet works

Pbquin 300mg Tablet is an antiparasitic medication which treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Quick tips

  • Pbquin 300mg Tablet helps in the treatment of malaria.
  • Take it as per the dose and duration prescribed by your doctor. Taking too much of this medicine may lead to serious, irreversible side effects.
  • Take it with food to avoid an upset stomach.
  • Do not drive or do anything that requires mental focus until you know how Pbquin 300mg Tablet affects you.
  • Have regular eye tests done while you are taking this medicine. Stop taking Pbquin 300mg Tablet and immediately inform your doctor if you notice any changes in your vision.
  • Inform your doctor if you develop a rash or ringing in your ears.
  • It can cause lowering of blood sugar level. Inform your doctor if you experience symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Pbquin 300mg Tablet should be taken on an empty stomach.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Tips to reduce the chance of being bitten by mosquitoes:
    • Wear light-colored and covered clothing when you are outside after sunset.
    • Use insect repellent creams or sprays on parts of your body not covered by clothing.
    • Spray to kill any mosquitoes that may have entered rooms in spite of screening.
  • If you vomit within 1 hour of taking the tablets, take another dose. 
  • Inform your doctor if you have kidney liver or heart disease.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pbquin 300mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Pbquin 300mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pbquin 300mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Pbquin 300mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pbquin 300mg Tablet may affect your vision and cause vertigo (dizziness or spinning sensation) which may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Pbquin 300mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Pbquin 300mg Tablet in patients with liver disease.

Interaction with drugs

Taking Pbquin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Quinine.
Life-threatening

Escitalopram Oxalate (Oral Route)

Do not consume Escitalopram Oxalate with Quinine.
Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Quinine.
Life-threatening

Haloperidol (Oral Route)

Do not consume Haloperidol with Quinine.
Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Quinine.

Frequently asked questions

Use of Pbquin 300mg Tablet should be avoided in patients who are allergic to Pbquin 300mg Tablet or any of its components. However, if you are not aware of any allergy or if you are using Pbquin 300mg Tablet for the first time, consult your doctor.
Before starting treatment with Pbquin 300mg Tablet, inform your doctor if you have any other health conditions like kidney or heart-related problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Also, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant or breastfeeding.
Pbquin 300mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
If you forget a dose of Pbquin 300mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
No, do not stop taking Pbquin 300mg Tablet without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
Symptoms of malaria can develop as quickly as 7 days after you are being bitten by an infected mosquito. Typically, the time between being infected and the appearance of symptoms (incubation period) is 7 to 18 days. However, in some cases it can take up to one year for the symptoms to develop. Initial symptoms of malaria are flu-like which include feeling hot and shivery, muscle pains, vomiting, headaches and diarrhea.
Malaria can be avoided by taking the right approach towards prevention. Avoid mosquito bites by covering your arms and legs, using mosquito net and insect repellent. Check with your doctor whether you need to take malaria prevention tablets. If you do, make sure you take the right antimalarial tablets at the right dose, and finish the proper course of treatment. Seek immediate medical advice from the doctor if you have malaria symptoms.
Pbquin 300mg Tablet should be used with caution in patients having an impaired kidney function. Do not self medicate and avoid its use. If the impairment is very severe then the use of this medicine should be avoided. Therefore, inform your doctor before taking Pbquin 300mg Tablet.
No, the use of Pbquin 300mg Tablet is not recommended during pregnancy as it may harm your unborn baby. Seek proper advice from your doctor on using this medicine, if you are pregnant.

Fact Box

Chemical Class

Cinchona alkaloids

Habit Forming

No

Therapeutic Class

ANTI MALARIALS

Action Class

Other Antimalarial Agents

References

  1. Vinetz JM, Clain J, Bounkeua V, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1405-407.
  2. Rosenthal PJ. Antiprotozoal Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 905-906.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1188.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: P & B Pharmaceuticals Ltd
Address: A/09, Ashirwad,11 Lokhandwala Complex, Andheri (W), Mumbai-400 053.

Vendor Details

Country of origin: India
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