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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Pause 500mg Injection


Overview

Introduction

Pause 500mg Injection is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleed and in any oral, prostate or bladder surgery.

Pause 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of clots which leads to stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy from this injection.

The most common side effects may be injection site reactions such as pain, swelling and redness or pain in muscle, bone or joint. Inform your doctor if you have undergone any cardiac surgery or you are suffering from any kidney disease.

This injection is safe to use in pregnant or breastfeeding mothers. It is also safe to use in patients suffering from liver diseases. Caution is advised to drive after the administration of this injection.

Uses of Pause Injection

Side effects of Pause Injection

Common
  • Tiredness
  • Injection site reactions (pain, swelling, redness)
  • Nasal congestion (stuffy nose)
  • Musculoskeletal (bone, muscle or joint) pain

How to use Pause Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pause Injection works

Pause 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods, or after surgery.

Safety Advice

Alcohol
UNSAFE
Pause 500mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Pause 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Pause 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Pause 500mg Injection does not usually affect your ability to drive.
Kidney
CAUTION
Pause 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pause 500mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pause 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pause 500mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Pause Injection?

If you miss a dose of Pause 500mg Injection, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Pause 500mg Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
  • It is given as a slow injection into a vein.
  • Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
  • Your doctor may monitor your vision regularly while you are taking this medicine.
  • Inform your doctor if you have a history of kidney or liver disease.

Patient Concerns

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I was 6 weeks pregnant. Few days back I had mild vaginal bleeding. When I contacted my doctor she prescribed me PAUSE 500MG TABLET. The next day I had miscarriage. Did it happened because of consuming PAUSE 500MG TABLET?
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
What is there in pauseUsually doesn't happen with tablet
Hii mam 4 mnth started for pregnancy but tdy we had intercourse nd then agter that bleeding started ruk ruk ke pause 500 taken is sm thing to worry nt scan report is fine.hucog inj 5000 iu also taken pls reply i m 35 yrs old pls reply
Dr. Megha Tuli
Obstetrics and Gynaecology
Bleeding during pregnancy is not a good thing. Pause 500 will not really help alone. Progesterone injections weekly along with oral progesterone support should be started.
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Do you have any questions related to Pause 500mg Injection ?

User Feedback


FAQs

Q. Can Pause be given or injected into muscles?

No, Pause should not be administered by injection into the muscles. It should be given strictly through slow injection into the veins to prevent side effects.

Q. Is Pause dangerous?

Every medicine has its own side effects and these side effects are unlikely to happen if taken as directed. Usually, the benefits of the medicine are greater than the risk of side effects. Pause can rarely cause serious side-effects which can be dangerous, like anaphylaxis (red and lumpy skin rash, difficulty breathing, swelling of face, mouth, lips or eyelids), clot in another part of the body or eye problems. Do consult your doctor before you start this medication and follow the instructions strictly as given.

Q. Can Pause cause DVT?

Yes, Pause promotes blood clotting, thereby preventing blood loss. However, in rare cases, this can lead to a chance of developing a clot in the deep leg veins, a condition known as deep vein thrombosis (DVT). Although many research studies have shown that the increased risk of clot can be due to some other additional factors rather than Pause itself. This condition has been found to be more common in female patients taking Pause. Do consult your doctor before you start this medication and follow the instructions strictly as given.

Q. Can Pause affect the colour vision of eyes?

Yes, there are chances of possible disturbances in your colour vision when you are on long term treatment with Pause. Hence, regular eye check should be done during treatment and doctor should be informed if you notice any change in your vision. If any changes are seen your doctor may stop the medicine and suggest an alternative.

Q. Can Pause be taken safely in patients with kidney impairment?

Yes, Pause can be used in patients with kidney disease. Before starting this medication inform the doctor about any kidney-related problem. The doctor may suggest blood tests which will determine the functionality of your kidney, and accordingly the dose of the medicine will be adjusted.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 602.External Link
  2. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics.12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 867-68.External Link
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1388-89.External Link
  4. Tranexamic Acid. London, UK: ADVANZ Pharma; 2013 [revised 5 Jul. 2018]. [Accessed 17 Apr. 2019] (online) Available from:External Link
  5. Tranexamic Acid. New York, New York: Pharmacia & Upjohn Co.; 2011. [Accessed 07 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
255/2, Hinjawadi, Pune - 411057, India
A licensed vendor partner from your nearest location will deliver Pause 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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