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Last updated
08 Jun 2022 | 03:08 AM (IST)

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Pause 500mg Injection

Prescription Required

Product introduction

Pause 500mg Injection is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleed, and in any oral, prostate, or bladder surgery.

Pause 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of clots which leads to the stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy to this injection.

The most common side effects of this medicine include injection site reactions, tiredness, musculoskeletal pain, and nasal congestion. Inform your doctor if you have undergone any cardiac surgery or you are suffering from any kidney disease. This injection is safe to use in pregnant or breastfeeding mothers. It is also safe to use in patients suffering from liver diseases.

Uses of Pause Injection

Benefits of Pause Injection

In Treatment of Bleeding

Bleeding occurs when blood clots break down rapidly. Pause 500mg Injection reduces bleeding by preventing the rapid breakdown of clots. It helps to prevent excessive loss of blood, stops bleeding, and enhances the healing process. Bleeding can make you feel weak so it is advisable to take a good diet depending on your condition and with a doctor’s consultation.

Side effects of Pause Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pause

  • Musculoskeletal (bone, muscle or joint) pain
  • Joint pain
  • Headache
  • Back pain
  • Vomiting
  • Nausea
  • Abdominal pain
  • Fatigue
  • Diarrhea
  • Hypotension (low blood pressure)
  • Sinus disorder
  • Nasal discomfort
  • Muscle cramp
  • Migraine
  • Anemia (low number of red blood cells)
  • Allergic dermatitis
  • Lightheadedness
  • Thromboembolism

How to use Pause Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pause Injection works

Pause 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods, or after surgery.

Safety advice

Alcohol
UNSAFE
Pause 500mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Pause 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Pause 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pause 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Pause 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pause 500mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pause 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pause 500mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Pause Injection?

If you miss a dose of Pause 500mg Injection, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pause 500mg Injection
₹78.55/Injection
Texakind 500mg Injection
Mankind Pharma Ltd
₹44.19/injection
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Tenexa 500mg Injection
Molekule India Pvt Ltd
₹46/injection
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₹48.68/injection
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Tranlok 500mg Injection
Aristo Pharmaceuticals Pvt Ltd
₹56.96/injection
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Tramix 500mg Injection
Vhb Life Sciences Inc
₹70/injection
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Quick tips

  • Pause 500mg Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
  • It is given as a slow injection into a vein.
  • Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
  • Your doctor may monitor your vision regularly while you are taking this medicine.

Fact Box

Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Antifibrinolytic

Patient concerns

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I was 6 weeks pregnant. Few days back I had mild vaginal bleeding. When I contacted my doctor she prescribed me PAUSE 500MG TABLET. The next day I had miscarriage. Did it happened because of consuming PAUSE 500MG TABLET?
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
What is there in pauseUsually doesn't happen with tablet
Hii mam 4 mnth started for pregnancy but tdy we had intercourse nd then agter that bleeding started ruk ruk ke pause 500 taken is sm thing to worry nt scan report is fine.hucog inj 5000 iu also taken pls reply i m 35 yrs old pls reply
Dr. Megha Tuli
Obstetrics and Gynaecology
Bleeding during pregnancy is not a good thing. Pause 500 will not really help alone. Progesterone injections weekly along with oral progesterone support should be started.
arrow

User feedback


FAQs

Q. Can Pause 500mg Injection be given or injected into muscles?

No, Pause 500mg Injection should not be administered by injection into the muscles. It should be given strictly through slow injection into the veins to prevent side effects.

Q. Is Pause 500mg Injection dangerous?

Every medicine has its own side effects and these side effects are unlikely to happen if taken as directed. Usually, the benefits of the medicine are greater than the risk of side effects. Pause 500mg Injection can rarely cause serious side-effects which can be dangerous, like anaphylaxis (red and lumpy skin rash, difficulty breathing, swelling of face, mouth, lips or eyelids), clot in another part of the body or eye problems. Do consult your doctor before you start this medication and follow the instructions strictly as given.

Q. Can Pause 500mg Injection cause DVT?

Yes, Pause 500mg Injection promotes blood clotting, thereby preventing blood loss. However, in rare cases, this can lead to a chance of developing a clot in the deep leg veins, a condition known as deep vein thrombosis (DVT). Although many research studies have shown that the increased risk of clot can be due to some other additional factors rather than Pause 500mg Injection itself. This condition has been found to be more common in female patients taking Pause 500mg Injection. Do consult your doctor before you start this medication and follow the instructions strictly as given.

Q. Can Pause 500mg Injection affect the colour vision of eyes?

Yes, there are chances of possible disturbances in your colour vision when you are on long term treatment with Pause 500mg Injection. Hence, regular eye check should be done during treatment and doctor should be informed if you notice any change in your vision. If any changes are seen your doctor may stop the medicine and suggest an alternative.

Q. Can Pause 500mg Injection cause pulmonary embolism?

Pause 500mg Injection promotes blood clotting and can rarely cause blood clot to travel to the lungs (pulmonary embolism) which can turn fatal sometimes. Pulmonary embolism is not a common side effect in patients taking Pause 500mg Injection but can occur in overdosing, patients with long bedrest or prone individuals. Evidence suggests that the increased risk of clot can be due to some other additional risk factors as well.

Q. Can you take Pause 500mg Injection on an empty stomach?

Pause 500mg Injection can be taken with or without food with a glass of water. The medicine should be swallowed as a whole and should not be crushed or chewed.

Q. Can I take Pause 500mg Injection for more than 5 days?

The dose and duration of this medicine is decided by the type of disease for which it is prescribed. For heavy bleeding during monthly menstruation, it is usually taken for up to 5 days. For other conditions it can be prescribed for less than 5 days and even more that 5 days which is decided by the prescribing physician.

Q. Does Pause 500mg Injection affect fertility?

No, Pause 500mg Injection does not affect fertility. It is taken for heavy menstrual bleeding and evidence suggests no interference of this medicine with ovulation (release of eggs from the ovaries). Therefore, this medicine is not a type of contraceptive medicine and it will not affect your chances of becoming pregnant.

Q. Can Pause 500mg Injection be taken for nose bleeding?

Yes, Pause 500mg Injection can be used for nose bleeding. It helps to clot the blood and prevent bleeding. If the bleeding is frequently observed then the medicine can be even taken for a week.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 602.External Link
  2. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics.12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 867-68.External Link
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1388-89.External Link
  4. Tranexamic Acid. London, UK: ADVANZ Pharma; 2013 [revised 5 Jul. 2018]. [Accessed 17 Apr. 2019] (online) Available from:External Link
  5. Tranexamic Acid. New York, New York: Pharmacia & Upjohn Co.; 2011. [Accessed 07 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Country of origin: India
Expires on or after: December, 2023

A licensed vendor partner from your nearest location will deliver Pause 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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