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Patroxta 12.5 Tablet PR

Paroxetine (12.5mg)

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Patroxta 12.5 Tablet PR is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is used to treat major depression and anxiety-related conditions like obsessive-compulsive disorder and panic disorder.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Dec 2025 | 11:03 PM (IST)

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General Information

Contains

Paroxetine (12.5mg)

Marketer

Arinna Lifescience Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Patroxta 12.5 Tablet PR can be taken with or without food. The dose and how often you need to take the medicine will be decided by your doctor. They may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse, or you may suffer from unpleasant withdrawal symptoms such as anxiety, restlessness, palpitations, dizziness, and sleep disturbances.

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Patroxta 12.5 Tablet PR include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Inform your doctor about all the medicines you are taking to ensure safety.

Uses of Patroxta Tablet PR

Treatment of Major Depression
Treatment of Obsessive-compulsive disorder
Treatment of Panic disorder

Benefits of Patroxta Tablet PR

Treatment of Major Depression
Patroxta 12.5 Tablet PR helps improve symptoms of major depression by lifting mood, restoring interest in daily activities, and reducing feelings of sadness or hopelessness. It supports better emotional balance over time, which can enhance overall functioning and quality of life.

Treatment of Obsessive-compulsive disorder
In obsessive-compulsive disorder (OCD), Patroxta 12.5 Tablet PR helps reduce the intensity and frequency of persistent thoughts and the urge to perform repetitive actions. This makes it easier for individuals to manage daily tasks and experience relief from the distress caused by these symptoms.

Treatment of Panic disorder
Patroxta 12.5 Tablet PR helps people with panic disorder by reducing the number and severity of panic attacks. It also helps ease the constant worry about having another attack. This helps the individuals to feel more in control and comfortable in situations they may have previously avoided.

Side effects of Patroxta Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Patroxta

Fatigue
Dryness in mouth
Loss of appetite
Increased sweating
Nervousness
Low sexual desire
Insomnia (difficulty in sleeping)
Confusion
Yawning
Nausea
Tremors
Constipation
Erectile dysfunction
Delayed ejaculation
Decreased libido
Dizziness

How to use Patroxta Tablet PR

Use it as advised by your doctor or check the label for directions before use. Patroxta 12.5 Tablet PR may be taken with or without food.

How Patroxta Tablet PR works

Patroxta 12.5 Tablet PR is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder and obsessive-compulsive disorder.

All substitutes for Patroxta 12.5 Tablet PR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It can take 2-3 weeks for Patroxta 12.5 Tablet PR to start working.
Do not stop treatment suddenly, as this may cause upset stomach, flu-like withdrawal symptoms, and sleep disturbance.
If your doctor asks you to stop Patroxta 12.5 Tablet PR, you should reduce the dose slowly over 4 weeks.
Avoid consuming alcohol when taking Patroxta 12.5 Tablet PR, as it may cause excessive drowsiness and calmness.
The addiction/dependence potential of Patroxta 12.5 Tablet PR is very less.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Patroxta 12.5 Tablet PR

Pregnancy

UNSAFE

Patroxta 12.5 Tablet PR is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Patroxta 12.5 Tablet PR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Patroxta 12.5 Tablet PR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Patroxta 12.5 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Patroxta 12.5 Tablet PR should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Patroxta with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Paroxetine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.

Life-threatening

Zolmitriptan (Nasal Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Paroxetine. If Tranylcypromine is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.

Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Paroxetine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Paroxetine. Please consult your doctor.

Frequently asked questions

After how many days of taking Patroxta 12.5 Tablet PR will I start feeling better?

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.

I feel that my symptoms have worsened after having started taking Patroxta 12.5 Tablet PR. Can I stop it on my own or do I need to consult the doctor?

No, do not stop taking Patroxta 12.5 Tablet PR abruptly, without consulting your doctor. This is a common problem with Patroxta 12.5 Tablet PR that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.

Can Patroxta 12.5 Tablet PR affect my sex life?

Yes, Patroxta 12.5 Tablet PR use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.

What is the effect of Patroxta 12.5 Tablet PR on children?

Patroxta 12.5 Tablet PR should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Patroxta 12.5 Tablet PR. If your doctor has prescribed Patroxta 12.5 Tablet PR for your child and you are worried about these side effects, discuss it with your doctor.

I have been taking tamoxifen for breast cancer. Can I take Patroxta 12.5 Tablet PR with it?

No, you should not take Patroxta 12.5 Tablet PR if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Patroxta 12.5 Tablet PR. But Patroxta 12.5 Tablet PR may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.

Do I need to be careful while taking Patroxta 12.5 Tablet PR if I am a diabetic?

Yes, you need to be careful while taking this medicine if you are a diabetic. Patroxta 12.5 Tablet PR may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake Inhibitors (SSRIs)

References

Stahl SM, editor. Paroxetine. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
Paroxetine [EMC Label]. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2025. [Accessed 25 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2023. [Accessed 12 Dec. 2025] (online) Available from:
Paroxetine hydrochloride [Product Monograph]. East Windsor, NJ: Aurobindo Pharma Ltd.; 2025. [Accessed 11 Nov. 2025] (online). Available from:

User feedback

Patients taking Patroxta 12.5 Tablet PR

Once A Day

85%

Twice A Day

11%

Thrice A Day

Alternate Day

What are you using Patroxta Tablet PR for?

Depression

42%

Phobia

32%

Anxiety disorder

11%

Post traumatic stress disorder

11%

Others

How much was the improvement?

Excellent

41%

Poor

33%

Average

26%

What were the side-effects while using Patroxta 12.5 Tablet PR?

Fatigue

29%

Headache

14%

Nausea

14%

Diarrhea

14%

No Side Effect

How do you take Patroxta Tablet PR?

With food

71%

With or without food

14%

Empty stomach

14%

Please rate Patroxta 12.5 Tablet PR on price

Average

57%

Expensive

24%

Not Expensive

19%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Arinna Lifescience Pvt Ltd
Address: A – 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Patroxta 12.5 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Patroxta 12.5 Tablet PR

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Patroxta Tablet PR

Benefits of Patroxta Tablet PR

Side effects of Patroxta Tablet PR

How to use Patroxta Tablet PR

How Patroxta Tablet PR works

All substitutes for Patroxta 12.5 Tablet PR

Paxidep CR 12.5 Tablet

Depaxil CR 12.5 Tablet

Xet CR 12.5 Tablet

Paroxee CR 12.5 Tablet

Paradise XR 12.5 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tapentadol (Nasal Route)

Moclobemide (Oral Route)

Zolmitriptan (Nasal Route)

Tranylcypromine (Oral Route)

Selegiline (Oral Route)

Frequently asked questions

After how many days of taking Patroxta 12.5 Tablet PR will I start feeling better?

I feel that my symptoms have worsened after having started taking Patroxta 12.5 Tablet PR. Can I stop it on my own or do I need to consult the doctor?

Can Patroxta 12.5 Tablet PR affect my sex life?

What is the effect of Patroxta 12.5 Tablet PR on children?

I have been taking tamoxifen for breast cancer. Can I take Patroxta 12.5 Tablet PR with it?

Do I need to be careful while taking Patroxta 12.5 Tablet PR if I am a diabetic?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Patroxta 12.5 Tablet PR

What are you using Patroxta Tablet PR for?

How much was the improvement?

What were the side-effects while using Patroxta 12.5 Tablet PR?

How do you take Patroxta Tablet PR?

Please rate Patroxta 12.5 Tablet PR on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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