Pamorelin LA 22.5mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Pamorelin LA 22.5mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of uterus grows excessively and causes symptoms like pain, heavy or irregular periods), and central precocious puberty (very early puberty).

Pamorelin LA 22.5mg Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Hot flashes, weakness, increased sweating, fatigue,  back pain, and erectile dysfunction are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Pamorelin LA Injection

Benefits of Pamorelin LA Injection

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Pamorelin LA 22.5mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Endometriosis

Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Pamorelin LA 22.5mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.

In Precocious puberty (premature puberty)

When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Pamorelin LA 22.5mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered. Follow your doctor’s instructions carefully for the most benefit.

Side effects of Pamorelin LA Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pamorelin LA

  • Weakness
  • Increased sweating
  • Back pain
  • Paresthesia (tingling or pricking sensation)
  • Hot flashes
  • Erectile dysfunction

How to use Pamorelin LA Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pamorelin LA Injection works

Pamorelin LA 22.5mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Pamorelin LA 22.5mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pamorelin LA 22.5mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Pamorelin LA 22.5mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pamorelin LA 22.5mg Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Pamorelin LA 22.5mg Injection may cause side effects which could affect your ability to drive.
You may feel dizzy, tired or have problems with your eyesight such as blurred vision. This may affect your driving ability.
Kidney
CAUTION
Pamorelin LA 22.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pamorelin LA 22.5mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Pamorelin LA 22.5mg Injection should be used with caution in patients with liver disease. Dose adjustment of Pamorelin LA 22.5mg Injection may be needed. Please consult your doctor.

What if you forget to take Pamorelin LA Injection?

If you miss a dose of Pamorelin LA 22.5mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Pamorelin LA 22.5mg Injection helps in the treatment of locally advanced or metastatic prostate cancer.
  • It is given as an injection either under the skin or into a muscle.
  • It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
  • It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment. 
  • Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
  • Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
  • It may also be used to treat endometriosis and precocious puberty (premature puberty).

Fact Box

Chemical Class
Polypeptides
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
GNRH agonists/analogue

Patient concerns

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Hello doctor, my father is suffering from prostate cancer. He is on hormone treatment. Please tell me what is difference between leuprolide and pamorelin injection? Are both same?
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Both are different injections, and however effect is same
In which age does the girls have hairs in their undearms
Dr. Sunil Sekhri
Diabetology
During Puberty and the age range varies
arrow

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1410-11.
  2. Triptorelin pamoate. Slough, Berkshire: Ipsen Ltd.; 2010 [revised 17 Dec. 2016]. [Accessed 23 Jan. 2019] (online) Avaialble from:External Link
  3. Triptorelin pamoate. Martigny, Switzerland: Debio RP; 2000 [Accessed Jul. 2014]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Country of origin: India

Expires on or after: March, 2022

A licensed vendor partner from your nearest location will deliver Pamorelin LA 22.5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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