Palozest Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Palozest Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you the appropriate dose of the medicine depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections.

The most common side effects of taking this medicine include injection site pain, headache, and constipation. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Palozest Injection

Side effects of Palozest Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Palozest

Injection site pain
Constipation
Headache
Diarrhea
Dizziness

How to use Palozest Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Palozest Injection works

Palozest Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Palozest Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Palozest Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Palozest Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Palozest Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Palozest Injection is safe to use in patients with kidney disease. No dose adjustment of Palozest Injection is recommended.

Liver

SAFE IF PRESCRIBED

Palozest Injection is safe to use in patients with liver disease. No dose adjustment of Palozest Injection is recommended.

What if you forget to take Palozest Injection?

If you miss a dose of Palozest Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Palozest Injection

₹242/Injection

Palnox 0.25mg Injection

Glenmark Pharmaceuticals Ltd

₹165/injection

34% cheaper

Pasetron Injection

United Biotech Pvt Ltd

₹192/injection

23% cheaper

Palonoget 0.25mg Injection

GLS Pharma Ltd.

₹147/injection

41% cheaper

Wotron 0.25mg Injection

Dr Reddy's Laboratories Ltd

₹130/injection

48% cheaper

Themiset 0.25mg Injection

Themis Medicare Ltd

₹132/injection

47% cheaper

View all substitutes

Quick tips

You have been prescribed Palozest Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
Palozest Injection is given as an injection under the supervision of a doctor.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class

Isoquinoline and Quinuclidine Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

Interaction with drugs

Taking Palozest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Escitalopram Oxalate (Oral Route) Severe

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium... More

Imipramine (Oral Route) Severe

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines if required. Factors ... More

Venlafaxine (Oral Route) Severe

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium... More

Clomipramine (Oral Route) Severe

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium... More

Lithium carbonate (Oral Route) Severe

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines if required. Factors ... More

View all drug interactions

Patient concerns

What is side effect of primolut n

Dr. Megha Tuli

Obstetrics and Gynaecology

Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.

Vomiting, nausea neck pain backside

Dr. Vijay Verma

ENT

Neck pain may be due to nausea NAD vomiting Visit physician for the same

Vomiting nausea problem and fever

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

How quickly does Palozest Injection work?

Palozest Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

What are the side effects of Palozest Injection?

The most common side effects of Palozest Injection are constipation and headache. However, these are usually not bothersome and resolve on their own after sometime. If these persist or worry you, please consult your doctor.

Is Palozest Injection a steroid?

No, Palozest Injection is an antiemetic and not a steroid. Palozest Injection is a selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting caused after a surgery or due to cancer chemotherapy.

Does Palozest Injection work for seasickness?

No, Palozest Injection does not work for seasickness. This is because Palozest Injection has very little effect on the nausea associated with motion sickness.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
Palonosetron. Mulhuddart Dublin: Helsinn Birex Pharmaceuticals Ltd.; 2005 [revised 26 Apr. 2018]. [Accessed 28 Mar. 2019] (online) Available from:
Palonosetron. Bloomington, MN: MGI PHARMA, INC; 2006. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: