Imipramine

Information about Imipramine

Imipramine Uses

Imipramine is used in the treatment of depression, Anxiety, bed-wetting, obsessive-compulsive disorder, insomnia and neuropathic pain. It is used in patients intolerant of or unresponsive to other treatment options for depression.

How Imipramine works

Imipramine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects of Imipramine

Gastrointestinal disturbance, Nervousness, Sleep disorder, Tiredness
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Written By
Dr. Radhika Dua
MDS, BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Last updated
03 Dec 2024 | 05:02 AM (UTC)

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Expert advice for Imipramine

  • Imipramine is used for the treatment of depression and bedwetting in children.
  • The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
  • You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
  • Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. 
  • Do not drive or do anything that requires concentration until you know how this medicine affects you.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
  • It can take 2 to 3 weeks for Imipramine to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Imipramine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Imipramine, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Imipramine is very less.
  • It may be extremely dangerous in overdose. 

Frequently asked questions for Imipramine

Imipramine

Q. What is Imipramine used for?

Imipramine is mainly used to treat depression. It is also used to treat bed wetting in children older than 6 years of age. It works by restoring the chemical imbalance in the brain, thereby enhancing mood and behavior.

Q. What are the side effects of Imipramine?

Imipramine may cause side effects like increased heart rate, blurred vision, dryness in mouth, difficulty in urination, constipation and orthostatic hypotension (sudden decrease in blood pressure on standing). Consult your doctor if these side effects do not go away or worry you.

Q. Can I just stop taking Imipramine?

No, you must not stop taking Imipramine suddenly even if you are feeling good as it may worsen your condition. Continue taking Imipramine for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

Q. Can a pregnant woman take Imipramine?

No, pregnant women should avoid taking Imipramine, unless recommended by the doctor. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved. Taking this medicine during the last trimester of the pregnancy may cause symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors, and spasms in the newborn. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.

Q. Does Imipramine make you sleepy?

Yes, Imipramine may make you feel sleepy. Therefore, it is advised that you should not drive, use any heavy machinery or do any work that requires concentration while taking Imipramine. Also, refrain from taking alcohol if you are being treated with Imipramine as it will increase your drowsiness.

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