Palonosetron

Last updated 25 Nov 2025 | 09:34 AM (UTC)

Palonosetron Uses

Palonosetron is used to prevent vomiting and nausea.

How Palonosetron works

Palonosetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Common side effects of Palonosetron

Constipation, Headache, Diarrhea, Dizziness

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Medicine brands for Palonosetron

Instantino

Zuventus Healthcare Ltd

Intas Pharmaceuticals Ltd

₹90 to ₹369

2 variant(s)

Palozac

Ajanta Pharma Limited

₹106 to ₹106

1 variant(s)

Palzen

Dr Reddy's Laboratories Ltd

₹131 to ₹131

1 variant(s)

Palnox

Glenmark Pharmaceuticals Ltd

₹154 to ₹154

1 variant(s)

Palmocet

Miracalus Pharma Pvt Ltd

Einzig Pharmaceutical Pvt Ltd

₹70 to ₹93

2 variant(s)

Expert advice for Palonosetron

You have been prescribed Palonosetron for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
It comes in many different forms that do not need to be swallowed, such as a film that is placed on the tongue or as a dissolving pill.
It is fast-acting and starts working within 30 minutes.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
You have been prescribed Palonosetron for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
Unlike some other nausea medicines, the side effects for Palonosetron are relatively mild.
It comes in many different forms that do not need to be swallowed, such as a film that is placed on the tongue or as a dissolving pill.
It is fast-acting and starts working within 30 minutes.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Frequently asked questions for Palonosetron

Q. How quickly does Palonosetron work?

Palonosetron starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Palonosetron?

The most common side effects of Palonosetron are constipation and headache. However, these are usually not bothersome and resolve on their own after sometime. If these persist or worry you, please consult your doctor.

Q. When should you take Palonosetron?

Palonosetron can be taken with or without food with a glass full of water. The first dose of Palonosetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully.

Q. Is Palonosetron a steroid?

No, Palonosetron is an antiemetic and not a steroid. Palonosetron is a selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting caused after a surgery or due to cancer chemotherapy.

Q. Does Palonosetron work for seasickness?

No, Palonosetron does not work for seasickness. This is because Palonosetron has very little effect on the nausea associated with motion sickness.