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Paloron Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹63.6 MRP ₹70.3110% off 
 
 
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Paloron Injection image
Paloron Injection image

Product introduction

Paloron Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you the appropriate dose of the medicine depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections. 

The most common side effects of taking this medicine include injection site pain, headache, and constipation. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Paloron Injection

Benefits of Paloron Injection

Vomiting
Vomiting is the forceful expulsion of stomach contents, often triggered by infections, medical treatments like chemotherapy, or surgical procedures. Frequent vomiting can lead to dehydration, weakness, and a significant drop in energy levels. Paloron Injection helps prevent and control vomiting, especially in situations where it is difficult to manage, such as after chemotherapy or surgery. This leads to better comfort, helps maintain hydration and nutrition, and supports a smoother recovery process.
Nausea
Nausea is a queasy feeling in the stomach that often precedes vomiting and can make it difficult to eat, rest, or concentrate. It may occur due to motion sickness, medical treatments, or digestive issues. Paloron Injection helps ease this sensation and prevents it from getting worse, offering lasting relief. This allows individuals to feel more comfortable, eat better, and carry on with daily activities without constant discomfort or distress.

Side effects of Paloron Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paloron
  • Injection site pain
  • Constipation
  • Headache
  • Diarrhea
  • Dizziness

How to use Paloron Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Paloron Injection works

Paloron Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Quick tips

  • You have been prescribed Paloron Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • Paloron Injection is given as an injection under the supervision of a doctor.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Paloron Injection. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Paloron Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Paloron Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
Paloron Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Paloron Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Paloron Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Paloron with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Venlafaxine (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence. Your doctor may discontinue the medicines accordingly.
Severe

Clomipramine (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence. Your doctor may discontinue the medicines accordingly.
Severe

Escitalopram Oxalate (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence. Your doctor may discontinue the medicines accordingly.
Severe

Imipramine (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines if required. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Lithium carbonate (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may discontinue the medicines if required. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Paloron Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
The most common side effects of Paloron Injection are constipation and headache. However, these are usually not bothersome and resolve on their own after sometime. If these persist or worry you, please consult your doctor.
No, Paloron Injection is an antiemetic and not a steroid. Paloron Injection is a selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting caused after a surgery or due to cancer chemotherapy.
No, Paloron Injection does not work for seasickness. This is because Paloron Injection has very little effect on the nausea associated with motion sickness.

Fact Box

Chemical Class

Isoquinoline derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Palonosetron. Mulhuddart Dublin: Helsinn Birex Pharmaceuticals Ltd.; 2005 [revised 26 Apr. 2018]. [Accessed 28 Mar. 2019] (online) Available from:
  3. Palonosetron. Bloomington, MN: MGI PHARMA, INC; 2006. [Accessed 28 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Einzig Pharmaceutical Pvt Ltd
Address: C-1/38,3rd Floor, Old Village Jasola Ext., Jasola, New Delhi – 110025

Vendor Details

Country of origin: India
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