Paliris LA 150mg Injection
Prescription Required
Product introduction
Paliris LA 150mg Injection is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It helps control symptoms like hallucinations, mood swings, and disorganized thinking.
Paliris LA 150mg Injection is given under the supervision of a doctor. Get the injection regularly and at the same time each day to help maintain a consistent level of medicine in the body. This medication should not be stopped suddenly without talking to your doctor, as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness.
Some common side effects of this medicine include injection site reactions (pain, swelling, redness), tremors, anxiety, and weight gain. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
You should be cautious if you are using this medicine, as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Uses of Paliris Injection
Benefits of Paliris Injection
In Mania
Mania means extremely excited or elevated mood. Paliris LA 150mg Injection helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Paliris LA 150mg Injection will ensure that you have a better social life and are able to do daily activities more comfortably.
Side effects of Paliris Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paliris
- Abnormal involuntary movements
- Dizziness
- Injection site reactions (pain, swelling, redness)
- Nystagmus (involuntary eye movement)
- Sleepiness
- Cogwheel rigidity
- Tremors
- Fast heart rate
How to use Paliris Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Paliris Injection works
Paliris LA 150mg Injection is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts, and behavior.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Paliris LA 150mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Paliris LA 150mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Paliris LA 150mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Paliris LA 150mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Paliris LA 150mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Paliris LA 150mg Injection may be needed. Please consult your doctor.
Use of Paliris LA 150mg Injection is not recommended in patients with end-stage kidney disease.
Use of Paliris LA 150mg Injection is not recommended in patients with end-stage kidney disease.
Liver
CAUTION
Paliris LA 150mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Paliris LA 150mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Paliris LA 150mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Paliris LA 150mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Paliris Injection?
If you miss a dose of Paliris LA 150mg Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Paliris LA 150mg Injection
₹2668/Injection
Invega Sustenna 150mg Injection
Janssen Pharmaceuticals
₹6180/injection
113% costlier
Paliris LA 150mg Injection
Sun Pharmaceutical Industries Ltd
₹3184/injection
10% costlier
Quick tips
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Paliris LA 150mg Injection can cause dizziness and sleepiness.
- It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
- Monitor your blood sugar regularly as Paliris LA 150mg Injection can affect blood sugar levels.
- Do not stop taking Paliris LA 150mg Injection without talking to your doctor first, as it may cause a worsening of symptoms.
Fact Box
Chemical Class
Benzisoxazole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Atypical Antipsychotics
Interaction with drugs
Taking Paliris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Haloperidol with Paliperidone.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Paliperidone.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Amiodarone with Paliperidone.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Escitalopram Oxalate with Paliperidone.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Iloperidone with Paliperidone.
Concomitant use may affect heart rhythm and may be fatal.
Patient concerns
FAQs
Is paliperidone the same as risperidone?
Paliperidone gets converted to risperidone in the body and thus exerts similar actions
Is Paliris LA 150mg Injection a narcotic?
No, Paliris LA 150mg Injection is not a narcotic
Is Paliris LA 150mg Injection an atypical antipsychotic?
Yes, Paliris LA 150mg Injection is an atypical antipsychotic
How is Paliris LA 150mg Injection metabolized?
Paliris LA 150mg Injection is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes
Does Paliris LA 150mg Injection cause weight gain?
Yes, Paliris LA 150mg Injection is known to cause weight gain
Does Paliris LA 150mg Injection cause erectile dysfunction?
Paliris LA 150mg Injection may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use
How long does Paliris LA 150mg Injection stay in your system?
Oral Paliris LA 150mg Injection may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Paliperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 503-508.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1047-48.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paliperidone. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
- Paliperidone [Patient Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2025. [Accessed 16 Mar. 2025] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
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DISCONTINUED
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