Paliris 3 Tablet ER is a prescription medicine used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania.

Paliris 3 Tablet ER may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness.

Some common side effects of this medicine includes nystagmus (involuntary eye movement) and tremor. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

You should be cautious if you are using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Uses of Paliris Tablet ER

Benefits of Paliris Tablet ER

In Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Paliris 3 Tablet ER helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

In Mania

Mania means extremely excited or elevated mood. Paliris 3 Tablet ER helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Paliris 3 Tablet ER will ensure that you have a better social life and are able to do daily activities more comfortably.

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Side effects of Paliris Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Paliris

Abnormal involuntary movements
Dizziness
Nystagmus (involuntary eye movement)
Sleepiness
Tremor

How to use Paliris Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Paliris 3 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.

How Paliris Tablet ER works

Paliris 3 Tablet ER is an atypical antipsychotic. It works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

Safety Advice

Alcohol

UNSAFE

Paliris 3 Tablet ER may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Paliris 3 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

Paliris 3 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Paliris 3 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Paliris 3 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Paliris 3 Tablet ER may be needed. Please consult your doctor.
Use of Paliris 3 Tablet ER is not recommended in patients with end-stage kidney disease.

Liver

CAUTION

Paliris 3 Tablet ER should be used with caution in patients with severe liver disease. Dose adjustment of Paliris 3 Tablet ER may be needed. Please consult your doctor.
Limited information is available on the use of Paliris 3 Tablet ER in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Paliris 3 Tablet ER

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Palido-OD 3 Tablet ER

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₹7.13/Tablet ER

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Palip XR 3 Tablet

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Quick Tips

Take it in the morning, preferably at the same time every day.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Paliris 3 Tablet ER can cause dizziness and sleepiness.
It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
Monitor your blood sugar regularly as Paliris 3 Tablet ER can affect blood sugar levels.
Do not stop taking Paliris 3 Tablet ER without talking to your doctor first as it may cause a worsening of symptoms.

Fact Box

Chemical Class

Benzisoxazole Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Interaction with Drugs

Taking Paliris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Clotrimazole

Brand(s): Clowil, Odis, Kamestin

LIFE-THREATENING

Fluconazole

Brand(s): Fungis, EF Z, Rocflu

LIFE-THREATENING

Itraconazole

Brand(s): Indizole, Itracip, Itraspan

LIFE-THREATENING

Miconazole

Brand(s): Canticid

LIFE-THREATENING

View all interactions

Patient Concerns

How to treat erectile dysfunction with schizophrenia

Dr. Deepak Kumar Soni

Ayurveda

https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months

I am suffering from mania .what should i do.

Dr. Vikas Sharma

Neurology

Show. To psychiatric

Suffering from Depression and Mania, what should be done

Dr. Jyoti Kapoor Madan

Psychiatry

Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.

I an suffering from mania what should i do.

Dr. Jyoti Kapoor Madan

Psychiatry

Mania is a component of Bipolar Affective Disorder. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.

Having Depression and mania along with asomnia since last two years. Taking sodium valproate. 1500 mg OD. Little improved only.

Dr. Jyoti Kapoor Madan

Psychiatry

Response to medicines depends on- 1. Diagnosis 2. Adequate dose of medicines 3. Adequate duration of treatment 4. Regular Medicines 5. Individual factors like patient's metabolism, other medical conditions etc. Resistance to medicines can be because of following factors- 1. Diagnostic confusion 2. Irregular treatment or lack of proper follow up with treating doctor 3. Inadequate dose of medicines 4. Pharmacodynamics/ pharmacokinetics 5. Internal biological resistance For Treatment Resistant Conditions, adjunctive measures like changing treatment goals, psychotherapy and ECTs can be tried

suffering from schizophrenia plz help

Dr. Jyoti Kapoor Madan

Psychiatry

Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance.

Do you have any questions related to Paliris 3 Tablet ER ?

CONSULT A DOCTOR ONLINE

User Feedback

Patients taking Paliris 3 Tablet ER

Once A Day

89%

Twice A Day

11%

What are you using Paliris Tablet ER for?

Schizophrenia

80%

Mania

20%

How much was the improvement?

Poor

56%

Excellent

33%

Average

11%

What were the side-effects while using Paliris 3 Tablet ER?

Insomnia (dif*

50%

Dizziness

50%

*Insomnia (difficulty in sleeping)

How do you take Paliris Tablet ER?

With food

100%

Please rate Paliris 3 Tablet ER on price

Expensive

100%

FAQs

Q. Is paliperidone the same as risperidone?

Paliperidone gets converted to risperidone in the body and thus exerts similar actions

Q. Is Paliris 3 Tablet ER a narcotic?

No, Paliris 3 Tablet ER is not a narcotic

Q. Is Paliris 3 Tablet ER an atypical antipsychotic?

Yes, Paliris 3 Tablet ER is an atypical antipsychotic

Q. How is Paliris 3 Tablet ER metabolized?

Paliris 3 Tablet ER is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes

Q. Does Paliris 3 Tablet ER cause weight gain?

Yes, Paliris 3 Tablet ER is known to cause weight gain

Q. Does Paliris 3 Tablet ER cause erectile dysfunction?

Paliris 3 Tablet ER may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use

Q. How long does Paliris 3 Tablet ER stay in your system?

Oral Paliris 3 Tablet ER may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Paliperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 503-508.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1047-48.
Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2007 [revised 13 Sep. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Paliperidone. Vacaville, California: ALZA Corporation; 2006. [Accessed 25 Mar 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paliperidone. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Drugs.com. Paliperidone. [Accessed 25 Mar. 2019]. (online) Available from:
Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 13 Sep. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

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