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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Oxoplan 50mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Oxoplan 50mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Oxoplan 50mg Injection is given as an injection into vein by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.

Uses of Oxoplan Injection

Side effects of Oxoplan Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Oxoplan

  • Nausea
  • Fatigue
  • Anemia (low number of red blood cells)
  • Vomiting
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Low blood platelets
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Fatigue
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Anemia (low number of red blood cells)
    Making some simple lifestyle changes can raise your red blood cell count. Reduce the amount of alcohol you drink, eat a well-balanced healthy diet and take regular exercise. Physical activities make your body need more oxygen and this stimulates the production of red blood cells. There are some vitamins which are important such as vitamin B-12, vitamin B-9, vitamin C and Vitamin A. Also, some minerals such as iron (especially) and copper. Aim for foods which contain higher quantities of these vitamins and minerals or ask your doctor for supplements. Make sure to consult your doctor for complete evaluation and treatment of anemia.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Decreased white blood cell count (neutrophils)
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.
  • Coping with Low blood platelets
    You will need a blood test to find out if your blood platelet level is low. If this medicine is causing your platelet levels to drop, your doctor may suggest an alternative medicine. There are also medicines that can boost your blood platelet level. Consider asking your doctor about this. A low platelet count can put you at risk for bleeding. Try to be careful when doing activities that might cause an injury or a cut as it may take longer to stop bleeding.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.

How to use Oxoplan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Oxoplan Injection works

Oxoplan 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oxoplan 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Oxoplan 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Oxoplan 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Oxoplan 50mg Injection may cause side effects which could affect your ability to drive.
Oxaliplatin_name$ treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
Kidney
CAUTION
Oxoplan 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Oxoplan 50mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Oxoplan 50mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Oxoplan 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Oxoplan 50mg Injection may be needed. Please consult your doctor.

What if you forget to take Oxoplan Injection?

If you miss a dose of Oxoplan 50mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Oxoplan 50mg Injection
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Oxa 50mg Injection
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Dacotin 50 Injection
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Quick Tips

  • Oxoplan 50mg Injection is given as an injection into veins under the supervision of a doctor.

Fact Box

Chemical Class
Platinum Analogs
Habit Forming
No

Patient Concerns

arrow
Is ulcers curable G2 stage of cancer in rectum area
Dr. Pawan Rawal
Gastroenterology
Needs evaluation Please meet a Gastro surgeon
My dad is suffering from colon cancer How to get rid of it
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Surgery is main stay of treatment, which should be followed by chemotherapy.
arrow
Do you have any questions related to Oxoplan 50mg Injection ?

FAQs

Q. Is Oxoplan highly emetogenic, ototoxic (hearing loss), cause hair loss, infertility, diarrhea, neuropathy, cold sensitivity?

Oxoplan is highly emetogenic, can cause hair loss, temporary infertility, diarrhea, neuropathy, cold sensitivity. Oxoplan is not ototoxic

Q. Is Oxoplan a vesicant, chemo drug, alkylating agent?

Oxoplan is a vesicant, chemotherapeutic drug. Oxoplan is not an alkylating agent it is a platinum containing antineoplastic agent

Q. How is Oxoplan administered?

Oxoplan is administered as intravenous infusion or bolus injection.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
  4. Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from:External Link
  5. Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Country of Origin: India
A licensed vendor partner from your nearest location will deliver Oxoplan 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹1123.79
1 ml in 1 vial
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