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Oxaliplatin is used in the treatment of cancer of colon and rectum

How it works

Oxaliplatin works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Nausea, Fatigue, Anemia, Vomiting, Diarrhoea, Decreased white blood cell count (neutrophils), Reduced blood platelets, Increased liver enzymes, Peripheral sensory neuropathy, Stomatitis (Inflammation of the mouth)

Available Medicine

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Expert advice

  • Do not start oxaliplatin if your blood counts are too low or have weakness, numbness, disturbances of feeling or taste after taking oxaliplatin treatment, if you are taking 5-fluorouracil.
  • Take precautions as oxaliplatin may reduce the ability of your body fight infections.
  • Avoid situations that may put you at risk of bleeding as oxaliplatin can reduce clot forming cells in your body.
  • Take necessary precaution as oxaliplatin can make you more sensitive to cold, which can cause numbness, tingling, and muscle spasms.
  • Do not drive or operate machinery as oxaliplatin can cause nausea, vomiting, dizziness, and other neurologic symptoms.

Frequently asked questions



Is oxaliplatin highly emetogenic, ototoxic (hearing loss), cause hair loss, infertility, diarrhea, neuropathy, cold sensitivity?
Oxaliplatin is highly emetogenic, can cause hair loss, temporary infertility, diarrhea, neuropathy, cold sensitivity. Oxaliplatin is not ototoxic


Is oxaliplatin a vesicant, chemo drug, alkylating agent?
Oxaliplatin is a vesicant, chemotherapeutic drug. Oxaliplatin is not an alkylating agent it is a platinum containing antineoplastic agent


How is oxaliplatin administered?
Oxaliplatin is administered as intravenous infusion or bolus injection.

Content on this page was last updated on 26 April, 2017, by Dr. Varun Gupta (MD Pharmacology)