Oxakrish 2mg/ml Injection
Prescription Required
Product introduction
Oxakrish 2mg/ml Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.
Oxakrish 2mg/ml Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.
Uses of Oxakrish Injection
Benefits of Oxakrish Injection
In Cancer of colon and rectum
Oxakrish 2mg/ml Injection is used in the treatment of colon and rectal cancer to help slow disease progression and reduce the risk of the cancer returning. It is often part of combination therapy to improve treatment effectiveness and support long-term outcomes.
Side effects of Oxakrish Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oxakrish
- Skin disorder
- Decreased appetite
- Infection
- Taste change
- Edema (swelling)
- Anemia (low number of red blood cells)
- Decreased white blood cell count (neutrophils)
- Low blood platelets
- Headache
- Breathlessness
- Peripheral sensory neuropathy
- Inflammation of the nose
- Pain
- Increased transaminase level in blood
- Increased alkaline phosphatase level in blood
- Abdominal pain
- Injection site reaction
- Weight gain
- Conjunctivitis
- Fever
- Nosebleeds
- Hair loss
- Constipation
- Lacrimation disorder
- Allergic reaction
- Fatigue
- Nausea
- Vomiting
- Diarrhea
- Stomatitis (Inflammation of the mouth)
How to use Oxakrish Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Oxakrish Injection works
Oxakrish 2mg/ml Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oxakrish 2mg/ml Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Oxakrish 2mg/ml Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Oxakrish 2mg/ml Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Oxakrish 2mg/ml Injection may cause side effects which could affect your ability to drive.
Oxakrish 2mg/ml Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
Oxakrish 2mg/ml Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
Kidney
CAUTION
Oxakrish 2mg/ml Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Oxakrish 2mg/ml Injection may be needed. Please consult your doctor.
Limited information is available on the use of Oxakrish 2mg/ml Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Limited information is available on the use of Oxakrish 2mg/ml Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Oxakrish 2mg/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Oxakrish 2mg/ml Injection may be needed. Please consult your doctor.
What if you forget to take Oxakrish Injection?
If you miss a dose of Oxakrish 2mg/ml Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Oxakrish 2mg/ml Injection
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Quick tips
- Oxakrish 2mg/ml Injection is given as an injection into veins under the supervision of a doctor.
- Oxakrish 2mg/ml Injection is given as an injection into veins under the supervision of a doctor.
Fact Box
Chemical Class
Platinum Analogs
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Platinum-Based Alkylating Agents
Interaction with drugs
Taking Oxakrish with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Oxaliplatin from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marr
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Concurrent use may cause a decrease in the ability of the bone marrow to pr
Do not consume Oxaliplatin with Domperidone.
Concomitant use may affect heart rhythm.
Do not consume Oxaliplatin from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone
Do not consume Oxaliplatin from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marr
Patient concerns
FAQs
What is Oxakrish 2mg/ml Injection used for?
Oxakrish 2mg/ml Injection is a chemotherapy medicine used to treat colon and colorectal cancer. It is often combined with other anti-cancer medications to stop or slow the growth of cancer cells, especially after surgery or in advanced cancer stages
Can Oxakrish 2mg/ml Injection cause allergic reactions?
Yes, Oxakrish 2mg/ml Injection may cause severe allergic reactions, including rash, shortness of breath, chest tightness, dizziness, and in rare cases, anaphylaxis. These reactions can happen suddenly, even if you have taken the medicine before. Immediate medical attention is required in these cases.
Why does Oxakrish 2mg/ml Injection cause cold sensitivity?
One of the unique effects of Oxakrish 2mg/ml Injection is temporary sensitivity to cold, which can cause throat tightness, difficulty swallowing, and tingling sensations. Avoid cold drinks, foods, or exposure to cold air during and after treatment for a few days.
Who should not receive Oxakrish 2mg/ml Injection?
People who are allergic to oxaliplatin or other platinum-based drugs should not take Oxakrish 2mg/ml Injection. It is also not suitable for patients with severe kidney problems or those who have previously had serious reactions to chemotherapy.
What should I do if I experience numbness or tingling in my hands and feet during Oxakrish 2mg/ml Injection therapy?
During Oxakrish 2mg/ml Injection therapy, numbness or tingling in hands and feet are signs of oxaliplatin-induced neuropathy. Inform your doctor immediately if the symptoms worsen or affect your daily activities. In some cases, your doctor may reduce the Oxakrish 2mg/ml Injection dose and may stop the treatment to prevent long-term damage.
How long does treatment with Oxakrish 2mg/ml Injection last?
For early-stage colon cancer, Oxakrish 2mg/ml Injection is usually given for about 6 months (12 cycles). For advanced cancer, treatment may continue until the cancer stops responding or side effects become too severe.
What precautions should be taken during Oxakrish 2mg/ml Injection treatment?
During Oxakrish 2mg/ml Injection treatment, avoid cold foods and drinks, wear gloves in cold weather, and stay away from people who are sick, because your immune system might be weaker. Always report symptoms like difficulty breathing, extreme fatigue, or fever to your doctor immediately.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
- Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
- Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Murli Krishna Pharma Pvt Ltd
Address: D 98, Pune Nagar Road, Ranjangaon, Pune - 412220 (MIDC Taluka Shirur)
Country of origin: India
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₹2186
Inclusive of all taxes
MRP₹2346 7% OFF
25.0 ml in 1 vial
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