Ortholate Suspension

Erythromycin (100mg)

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Ortholate Suspension is an antibiotic medicine that helps treat bacterial infections of the eye, ear, nose, throat, lungs, teeth, skin, and urinary tract. Also given as an alternative therapy to penicillin allergy, Ortholate Suspension may help treat certain specific infections such as pertussis (whooping cough) and diphtheria.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 22 Apr 2026 | 09:31 PM (IST)

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General Information

Contains

Erythromycin (100mg)

Marketer

Oyster Labs Ltd

Storage

Store below 30°C

The content is shown in English

Your child’s medicine at a glance

Prefer giving Ortholate Suspension on an empty stomach (either 1 hour before or 2 hours after food) as that will enhance the medicine’s absorption. However, if stomach upset occurs, give it with a small amount of food. Ortholate Suspension is usually given four times a day. Since the dose depends upon the type of infection, its severity, and your child’s age and body weight, make sure to stick to the dose, time, and way prescribed by the doctor.

The usual duration of the treatment is 5 to 10 days, depending upon infection severity and how well your child responds to the treatment. Ensure that your child completes the full prescribed course of the medicine as stopping it abruptly may worsen your child’s condition or increase the risk of reinfection. In case your child vomits within 30 minutes of taking this medicine, help your child calm down and then give the same dose again.

This medicine may have some mild side effects. including nausea, vomiting, diarrhea, and stomach pain. These side effects should recede on their own within a few days. However, in case these effects persist or become bothersome for your child, consult your child’s doctor without any delay.

Inform your child’s doctor if your child has a history of allergies, heart problems, liver impairment, or kidney malfunction. Knowing the child’s medical history is critical for dose alterations and for planning your child’s overall treatment.

Uses of Ortholate Suspension in children

Benefits of Ortholate Suspension for your child

Treatment of Bacterial infections
Ortholate Suspension is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs and skin. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Treatment of Pertussis
Pertussis is a highly contagious respiratory tract infection that can be life-threatening for infants. It is marked by a severe hacking cough followed by a high-pitched intake of breath that sounds like whoop. It is easily preventable by vaccine, but Ortholate Suspension is given if a child develops the infection.

Treatment of Diphtheria
It is a serious infection of the nose and throat in which a layer of thick, grey matter covers the back of the throat, making breathing hard. It is easily preventable by vaccine, but Ortholate Suspension is given if a child develops the infection.

Side effects of Ortholate Suspension in children

Ortholate Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Ortholate

Nausea
Vomiting
Abdominal pain
Diarrhea
Decreased appetite

How can I give Ortholate Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ortholate Suspension is to be taken on an empty stomach.

How Ortholate Suspension works

Ortholate Suspension is an antibiotic. It works by interfering with the synthesis of essential proteins required by bacteria to perform important functions. By doing so, it stops the infection-causing bacteria from growing further and prevents the infection from spreading.

Quick tips

Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
Do not give Ortholate Suspension to treat viral infections as it will be ineffective.
Give Ortholate Suspension only for the current infection. Never save medicine for future illnesses.
Stop Ortholate Suspension and call the doctor right away if your child develops an itchy rash, facial swelling, or breathing difficulty soon after the intake.
Give Ortholate Suspension only when prescribed by the doctor. Never share your child's medicine with anyone else as it can harm.

Safety advice

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Ortholate Suspension in patients with kidney disease. Please consult your doctor.
However, inform your doctor if you have any kidney disease as the use of this medicine may affect hearing in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Ortholate Suspension in patients with liver disease.

Interaction with drugs

Taking Ortholate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Erythromycin.

Life-threatening

Simvastatin (Oral Route)

Do not consume Simvastatin with Erythromycin. If Erythromycin is essential, your doctor may temporarily stop Simvastatin. Erythromycin may raise blood levels of Simvastatin.

Life-threatening

Lovastatin (Oral Route)

Do not consume Lovastatin with Erythromycin. If Erythromycin is essential, your doctor may temporarily stop Lovastatin. Erythromycin may raise blood levels of Lovastatin.

Life-threatening

Disopyramide (Oral Route)

Do not consume Disopyramide with Erythromycin. If concurrent use is essential, please consult your doctor. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Carbamazepine (Oral Route)

Do not consume Carbamazepine with Erythromycin. If concurrent use is essential, watch out for symptoms such as impaired coordination, double vision, dizziness or confusion and consult your doctor if you experience them. Erythromycin may raise blood levels of Carbamazepine.

Frequently asked questions

What if I give an overdose of Ortholate Suspension by mistake?

Though an extra dose of Ortholate Suspension does not usually cause any harm, you must consult a doctor immediately if you feel you have given too much of it to your child. Never forget that overdose can increase the risk of unwanted side effects and may even worsen your child’s condition. So, stay vigilant and adhere to the prescribed dose.

What are the serious side effects of Ortholate Suspension?

Ortholate Suspension may rarely cause some serious side effects such as severe gastrointestinal infections (superinfection), severe allergic reactions, liver dysfunction, blood infections, and heart conduction abnormalities like QT prolongation due to arrhythmia. Always consult your child’s doctor for help in such a situation.

Can other medicines be given at the same time as Ortholate Suspension?

Ortholate Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Ortholate Suspension. Also, check with your child’s doctor before giving any medicine to your child.

Is it safe to give Ortholate Suspension if my child has low potassium levels in blood?

Avoid giving Ortholate Suspension if your child has low potassium levels as it can lead to conduction abnormalities of the heart such as arrhythmias (QT prolongation).

Can I get my child vaccinated while on treatment with Ortholate Suspension ?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Which lab tests should my child undergo while taking Ortholate Suspension for the long term?

Your child’s doctor may advise you to track your child’s ECG and liver functioning periodically as that will help to keep a check on your child’s condition.

My child is having a sore throat and ear infection. Can I give antibiotics?

No. Sore throats, runny nose, cough, pain, or discharge from the ear are almost always caused by viruses. As per statistics, more than 80% of sore throats and ear infections are caused by a virus. Since antibiotics should not be given for viral infections, it will be best if you consult your child’s doctor to seek guidance.

Fact Box

Chemical Class

Macrolides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1327-28.
Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 799-800.
University of Michigan: C.S. Mott Children’s Hospital. Erythromycin. [Accessed 14 Jan. 2021] (online) Available from:
Erythromycin. Ahmedabad, Gujarat: Swiss Pharma Pvt. Ltd.; 2020. [Accessed 22 Apr. 2026] (online). Available from:

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