Ondef 2mg Drop
Prescription Required
Product introduction
Ondef 2mg Drop is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
Ondef 2mg Drop may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double the dose if it is already time for the next dose.
Ondef 2mg Drop may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.
Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.
Side effects of Ondef Drop
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ondef
- Headache
- Constipation
- Diarrhea
- Fatigue
How to use Ondef Drop
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Ondef 2mg Drop may be taken with or without food, but it is better to take it at a fixed time.
How Ondef Drop works
During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Ondef 2mg Drop just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Ondef 2mg Drop. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Ondef 2mg Drop during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ondef 2mg Drop during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Ondef 2mg Drop alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Ondef 2mg Drop is safe to use in patients with kidney disease. No dose adjustment of Ondef 2mg Drop is recommended.
Liver
CAUTION
Ondef 2mg Drop should be used with caution in patients with liver disease. Dose adjustment of Ondef 2mg Drop may be needed. Please consult your doctor.
What if you forget to take Ondef Drop?
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
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Quick tips
- Ondef 2mg Drop effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
- It is fast-acting and starts working within 30 minutes.
- Practice self-care measures:
- Give plenty of fluids to your child to avoid dehydration
- Avoid giving fried and spicy food or heavy meals to your child.
- Ensure that your child eats slowly and in small proportions.
Fact Box
Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists
Interaction with drugs
Taking Ondef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Ondansetron.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Hydroxyzine with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Efavirenz with Ondansetron.
Patient concerns
FAQs
What is Ondef 2mg Drop used for?
Ondef 2mg Drop is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Ondef 2mg Drop to your child to prevent vomiting post-procedure. Apart from this, Ondef 2mg Drop is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Ondef 2mg Drop to your child for a few days. Stick to the dose for best results.
What if my child takes too much Ondef 2mg Drop?
Ondef 2mg Drop is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Ondef 2mg Drop can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
How should Ondef 2mg Drop be stored?
Ondef 2mg Drop should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
What all medicines should my child avoid while taking Ondef 2mg Drop?
Usually, it is advised not to give Ondef 2mg Drop along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.
In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
My child is having a migraine and is on medication. Can I give Ondef 2mg Drop along with it?
Avoid combining Ondef 2mg Drop with such medicines because concomitant use of Ondef 2mg Drop with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
- Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
- Ondansetron [Package leaflet: Information for the user]. Harefield, UK: Norgine Pharmaceuticals Limited; 2023. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Sristi Pharmaceuticals
Address: Plot no-315, Industrial Area Phase-2, Panchkula - 134113, Haryana , India
Country of origin: India
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