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MDS, BDS
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MBA, MD Pharmacology
Last updated
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Ondafit Syrup

Prescription Required

Product introduction

Ondafit Syrup is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.

Ondafit Syrup may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double the dose if it is already time for the next dose.

Ondafit Syrup may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.

Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.


Uses of Ondafit Syrup


Side effects of Ondafit Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondafit

  • Headache
  • Constipation
  • Diarrhea
  • Fatigue

How to use Ondafit Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ondafit Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Ondafit Syrup works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Ondafit Syrup just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Ondafit Syrup. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Ondafit Syrup during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ondafit Syrup during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Ondafit Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Ondafit Syrup is safe to use in patients with kidney disease. No dose adjustment of Ondafit Syrup is recommended.
Liver
CAUTION
Ondafit Syrup should be used with caution in patients with liver disease. Dose adjustment of Ondafit Syrup may be needed. Please consult your doctor.

What if you forget to take Ondafit Syrup?

Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Ondafit Syrup
₹35.6/Syrup
Nusetron 2mg Syrup
Abia Pharmaceuticals Pvt. Ltd.
₹35/syrup
5% cheaper
Ondrea 2mg Syrup
Cinerea Biotech Pvt Ltd
₹36.3/syrup
1% cheaper
Onfresh 2mg Syrup
Alcott Healthcare Pvt Ltd
₹36.5/syrup
1% cheaper
Lecton 2mg Syrup
Gracia Life Science India Pvt Ltd
₹30/syrup
18% cheaper
Deron 2mg Syrup
LifeCare Formulation Pvt Ltd
₹32.31/syrup
12% cheaper

Quick tips

  • Ondafit Syrup effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
  • It is fast-acting and starts working within 30 minutes.
  • Practice self-care measures:
    1. Give plenty of fluids to your child to avoid dehydration
    2. Avoid giving fried and spicy food or heavy meals to your child. 
    3. Ensure that your child eats slowly and in small proportions.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists

Interaction with drugs

Taking Ondafit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal. Do not consume Fluconazole with Ondansetron.
Concomitant use may affect heart rhythm and can be fatal. Do not consume Domperidone with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Hydroxyzine with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Voriconazole with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Efavirenz with Ondansetron.

Patient concerns

arrow
What is side effect of primolut n
Dr. Megha Tuli
Obstetrics and Gynaecology
Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
Vomiting, nausea neck pain backside
Dr. Vijay Verma
ENT
Neck pain may be due to nausea NAD vomiting Visit physician for the same
arrow

FAQs

What is Ondafit Syrup used for?

Ondafit Syrup is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Ondafit Syrup to your child to prevent vomiting post-procedure. Apart from this, Ondafit Syrup is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Ondafit Syrup to your child for a few days. Stick to the dose for best results.

What if my child takes too much Ondafit Syrup?

Ondafit Syrup is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Ondafit Syrup can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.

How should Ondafit Syrup be stored?

Ondafit Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.

What all medicines should my child avoid while taking Ondafit Syrup?

Usually, it is advised not to give Ondafit Syrup along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.

In what conditions do I need to call my child’s doctor right away?

Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.

My child is having a migraine and is on medication. Can I give Ondafit Syrup along with it?

Avoid combining Ondafit Syrup with such medicines because concomitant use of Ondafit Syrup with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:External Link
  2. Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:External Link
  3. Ondansetron [Package leaflet: Information for the user]. Harefield, UK: Norgine Pharmaceuticals Limited; 2023. [Accessed 25 Jul. 2024] (online) Available from: External Link

Marketer details

Name: Algen Healthcare Limited
Address: 134/2, Village Khara Kheri, Sadhaura Road, Kala Amb, Distt. Sirmour H.P 173030
Country of origin: India

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