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Ondacure Injection

Ondansetron (2mg/ml)
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Ondacure Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused by any surgery, cancer drug therapy, or radiotherapy.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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2 ml Injection
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General Information

The content is shown in English
Ondacure Injection image
Ondacure Injection image
Ondacure Injection image

Product introduction

Ondacure Injection is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you the appropriate dose depending on what you are taking it for. You must keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections.


The most common side effects of taking this medicine include injection site pain, headache, and constipation. These symptoms should disappear when you stop taking the medicine. But if these side effects bother you or do not go away, consult your doctor, who may be able to suggest ways of preventing or reducing them.


Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect or be affected by this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Uses of Ondacure Injection

Benefits of Ondacure Injection

Nausea
Ondacure Injection helps in relieving nausea, making it easier to go about daily activities without discomfort. Whether caused by travel, certain foods, or other conditions, it provides relief and helps improve overall well-being.
Vomiting
Ondacure Injection is useful in managing vomiting, allowing the body to retain essential fluids and nutrients. Reducing the frequency of vomiting helps prevent weakness and dehydration, promoting faster recovery and comfort.

Side effects of Ondacure Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ondacure
  • Diarrhea
  • Fatigue
  • Headache
  • Injection site pain
  • Constipation

How to use Ondacure Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Ondacure Injection works

Ondacure Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Quick tips

  • Ondacure Injection is given as an injection into the veins or as a drip under the supervision of a doctor.
  • Avoid heavy meals and try eating small, nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
  • It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Ondacure Injection does not usually cause any harmful side effects.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Ondacure Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Ondacure Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

SAFE
Ondacure Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Ondacure Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Ondacure Injection in patients with liver disease.

Interaction with drugs

Taking Ondacure with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Ondansetron.
Life-threatening

Voriconazole (Oral Route)

Do not consume Voriconazole with Ondansetron.
Life-threatening

Fluconazole (Oral Route)

Do not consume Fluconazole with Ondansetron.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Ondansetron.
Life-threatening

Efavirenz (Oral Route)

Do not consume Efavirenz with Ondansetron.

Frequently asked questions

Ondacure Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
The most common side effects of Ondacure Injection are constipation, diarrhea, fatigue, and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.
No, Ondacure Injection is an antiemetic and not a steroid. Ondacure Injection is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting, which are commonly observed after surgery or due to cancer chemotherapy.
No, Ondacure Injection does not work for seasickness. This is because Ondacure Injection has very little effect on the nausea associated with motion sickness.

Fact Box

Chemical Class

Carbazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  5. Ondansetron [Product information]. Eatontown, NJ: WEST-WARD; 2024 [Accessed 02 Apr. 2025] (online) Available from
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aurista Pharma Pvt Ltd.
Address: ROORKEE HARIDWAR, Uttarakhand(INDIA) 247667

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ondacure Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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