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Normictal 400mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 17 Dec 2025 | 04:35 PM (IST)
Normictal 400mg Tablet is a prescription medicine used to treat epilepsy (seizures). It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.
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Zefretol 400 Tablet
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Normictal 400mg Tablet
Normictal 400mg Tablet
strip of 10 tablets
₹119
₹131.25
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Same composition
Zefretol 400 Tablet
Zefretol 400 Tablet
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₹232
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General Information

The content is shown in English
Normictal 400mg Tablet image
Normictal 400mg Tablet image

Product introduction

Normictal 400mg Tablet may be taken with or without food, preferably at the same time, each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it abruptly without discussing it with your doctor, as it may increase seizure frequency.

Some of the common side effects of this medicine include blurred or double vision, headache, nausea, vomiting, fatigue, rash, and diarrhea. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.  Please consult your doctor if these side effects bother you or do not go away.

Your doctor may advice for regular monitoring of sodium levels, as it may reduce the sodium levels in your blood (hyponatremia). Inform your doctor if you are taking oral contraceptive pills as this medicine reduces their levels in the body.

Uses of Normictal Tablet

Benefits of Normictal Tablet

Epilepsy/Seizures
Normictal 400mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Normictal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Normictal
  • Sleepiness
  • Blurred vision
  • Nausea
  • Headache
  • Vomiting
  • Double vision
  • Fatigue
  • Balance disorder (loss of balance)
  • Diarrhea
  • Impaired coordination
  • Vertigo
  • Decreased appetite
  • Decreased sodium level in blood
  • Dizziness
  • Rash

How to use Normictal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Normictal 400mg Tablet may be taken with or without food.

How Normictal Tablet works

Normictal 400mg Tablet is an anti epileptic medication. It works by blocking the voltage gated sodium channels that stabilizes the hyperexcited nerve cells in the brain. In this way, it treats seizures or fits.

All substitutes for Normictal 400mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • It may cause a reduction in blood sodium level (hyponatremia). Your doctor may monitor your blood sodium level regularly.
  • Inform your doctor if you notice skin reaction such as rash, skin peeling, and itching while using this medicine.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Normictal 400mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Normictal 400mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Normictal 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Normictal 400mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Normictal 400mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Normictal 400mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Normictal 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Normictal 400mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Normictal with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Ulipristal acetate (Oral Route)

Do not consume Ulipristal acetate with Eslicarbazepine. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Eslicarbazepine. Please consult your doctor.
Severe

Pazopanib (Oral Route)

Do not consume Pazopanib with Eslicarbazepine. Eslicarbazepine may reduce blood levels of Pazopanib.
Moderate

Rosuvastatin (Oral Route)

If concurrent use is essential, your doctor may monitor your cholesterol levels along with your overall treatment and adjust the doses as per the observations. Eslicarbazepine may reduce blood levels of Rosuvastatin.
Moderate

Atorvastatin (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Eslicarbazepine may reduce blood levels of Atorvastatin.
Moderate

Imatinib mesylate (Oral Route)

Do not consume Imatinib mesylate with Eslicarbazepine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Eslicarbazepine may reduce blood levels of Imatinib mesylate.

Frequently asked questions

No, stopping Normictal 400mg Tablet suddenly can increase your risk of having more seizures. Your doctor will advise you on how long you should take this medicine. If your doctor decides to stop Normictal 400mg Tablet, your dose will usually be reduced gradually. It is important that you complete your treatment as advised by your doctor or your symptoms may get worse.
Like all other anti-epileptic medicines, Normictal 400mg Tablet may also cause suicidal thoughts. However, this occurs only in a small number of people.
Inform your doctor if you are suffering from liver disease as few people have shown a negative effect on the liver with the use of Normictal 400mg Tablet. Your doctor may monitor your liver functions regularly.
Pay attention to any changes, especially sudden changes in mood, behaviour, thoughts or feelings. Keep all follow-up visits with your doctor as scheduled. Call your doctor as needed, especially if you are worried about any symptoms.
Normictal 400mg Tablet may cause allergic reactions or serious problems that may impact organs and other parts of your body like the liver or blood cells. Consult your doctor straight away if you develop rashes, hives, itchiness, swelling, trouble swallowing or difficulty in breathing.
Your doctor will guide you about activities that are okay for you.
If your blood sodium levels become low during the course of Normictal 400mg Tablet, you may experience worsening of seizures, confusion and decreased consciousness. Immediately consult your doctor if you develop any of these symptoms.
The dose of Normictal 400mg Tablet may need to be adjusted if you take Carbamazepine with Normictal 400mg Tablet. The reason being, Carbamazepine interferes with its working.

Fact Box

Chemical Class

Dibenzazepines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
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