


Nobese 10mg Capsule
Sibutramine (10mg)
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Nobese 10mg Capsule is a centrally acting medicine that was previously used in the management of obesity. It acts on chemical messengers in the brain involved in appetite regulation and satiety, which can reduce feelings of hunger and increase a sense of fullness after meals.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Aug 2026 | 01:01 AM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Aug 2026 | 01:01 AM (IST)
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General Information
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Product introduction
Because of safety concerns identified with its use, Nobese 10mg Capsule is banned by CDSCO in India and no longer recommended as a routine option for weight management.
Uses of Nobese Capsule
Benefits of Nobese Capsule
Management of Obesity
Obesity is a condition where excess body weight increases the risk of health problems such as diabetes and heart disease. Nobese 10mg Capsule helps support weight management by reducing appetite and helping control food intake. This can assist in gradual weight reduction when combined with a calorie-controlled diet and lifestyle changes, supporting better overall health outcomes.
Obesity is a condition where excess body weight increases the risk of health problems such as diabetes and heart disease. Nobese 10mg Capsule helps support weight management by reducing appetite and helping control food intake. This can assist in gradual weight reduction when combined with a calorie-controlled diet and lifestyle changes, supporting better overall health outcomes.
Side effects of Nobese Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nobese
- Nausea
- Dryness in mouth
- Dizziness
- Constipation
- Increased heart rate
- Loss of appetite
- Insomnia (difficulty in sleeping)
- High blood pressure
How to use Nobese Capsule
Take this medicine in the dose and duration as advised by your doctor. Nobese 10mg Capsule may be taken with or without food.
How Nobese Capsule works
Nobese 10mg Capsule lowers the appetite, which in turn decreases the food intake.
Quick tips
- Nobese 10mg Capsule is banned in India by the CDSCO due to an increased risk of serious cardiovascular events, including heart attack and stroke.
- Use of Nobese 10mg Capsule without medical supervision can lead to serious and potentially life-threatening side effects.
- Nobese 10mg Capsule should be used only under close medical supervision and for a short, clearly defined duration, if prescribed at all.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Nobese 10mg Capsule

Pregnancy
CONSULT YOUR DOCTOR
The safety of Nobese 10mg Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Nobese 10mg Capsule during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Nobese 10mg Capsule may cause side effects that could affect your ability to drive.

Kidney
CAUTION
Nobese 10mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Nobese 10mg Capsule is not recommended in patients with severe kidney disease.
Use of Nobese 10mg Capsule is not recommended in patients with severe kidney disease.

Liver
CAUTION
Nobese 10mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Use of Nobese 10mg Capsule is not recommended in these patients as the information available is very limited. No dose adjustment is recommended in patients with mild to moderate liver disease.
Use of Nobese 10mg Capsule is not recommended in these patients as the information available is very limited. No dose adjustment is recommended in patients with mild to moderate liver disease.
Interaction with drugs
Taking Nobese with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Ketoconazole (Oral Route)
Talk to your doctor if you notice any unusual symptoms. Sibutramine may increase the rate of release of Ketoconazole in the blood.
Moderate
Itraconazole (Oral Route)
Talk to your doctor if you notice any unusual symptoms. Sibutramine may decrease the metabolism of Itraconazole.
Moderate
Voriconazole (Injection Route)
Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Sibutramine may fasten the elimination of Voriconazole leading to reduced efficacy.
Moderate
Clopidogrel (Oral Route)
Talk to your doctor if you notice any unusual symptoms. Clopidogrel may decrease the metabolism of Sibutramine.
Moderate
Posaconazole (Oral Route)
Talk to your doctor if you notice any unusual symptoms. Sibutramine may reduce blood levels of the active form of Posaconazole.
Frequently asked questions
Nobese 10mg Capsule has been withdrawn in India
Nobese 10mg Capsule. when taken beyond the prescription period or at high doses may cause addiction. Please follow your doctor's advice for the duration and dose of Nobese 10mg Capsule
Nobese 10mg Capsule is not known to cause hair loss. Pease consult your doctor if you experience any such effect.
Fact Box
Chemical Class
Phenethylamine Derivative
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Centrally Acting Anti-Obesity Agents
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Daniel Pasteur
Address: sam building, ratwara sahib gurudwara road, sector 25, mohali-140301, punjab, india
Address: sam building, ratwara sahib gurudwara road, sector 25, mohali-140301, punjab, india
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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