Nitrol 20mg Injection
Prescription Required
Product introduction
Nitrol 20mg Injection is used in the treatment of certain kinds of breast and blood cancers. It is usually given alone or in together with certain other medicines as part of combination chemotherapy. It prevents cancer cells from growing, as a result of which they eventually die.
Nitrol 20mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, infection, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Nitrol 20mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, infection, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Nitrol Injection
Benefits of Nitrol Injection
In Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Nitrol 20mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Nitrol 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Breast cancer
Nitrol 20mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Nitrol 20mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
Side effects of Nitrol Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrol
- Absence of menstrual periods
- Anemia (low number of red blood cells)
- Decreased white blood cell count
- Hair loss
- Nausea
- Vomiting
How to use Nitrol Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nitrol Injection works
Nitrol 20mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Nitrol 20mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nitrol 20mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Nitrol 20mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Nitrol 20mg Injection may cause side effects which could affect your ability to drive.
Nitrol 20mg Injection can have a minor effect on your ability to drive. This is caused by the possible side effects, such as confusion or feeling tired
Nitrol 20mg Injection can have a minor effect on your ability to drive. This is caused by the possible side effects, such as confusion or feeling tired
Kidney
SAFE IF PRESCRIBED
Nitrol 20mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrol 20mg Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Nitrol 20mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nitrol 20mg Injection may not be needed in these patients. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Nitrol 20mg Injection
₹386/Injection
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Quick tips
- Nitrol 20mg Injection is given as an injection into veins under the supervision of a doctor.
Fact Box
Chemical Class
Anthracenedione Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents
Interaction with drugs
Taking Nitrol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Mitoxantrone.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Mitoxantrone from 1 day before until 1 day after taking Sargramostim.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Mitoxantrone from 14 days before until 24 days after taking Pegfilgras
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Mitoxantrone from 1 day before until 1 day after taking Molgramostim.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1715.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 952.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 932-33.
- Mitoxantrone. Rockland, Massachusetts: EMD Serono; 2012. [Accessed 26 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mitoxantrone. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
- Medscape. Mixantrone. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Country of origin: India
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