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Netalem 2mg Injection

Mitoxantrone (2mg/ml)

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Netalem 2mg Injection is used in the treatment of certain kinds of breast and blood cancers. It is usually given alone or in together with certain other medicines as part of combination chemotherapy. It prevents cancer cells from growing, as a result of which they eventually die.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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10 ml Injection

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General Information

Contains

Mitoxantrone (2mg/ml)

Marketer

Lemery

Storage

Store below 30°C

The content is shown in English

Product introduction

Netalem 2mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, infection, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Netalem Injection

Benefits of Netalem Injection

Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Netalem 2mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Breast cancer
Netalem 2mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Netalem 2mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Netalem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Netalem

Absence of menstrual periods
Anemia (low number of red blood cells)
Decreased white blood cell count
Hair loss
Nausea
Vomiting

How to use Netalem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Netalem Injection works

Netalem 2mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Quick tips

Netalem 2mg Injection is given as an injection into veins under the supervision of a doctor.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Netalem 2mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

Netalem 2mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Netalem 2mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Netalem 2mg Injection may cause side effects that could affect your ability to drive.
Netalem 2mg Injection can have a minor effect on your ability to drive. This is caused by the possible side effects, such as confusion or feeling tired

Kidney

SAFE IF PRESCRIBED

Netalem 2mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

SAFE IF PRESCRIBED

Netalem 2mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Netalem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Mitoxantrone.

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Mitoxantrone.

Severe

Trastuzumab (Injection Route)

Ensure a gap of at least 28 weeks after discontinuing Trastuzumab. If concurrent use is essential, watch out for the symptoms of heart failure, such as swelling, chest pain, shortness of breath, or palpitations, and consult your doctor if you experience them.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Fact Box

Chemical Class

Anthraquinones

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Cytotoxic Alkaloids

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Complete Blood Count

Peripheral Smear Examination

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1715.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 952.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 932-33.
Mitoxantrone. Rockland, Massachusetts: EMD Serono; 2012. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mitoxantrone. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lemery
Address: 11, Mahavir Mansion, 70 Trinity Street, Mumbai-400002

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Netalem 2mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Netalem 2mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Netalem Injection

Benefits of Netalem Injection

Side effects of Netalem Injection

How to use Netalem Injection

How Netalem Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Natalizumab (Injection Route)

Filgrastim (Injection Route)

Trastuzumab (Injection Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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